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1.
Ann Surg Oncol ; 30(12): 7036-7045, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37507555

RESUMO

BACKGROUND: We suspect that morbidity from both sentinel lymph node biopsy (SLNB) and axillary lymph node dissection (ALND) has been inadequately evaluated to date. Current methodologies are subjective and susceptible to bias. Objective assessment using wearable activity monitors (WAMs) would allow quantitative analysis of recovery by measuring physical activity (PA) and could provide evidence for axillary de-escalation. PATIENTS AND METHODS: A prospective, single center, observational study was conducted from February 2020 to May 2022. Consecutive patients undergoing breast and/or reconstructive surgery and axillary surgeries were identified from the operating schedules. Patients wore WAMs for an average of 3 days prior to surgery and up to 2 weeks following surgery. In total, 56 patients with breast cancer were recruited, of whom 35 underwent SLNB and 21 ALND. RESULTS: Patients who underwent ALND experienced significantly worse PA compared with those who underwent SLNB in week 2 (median 66.4% versus 72.7%, p = 0.015). Subgroup analysis revealed significantly lower PA in simple mastectomy (Mx)-ALND versus Mx-SLNB (median 90.3% versus 70.5%, p = 0.015) in week 2. The PA for SLNB did not return to baseline at 2 weeks after surgery. CONCLUSIONS: Compared with SLNB, ALND results in a lower PA level in week 2. The findings also indicate that SLNB has a protracted effect on PA levels, which extend to 2 weeks postoperatively. Monitoring recovery objectively following breast cancer surgery provides patients and surgeons with more information regarding the predicted outcomes of their surgery, which can drive the development of a personalized rehabilitation program.


Assuntos
Neoplasias da Mama , Linfonodo Sentinela , Dispositivos Eletrônicos Vestíveis , Humanos , Feminino , Biópsia de Linfonodo Sentinela/métodos , Neoplasias da Mama/cirurgia , Neoplasias da Mama/patologia , Estudos Prospectivos , Mastectomia , Metástase Linfática , Excisão de Linfonodo/métodos , Axila/patologia , Linfonodo Sentinela/patologia
2.
Ann Surg Oncol ; 28(10): 5597-5609, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34309777

RESUMO

BACKGROUND: Current validated tools to measure upper limb dysfunction after breast cancer treatment, such as questionnaires, are prone to recall bias and do not enable comparisons between patients. This study aimed to test the feasibility of wearable activity monitors (WAMs) for achieving a continuous, objective assessment of functional recovery by measuring peri-operative physical activity (PA). METHODS: A prospective, single-center, non-randomized, observational study was conducted. Patients undergoing breast and axillary surgery were invited to wear WAMs on both wrists in the peri-operative period and then complete upper limb function (DASH) and quality-of-life (EQ-5D-5L) questionnaires. Statistical analyses were performed to determine the construct validity and concurrent validity of WAMs. RESULTS: The analysis included 39 patients with a mean age of 55 ± 13.2 years. Regain of function on the surgically treated side was observed to be an increase of arm activity as a percentage of preoperative levels, with the greatest increase observed between the postoperative days 1 and 2. The PA was significantly greater on the side not treated by surgery than on the surgically treated side after week 1 (mean PA, 75.8% vs. 62.3%; p < 0.0005) and week 2 (mean PA, 91.6% vs. 77.4%; p < 0.005). Subgroup analyses showed differences in recovery trends between different surgical procedures. Concurrent validity was demonstrated by a significant negative moderate correlation between the PA and DASH questionnaires (R = -0.506; p < 0.05). CONCLUSION: This study demonstrated the feasibility and validity of WAMs to objectively measure postoperative recovery of upper limb function after breast surgery, providing a starting point for personalized rehabilitation through early detection of upper limb physical morbidity.


Assuntos
Neoplasias da Mama , Dispositivos Eletrônicos Vestíveis , Adulto , Idoso , Neoplasias da Mama/cirurgia , Feminino , Humanos , Mastectomia , Pessoa de Meia-Idade , Morbidade , Estudos Prospectivos , Qualidade de Vida , Inquéritos e Questionários
6.
PLoS One ; 16(9): e0257325, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34506586

RESUMO

BACKGROUND: Preservation of joint line height is an important factor in post-operative function after Total Knee Arthroplasty (TKA). This is the first study investigating the reliability of the novel Imperial Joint Line Congruency Measurement (IJLCM) technique for the assessment of joint line height using plain radiographs. METHODS: The reliability of two techniques used to measure joint line height on pre-operative and post-operative plain radiographs is presented. 120 patients that underwent TKA from 6 different international centres were included. Measurements were performed using each technique by two senior orthopaedic surgeons at two different timepoints (test-retest). Two undergraduate medical students performed joint line measurements using the most reproducible of the two techniques on 40 pre-operative and post-operative images to establish the reliability of the measurement technique. RESULTS: The IJLCM demonstrated an average absolute difference of 1.83mm (CI 1.56-2.10mm) and excellent inter and intra-rater reliability between senior orthopaedic surgeons (>0.92 (CI 0.88-0.94) when measuring joint line height on plain radiographs. Overall Crohnbach's alpha over 0.92 confirmed internal consistency. Measurements performed using the control technique as previously described by Figgie et al. had an average absolute difference of 5.75mm (5.17-6.32mm). Comparison of measurements by senior orthopaedic surgeons and medical students using the IJLCM technique with ANOVA and student's t-test demonstrated acceptable agreement and inter-rater reliability of >0.92 (0.87-0.95). CONCLUSION: This study shows excellent accuracy, precision, and reliability of the novel IJLCM technique. Furthermore, excellent agreement between senior orthopaedic surgeons and medical students when using the IJLCM could be shown. The IJLCM technique is reliable for joint line assessment.


Assuntos
Artroplastia do Joelho/métodos , Articulação do Joelho/diagnóstico por imagem , Cirurgiões Ortopédicos , Ortopedia/normas , Radiografia/métodos , Humanos , Articulação do Joelho/cirurgia , Prótese do Joelho , Modelos Estatísticos , Variações Dependentes do Observador , Reprodutibilidade dos Testes
7.
Int J Med Robot ; 17(6): e2308, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34288356

RESUMO

BACKGROUND: The purpose of this study was to compare total blood loss and the risk of receiving a blood transfusion in robotic-assisted total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) against conventional jig-based techniques. METHODS: Robotic TKA (n = 50) and UKA (n = 50) patients were matched to contemporary controls for TKA (n = 50) and UKA (n = 50) and retrospectively analysed. RESULTS: Robotic TKA patients experienced 23.7% less blood loss compared to conventional TKA patients (911.0 ml vs 1193.7 ml, p < 0.01), and were associated with an 83% relative risk reduction of receiving a transfusion (2% of patients vs 12%, p = 0.02). Robotic UKA patients did not demonstrate less blood loss compared to corresponding controls (821.7 ml vs 854.7 ml, p = 0.69). Both UKA groups received no transfusions. CONCLUSIONS: Robotic surgical systems in TKA reduces blood loss and lowers the risk of requiring a blood transfusion. In UKA, robotic-assisted arthroplasty did not reduce blood loss compared to conventional arthroplasty.


Assuntos
Artroplastia do Joelho , Osteoartrite do Joelho , Procedimentos Cirúrgicos Robóticos , Artroplastia do Joelho/efeitos adversos , Transfusão de Sangue , Humanos , Articulação do Joelho/cirurgia , Osteoartrite do Joelho/cirurgia , Estudos Retrospectivos , Procedimentos Cirúrgicos Robóticos/efeitos adversos , Resultado do Tratamento
8.
Mil Med ; 181(8): 887-94, 2016 08.
Artigo em Inglês | MEDLINE | ID: mdl-27483529

RESUMO

OBJECTIVE: Identifying Department of Defense (DoD) occupations affected by injuries to the head and sensory systems. METHODS: We explored the Defense Medical Epidemiology Database to identify occupations with the highest incidence of injured personnel, then ranked how frequently they occurred in a top 10 list for each of four injury categories (head/brain, visual, auditory, vestibular) encompassing 25 injury codes. Across all four categories, the most affected occupations were identified, among which we chose three Army combat-related military occupational specialties (MOSs) for detailed study. We identified skills needed to perform these MOSs and explored whether MOS-critical deficits could be expected following the injuries. RESULTS: Some DoD occupations are more likely to suffer from these injuries, including Infantry, Combat Operations Control, Artillery/Gunnery, Motor Vehicle Operator, Combat Engineering, and Armor/Amphibious. Within these DoD occupations, we explored three Army combatant MOSs: Infantry (11B), Cavalry Scout (19D), and Artillery (13B), confirming that these jobs are likely to be disrupted by injuries within the four categories. CONCLUSIONS: Head and sensory injuries disproportionately affect certain military occupations. Relatively few injuries disrupt combat-related abilities that are job critical (e.g., firearms operation) and job specific (e.g., Artillery gunnery problems); these should be the focus of efforts to improve rehabilitation and RTD outcomes.


Assuntos
Traumatismos Craniocerebrais/complicações , Classificação Internacional de Doenças/classificação , Militares , Ocupações , Transtornos de Sensação/complicações , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Retorno ao Trabalho , Recursos Humanos
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