Detalhe da pesquisa
1.
Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair.
Stem Cells
; 37(2): 284-294, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30372555
2.
Genome editing via delivery of Cas9 ribonucleoprotein.
Methods
; 121-122: 9-15, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28410976
3.
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Elife
; 112022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35147495
4.
High-level correction of the sickle mutation is amplified in vivo during erythroid differentiation.
iScience
; 25(6): 104374, 2022 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35633935
5.
Distance mapping in proteins using fluorescence spectroscopy: the tryptophan-induced quenching (TrIQ) method.
Biochemistry
; 49(45): 9722-31, 2010 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20886836
6.
Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells.
Cell Rep
; 32(9): 108093, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877675
7.
ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of ß-Globin.
Cell Rep
; 32(5): 107993, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32755585
8.
CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells.
PLoS One
; 14(1): e0208237, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30645582
9.
The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state.
J Mol Biol
; 365(5): 1257-65, 2007 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17118401
10.
Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering.
Elife
; 62017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28462777
11.
Covalent Protein Labeling and Improved Single-Molecule Optical Properties of Aqueous CdSe/CdS Quantum Dots.
ACS Nano
; 11(7): 6773-6781, 2017 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28618223
12.
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair.
Nat Biomed Eng
; 1: 889-901, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29805845
13.
Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.
Nat Biotechnol
; 34(3): 339-44, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26789497
14.
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells.
Sci Transl Med
; 8(360): 360ra134, 2016 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27733558
15.
The AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release.
Nat Struct Mol Biol
; 22(1): 73-80, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25486306
16.
Bidirectional helical motility of cytoplasmic dynein around microtubules.
Elife
; 3: e03205, 2014 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25069614
17.
Tension on the linker gates the ATP-dependent release of dynein from microtubules.
Nat Commun
; 5: 4587, 2014 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25109325
18.
Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domains.
Science
; 335(6065): 221-5, 2012 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22157083