Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Follicular regulatory T cells produce neuritin to regulate B cells.

Gonzalez-Figueroa, Paula; Roco, Jonathan A; Papa, Ilenia; Núñez Villacís, Lorena; Stanley, Maurice; Linterman, Michelle A; Dent, Alexander; Canete, Pablo F; Vinuesa, Carola G.

Cell ; 184(7): 1775-1789.e19, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-33711260

2.

The transcription factor BCL-6 controls early development of innate-like T cells.

Gioulbasani, Marianthi; Galaras, Alexandros; Grammenoudi, Sofia; Moulos, Panagiotis; Dent, Alexander L; Sigvardsson, Mikael; Hatzis, Pantelis; Kee, Barbara L; Verykokakis, Mihalis.

Nat Immunol ; 21(9): 1058-1069, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32719520

3.

CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.

Leong, Yew Ann; Chen, Yaping; Ong, Hong Sheng; Wu, Di; Man, Kevin; Deleage, Claire; Minnich, Martina; Meckiff, Benjamin J; Wei, Yunbo; Hou, Zhaohua; Zotos, Dimitra; Fenix, Kevin A; Atnerkar, Anurag; Preston, Simon; Chipman, Jeffrey G; Beilman, Greg J; Allison, Cody C; Sun, Lei; Wang, Peng; Xu, Jiawei; Toe, Jesse G; Lu, Hao K; Tao, Yong; Palendira, Umaimainthan; Dent, Alexander L; Landay, Alan L; Pellegrini, Marc; Comerford, Iain; McColl, Shaun R; Schacker, Timothy W; Long, Heather M; Estes, Jacob D; Busslinger, Meinrad; Belz, Gabrielle T; Lewin, Sharon R; Kallies, Axel; Yu, Di.

Nat Immunol ; 17(10): 1187-96, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27487330

4.

Targeted checkpoint control of B cells undergoing positive selection in germinal centers by follicular regulatory T cells.

Ke, Fang; Benet, Zachary L; Shelyakin, Pavel; Britanova, Olga V; Gupta, Neetu; Dent, Alexander L; Moore, Bethany B; Grigorova, Irina L.

Proc Natl Acad Sci U S A ; 121(5): e2304020121, 2024 Jan 30.

Artigo em Inglês | MEDLINE | ID: mdl-38261619

5.

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice.

Watchmaker, Payal B; Lahl, Katharina; Lee, Mike; Baumjohann, Dirk; Morton, John; Kim, Sun Jung; Zeng, Ruizhu; Dent, Alexander; Ansel, K Mark; Diamond, Betty; Hadeiba, Husein; Butcher, Eugene C.

Nat Immunol ; 15(1): 98-108, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24292363

6.

Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response.

Dadelahi, Alexis S; Abushahba, Mostafa F N; Ponzilacqua-Silva, Bárbara; Chambers, Catherine A; Moley, Charles R; Lacey, Carolyn A; Dent, Alexander L; Skyberg, Jerod A.

PLoS Pathog ; 19(9): e1011672, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37721965

7.

Nonbinary Roles for T Follicular Helper Cells and T Follicular Regulatory Cells in the Germinal Center Response.

Chen, Qiang; Dent, Alexander L.

J Immunol ; 211(1): 15-22, 2023 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-37339403

8.

Evidence that High-Affinity IgE Can Develop in the Germinal Center in the Absence of an IgG1-Switched Intermediate.

Chen, Qiang; Liu, Hong; Luling, Noelle; Reinke, Julia; Dent, Alexander L.

J Immunol ; 210(7): 905-915, 2023 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-36779803

9.

Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A.

Bunker, Jeffrey J; Flynn, Theodore M; Koval, Jason C; Shaw, Dustin G; Meisel, Marlies; McDonald, Benjamin D; Ishizuka, Isabel E; Dent, Alexander L; Wilson, Patrick C; Jabri, Bana; Antonopoulos, Dionysios A; Bendelac, Albert.

Immunity ; 43(3): 541-53, 2015 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-26320660

10.

Dichotomous effects of cellular expression of STAT3 on tumor growth of HNSCC.

Bickett, Thomas E; Knitz, Michael W; Piper, Miles; Oweida, Ayman J; Gadwa, Jacob; Darragh, Laurel B; Nguyen, Diemmy; Bhatia, Shilpa; Bhuvane, Shiv; Phan, Andy V; Van Court, Benjamin; Corbo, Sophia; Pham, Tiffany; Dent, Alexander L; Lenz, Laurel; Karam, Sana D.

Mol Ther ; 30(3): 1149-1162, 2022 03 02.

Artigo em Inglês | MEDLINE | ID: mdl-34793974

11.

It takes CK2 to suppress TH2.

Sawant, Deepali V; Dent, Alexander L.

Nat Immunol ; 16(3): 224-5, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25689435

12.

Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling.

Kusumanchi, Praveen; Liang, Tiebing; Zhang, Ting; Ross, Ruth Ann; Han, Sen; Chandler, Kristina; Oshodi, Adepeju; Jiang, Yanchao; Dent, Alexander L; Skill, Nicholas J; Huda, Nazmul; Ma, Jing; Yang, Zhihong; Liangpunsakul, Suthat.

Hepatology ; 74(3): 1234-1250, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-33710653

13.

BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection.

Zhu, Bibo; Zhang, Ruixuan; Li, Chaofan; Jiang, Li; Xiang, Min; Ye, Zhenqing; Kita, Hirohito; Melnick, Ari M; Dent, Alexander L; Sun, Jie.

Proc Natl Acad Sci U S A ; 116(24): 11888-11893, 2019 06 11.

Artigo em Inglês | MEDLINE | ID: mdl-31138703

14.

Inhibition of stearoyl-CoA desaturases suppresses follicular help T- and germinal center B- cell responses.

Son, Young Min; Cheon, In Su; Goplen, Nick P; Dent, Alexander L; Sun, Jie.

Eur J Immunol ; 50(7): 1067-1077, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32133634

15.

Bcl6 and Blimp1 reciprocally regulate ST2⁺ Treg-cell development in the context of allergic airway inflammation.

Koh, Byunghee; Ulrich, Benjamin J; Nelson, Andrew S; Panangipalli, Gayathri; Kharwadkar, Rakshin; Wu, Wenting; Xie, Markus M; Fu, Yongyao; Turner, Matthew J; Paczesny, Sophie; Janga, Sarath Chandra; Dent, Alexander L; Kaplan, Mark H.

J Allergy Clin Immunol ; 146(5): 1121-1136.e9, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32179158

16.

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-ß1 secretion and hematopoiesis in mice.

Capitano, Maegan; Zhao, Liang; Cooper, Scott; Thorsheim, Chelsea; Suzuki, Aae; Huang, Xinxin; Dent, Alexander L; Marks, Michael S; Abrams, Charles S; Broxmeyer, Hal E.

Blood ; 132(10): 1027-1038, 2018 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-30042096

17.

Lipids-Ð¯-Us: peroxisome generation of iNKT ligands.

Brutkiewicz, Randy R; Dent, Alexander L.

Nat Immunol ; 13(5): 435-6, 2012 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-22513327

18.

The Legend of Delta: Finding a New TCR Gene.

Dent, Alexander L.

J Immunol ; 208(9): 2081-2083, 2022 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-35470263

19.

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.

Olson, Matthew R; Ulrich, Benjamin J; Hummel, Sarah A; Khan, Ibrahim; Meuris, Brice; Cherukuri, Yesesri; Dent, Alexander L; Janga, Sarath Chandra; Kaplan, Mark H.

J Immunol ; 198(11): 4352-4359, 2017 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-28468971

20.

Airway exposure initiates peanut allergy by involving the IL-1 pathway and T follicular helper cells in mice.

Dolence, Joseph J; Kobayashi, Takao; Iijima, Koji; Krempski, James; Drake, Li Y; Dent, Alexander L; Kita, Hirohito.

J Allergy Clin Immunol ; 142(4): 1144-1158.e8, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29247716

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