Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

R-tPA Resistance Is Specific for Platelet-Rich Stroke Thrombi and Can Be Overcome by Targeting Nonfibrin Components.

Vandelanotte, Sarah; François, Olivier; Desender, Linda; Staessens, Senna; Vanhoorne, Alexander; Van Gool, Fréderick; Tersteeg, Claudia; Vanhoorelbeke, Karen; Vanacker, Peter; Andersson, Tommy; De Meyer, Simon F.

Stroke ; 55(5): 1181-1190, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38525646

2.

Pretreatment with a dual antiplatelet and anticoagulant (APAC) reduces ischemia-reperfusion injury in a mouse model of temporary middle cerebral artery occlusion-implications for neurovascular procedures.

Denorme, Frederik; Frösen, Juhana; Jouppila, Annukka; Lindgren, Antti; Resendiz-Nieves, Julio C; Manninen, Hannu; De Meyer, Simon F; Lassila, Riitta.

Acta Neurochir (Wien) ; 166(1): 137, 2024 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-38485848

3.

Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity.

Van Bael, Jens; Vandenbulcke, Aline; Ahmed-Belkacem, Abdelhakim; Guichou, Jean-François; Pawlotsky, Jean-Michel; Samyn, Jelle; Barendrecht, Arjan D; Maas, Coen; De Meyer, Simon F; Vanhoorelbeke, Karen; Tersteeg, Claudia.

Int J Mol Sci ; 24(8)2023 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-37108326

4.

Thromboinflammation in Brain Ischemia: Recent Updates and Future Perspectives.

De Meyer, Simon F; Langhauser, Friederike; Haupeltshofer, Steffen; Kleinschnitz, Christoph; Casas, Ana I.

Stroke ; 53(5): 1487-1499, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35360931

5.

Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura.

Roose, Elien; Schelpe, An-Sofie; Tellier, Edwige; Sinkovits, György; Joly, Bérangère S; Dekimpe, Charlotte; Kaplanski, Gilles; Le Besnerais, Maelle; Mancini, Ilaria; Falter, Tanja; Von Auer, Charis; Feys, Hendrik B; Reti, Marienn; Rossmann, Heidi; Vandenbulcke, Aline; Pareyn, Inge; Voorberg, Jan; Greinacher, Andreas; Benhamou, Ygal; Deckmyn, Hans; Fijnheer, Rob; Prohászka, Zoltan; Peyvandi, Flora; Lämmle, Bernhard; Coppo, Paul; De Meyer, Simon F; Veyradier, Agnès; Vanhoorelbeke, Karen.

Blood ; 136(3): 353-361, 2020 07 16.

Artigo em Inglês | MEDLINE | ID: mdl-32356859

6.

Vascular Endothelial Damage in the Pathogenesis of Organ Injury in Severe COVID-19.

Dupont, Annabelle; Rauch, Antoine; Staessens, Senna; Moussa, Mouhamed; Rosa, Mickael; Corseaux, Delphine; Jeanpierre, Emmanuelle; Goutay, Julien; Caplan, Morgan; Varlet, Pauline; Lefevre, Guillaume; Lassalle, Fanny; Bauters, Anne; Faure, Karine; Lambert, Marc; Duhamel, Alain; Labreuche, Julien; Garrigue, Delphine; De Meyer, Simon F; Staels, Bart; Vincent, Flavien; Rousse, Natacha; Kipnis, Eric; Lenting, Peter; Poissy, Julien; Susen, Sophie.

Arterioscler Thromb Vasc Biol ; 41(5): 1760-1773, 2021 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-33626910

7.

Studying Stroke Thrombus Composition After Thrombectomy: What Can We Learn?

Staessens, Senna; François, Olivier; Brinjikji, Waleed; Doyle, Karen M; Vanacker, Peter; Andersson, Tommy; De Meyer, Simon F.

Stroke ; 52(11): 3718-3727, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34517770

8.

Mechanical Characterization of Thrombi Retrieved With Endovascular Thrombectomy in Patients With Acute Ischemic Stroke.

Boodt, Nikki; Snouckaert van Schauburg, Philip R W; Hund, Hajo M; Fereidoonnezhad, Behrooz; McGarry, J Patrick; Akyildiz, Ali C; van Es, Adriaan C G M; De Meyer, Simon F; Dippel, Diederik W J; Lingsma, Hester F; van Beusekom, Heleen M M; van der Lugt, Aad; Gijsen, Frank J H.

Stroke ; 52(8): 2510-2517, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34078112

9.

The von Willebrand Factor A1 domain mediates thromboinflammation, aggravating ischemic stroke outcome in mice.

Denorme, Frederik; Martinod, Kimberly; Vandenbulcke, Aline; Denis, Cécile V; Lenting, Peter J; Deckmyn, Hans; Vanhoorelbeke, Karen; De Meyer, Simon F.

Haematologica ; 106(3): 819-828, 2021 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-32107335

10.

Detailed histological analysis of a thrombectomy-resistant ischemic stroke thrombus: a case report.

Staessens, Senna; François, Olivier; Desender, Linda; Vanacker, Peter; Dewaele, Tom; Sciot, Raf; Vanhoorelbeke, Karen; Andersson, Tommy; De Meyer, Simon F.

Thromb J ; 19(1): 11, 2021 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-33618719

11.

Thrombus heterogeneity in ischemic stroke.

Staessens, Senna; De Meyer, Simon F.

Platelets ; 32(3): 331-339, 2021 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-32310709

12.

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets.

Quach, M Edward; Dragovich, Matthew A; Chen, Wenchun; Syed, Anum K; Cao, Wenpeng; Liang, Xin; Deng, Wei; De Meyer, Simon F; Zhu, Guangheng; Peng, Jun; Ni, Heyu; Bennett, Carolyn M; Hou, Ming; Ware, Jerry; Deckmyn, Hans; Zhang, X Frank; Li, Renhao.

Blood ; 131(7): 787-796, 2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-29203584

13.

Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance.

Staessens, Senna; Denorme, Frederik; Francois, Olivier; Desender, Linda; Dewaele, Tom; Vanacker, Peter; Deckmyn, Hans; Vanhoorelbeke, Karen; Andersson, Tommy; De Meyer, Simon F.

Haematologica ; 105(2): 498-507, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-31048352

14.

Neutrophil Extracellular Traps in Arterial and Venous Thrombosis.

Laridan, Elodie; Martinod, Kimberly; De Meyer, Simon F.

Semin Thromb Hemost ; 45(1): 86-93, 2019 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-30634198

15.

N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura.

Tersteeg, Claudia; Roodt, Jan; Van Rensburg, Walter J; Dekimpe, Charlotte; Vandeputte, Nele; Pareyn, Inge; Vandenbulcke, Aline; Plaimauer, Barbara; Lamprecht, Seb; Deckmyn, Hans; Lopez, José A; De Meyer, Simon F; Vanhoorelbeke, Karen.

Blood ; 129(8): 1030-1038, 2017 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-28011677

16.

Generation of anti-idiotypic antibodies to detect anti-spacer antibody idiotopes in acute thrombotic thrombocytopenic purpura patients.

Schelpe, An-Sofie; Roose, Elien; Joly, Bérangère S; Pareyn, Inge; Mancini, Ilaria; Biganzoli, Marina; Deckmyn, Hans; Voorberg, Jan; Fijnheer, Rob; Peyvandi, Flora; De Meyer, Simon F; Coppo, Paul; Veyradier, Agnès; Vanhoorelbeke, Karen.

Haematologica ; 104(6): 1268-1276, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30523052

17.

Release of endothelial activation markers in lungs of patients with malaria-associated acute respiratory distress syndrome.

Pham, Thao-Thy; Punsawad, Chuchard; Glaharn, Supattra; De Meyer, Simon F; Viriyavejakul, Parnpen; Van den Steen, Philippe E.

Malar J ; 18(1): 395, 2019 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-31796023

18.

Neutrophil extracellular traps in ischemic stroke thrombi.

Laridan, Elodie; Denorme, Frederik; Desender, Linda; François, Olivier; Andersson, Tommy; Deckmyn, Hans; Vanhoorelbeke, Karen; De Meyer, Simon F.

Ann Neurol ; 82(2): 223-232, 2017 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-28696508

19.

ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice.

Denorme, Frederik; Langhauser, Friederike; Desender, Linda; Vandenbulcke, Aline; Rottensteiner, Hanspeter; Plaimauer, Barbara; François, Olivier; Andersson, Tommy; Deckmyn, Hans; Scheiflinger, Friedrich; Kleinschnitz, Christoph; Vanhoorelbeke, Karen; De Meyer, Simon F.

Blood ; 127(19): 2337-45, 2016 05 12.

Artigo em Inglês | MEDLINE | ID: mdl-26929275

20.

Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13.

Schelpe, An-Sofie; Orlando, Christelle; Ercig, Bogac; Geeroms, Chloë; Pareyn, Inge; Vandeputte, Nele; Velásquez Pereira, Leydi Carolina; Roose, Elien; Fostier, Karel; Nicolaes, Gerry A F; Deckmyn, Hans; De Meyer, Simon F; Vanhoorelbeke, Karen; Jochmans, Kristin.

Eur J Haematol ; 2018 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-29763513

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