1.
Clin Chim Acta
; 82(1-2): 55-9, 1978 Jan 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-412623
RESUMO
Tryptophan pyrrolase, a microsomal enzyme responsible for the break-down of tryptophan, has been detected in Bufo melanostictus. The enzyme has been found to be deactivated under influence of antivitiligo drug psoralene and activated by hydroquinone, an inhibitor of tyrosinase. Tryptophan pyrrolase has been found to have an antagonistic relationship with tyrosinase in Bufo melanostictus. The implication of the results has been discussed in relation to melanogenesis in vitiligo.
Assuntos
Catecol Oxidase/metabolismo , Melanócitos/fisiologia , Monofenol Mono-Oxigenase/metabolismo , Pele/enzimologia , Triptofano Oxigenase/metabolismo , Animais , Bufonidae , Ficusina/farmacologia , Hidroquinonas/farmacologia , Cinética , Fígado/efeitos dos fármacos , Fígado/enzimologia , Masculino , Pele/efeitos dos fármacos
2.
Clin Chim Acta
; 72(2): 219-22, 1976 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-824075