Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms.

Cao, Min; Day, Alison M; Galler, Martin; Latimer, Heather R; Byrne, Dominic P; Foy, Thomas W; Dwyer, Emilia; Bennett, Elise; Palmer, Jeremy; Morgan, Brian A; Eyers, Patrick A; Veal, Elizabeth A.

Mol Cell ; 83(17): 3140-3154.e7, 2023 09 07.

Artigo em Inglês | MEDLINE | ID: mdl-37572670

2.

Inactivation of a peroxiredoxin by hydrogen peroxide is critical for thioredoxin-mediated repair of oxidized proteins and cell survival.

Day, Alison M; Brown, Jonathon D; Taylor, Sarah R; Rand, Jonathan D; Morgan, Brian A; Veal, Elizabeth A.

Mol Cell ; 45(3): 398-408, 2012 Feb 10.

Artigo em Inglês | MEDLINE | ID: mdl-22245228

3.

Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation.

Day, Alison M; Smith, Deborah A; Ikeh, Mélanie A C; Haider, Mohammed; Herrero-de-Dios, Carmen M; Brown, Alistair J P; Morgan, Brian A; Erwig, Lars P; MacCallum, Donna M; Quinn, Janet.

PLoS Pathog ; 13(1): e1006131, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-28135328

4.

The GH130 Family of Mannoside Phosphorylases Contains Glycoside Hydrolases That Target ß-1,2-Mannosidic Linkages in Candida Mannan.

Cuskin, Fiona; Baslé, Arnaud; Ladevèze, Simon; Day, Alison M; Gilbert, Harry J; Davies, Gideon J; Potocki-Véronèse, Gabrielle; Lowe, Elisabeth C.

J Biol Chem ; 290(41): 25023-33, 2015 Oct 09.

Artigo em Inglês | MEDLINE | ID: mdl-26286752

5.

The fission yeast Schizosaccharomyces pombe as a model to understand how peroxiredoxins influence cell responses to hydrogen peroxide.

Veal, Elizabeth A; Tomalin, Lewis E; Morgan, Brian A; Day, Alison M.

Biochem Soc Trans ; 42(4): 909-16, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25109978

6.

Blocking Polyphosphate Mobilization Inhibits Pho4 Activation and Virulence in the Pathogen Candida albicans.

Ahmed, Yasmin; Ikeh, Mélanie A C; MacCallum, Donna M; Day, Alison M; Waldron, Kevin; Quinn, Janet.

mBio ; 13(3): e0034222, 2022 06 28.

Artigo em Inglês | MEDLINE | ID: mdl-35575514

7.

Hydrogen peroxide-sensitive cysteines in the Sty1 MAPK regulate the transcriptional response to oxidative stress.

Day, Alison M; Veal, Elizabeth A.

J Biol Chem ; 285(10): 7505-16, 2010 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-20061379

8.

Stress-Activated Protein Kinases in Human Fungal Pathogens.

Day, Alison M; Quinn, Janet.

Front Cell Infect Microbiol ; 9: 261, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31380304

9.

Influence of ylHog1 MAPK kinase on Yarrowia lipolytica stress response and erythritol production.

Rzechonek, Dorota A; Day, Alison M; Quinn, Janet; Mironczuk, Aleksandra M.

Sci Rep ; 8(1): 14735, 2018 10 03.

Artigo em Inglês | MEDLINE | ID: mdl-30283045

10.

Hog1 Regulates Stress Tolerance and Virulence in the Emerging Fungal Pathogen Candida auris.

Day, Alison M; McNiff, Megan M; da Silva Dantas, Alessandra; Gow, Neil A R; Quinn, Janet.

mSphere ; 3(5)2018 10 24.

Artigo em Inglês | MEDLINE | ID: mdl-30355673

11.

Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs.

Herrero-de-Dios, Carmen; Day, Alison M; Tillmann, Anna T; Kastora, Stavroula L; Stead, David; Salgado, Paula S; Quinn, Janet; Brown, Alistair J P.

mBio ; 9(2)2018 03 27.

Artigo em Inglês | MEDLINE | ID: mdl-29588408

12.

Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen.

Day, Alison M; Herrero-de-Dios, Carmen M; MacCallum, Donna M; Brown, Alistair J P; Quinn, Janet.

Sci Rep ; 7(1): 14340, 2017 10 30.

Artigo em Inglês | MEDLINE | ID: mdl-29085028

13.

Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis.

Ikeh, Mélanie A C; Kastora, Stavroula L; Day, Alison M; Herrero-de-Dios, Carmen M; Tarrant, Emma; Waldron, Kevin J; Banks, A Peter; Bain, Judith M; Lydall, David; Veal, Elizabeth A; MacCallum, Donna M; Erwig, Lars P; Brown, Alistair J P; Quinn, Janet.

Mol Biol Cell ; 27(17): 2784-801, 2016 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-27385340

14.

Glycan complexity dictates microbial resource allocation in the large intestine.

Rogowski, Artur; Briggs, Jonathon A; Mortimer, Jennifer C; Tryfona, Theodora; Terrapon, Nicolas; Lowe, Elisabeth C; Baslé, Arnaud; Morland, Carl; Day, Alison M; Zheng, Hongjun; Rogers, Theresa E; Thompson, Paul; Hawkins, Alastair R; Yadav, Madhav P; Henrissat, Bernard; Martens, Eric C; Dupree, Paul; Gilbert, Harry J; Bolam, David N.

Nat Commun ; 6: 7481, 2015 Jun 26.

Artigo em Inglês | MEDLINE | ID: mdl-26112186

15.

A peroxiredoxin promotes H2O2 signaling and oxidative stress resistance by oxidizing a thioredoxin family protein.

Brown, Jonathon D; Day, Alison M; Taylor, Sarah R; Tomalin, Lewis E; Morgan, Brian A; Veal, Elizabeth A.

Cell Rep ; 5(5): 1425-35, 2013 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-24268782

16.

Corrigendum: Glycan complexity dictates microbial resource allocation in the large intestine.

Rogowski, Artur; Briggs, Jonathon A; Mortimer, Jennifer C; Tryfona, Theodora; Terrapon, Nicolas; Lowe, Elisabeth C; Baslé, Arnaud; Morland, Carl; Day, Alison M; Zheng, Hongjun; Rogers, Theresa E; Thompson, Paul; Hawkins, Alastair R; Yadav, Madhav P; Henrissat, Bernard; Martens, Eric C; Dupree, Paul; Gilbert, Harry J; Bolam, David N.

Nat Commun ; 7: 10705, 2016 Feb 05.

Artigo em Inglês | MEDLINE | ID: mdl-26848059

17.

Hydrogen peroxide sensing and signaling.

Veal, Elizabeth A; Day, Alison M; Morgan, Brian A.

Mol Cell ; 26(1): 1-14, 2007 Apr 13.

Artigo em Inglês | MEDLINE | ID: mdl-17434122

18.

Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide.

Bozonet, Stephanie M; Findlay, Victoria J; Day, Alison M; Cameron, Jannine; Veal, Elizabeth A; Morgan, Brian A.

J Biol Chem ; 280(24): 23319-27, 2005 Jun 17.

Artigo em Inglês | MEDLINE | ID: mdl-15824112

19.

A 2-Cys peroxiredoxin regulates peroxide-induced oxidation and activation of a stress-activated MAP kinase.

Veal, Elizabeth A; Findlay, Victoria J; Day, Alison M; Bozonet, Stephanie M; Evans, Jennifer M; Quinn, Janet; Morgan, Brian A.

Mol Cell ; 15(1): 129-39, 2004 Jul 02.

Artigo em Inglês | MEDLINE | ID: mdl-15225554

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