Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.

Zhao, Yongxu; Li, Shuang; Chen, Yanhao; Wang, Yuchen; Wei, Yuda; Zhou, Tingting; Zhang, Yuwei; Yang, Yuanyuan; Chen, Lanlan; Liu, Yan; Hu, Cheng; Zhou, Ben; Ding, Qiurong.

Mol Cell ; 83(7): 1093-1108.e8, 2023 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-36863348

2.

Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase.

Yuan, Juanjuan; Ma, Yunqing; Huang, Tao; Chen, Yanhao; Peng, Yuanzheng; Li, Bing; Li, Jia; Zhang, Yuchen; Song, Bing; Sun, Xiaofang; Ding, Qiurong; Song, Yan; Chang, Xing.

Mol Cell ; 72(2): 380-394.e7, 2018 10 18.

Artigo em Inglês | MEDLINE | ID: mdl-30293782

3.

Excessive apoptosis of Rip1-deficient T cells leads to premature aging.

Wang, Lingxia; Zhang, Xixi; Zhang, Haiwei; Lu, Kaili; Li, Ming; Li, Xiaoming; Ou, Yangjing; Zhao, Xiaoming; Wu, Xiaoxia; Wu, Xuanhui; Liu, Jianling; Xing, Mingyan; Liu, Han; Zhang, Yue; Tan, Yongchang; Li, Fang; Deng, Xiaoxue; Deng, Jiangshan; Zhang, Xiaojie; Li, Jinbao; Zhao, Yuwu; Ding, Qiurong; Wang, Haikun; Wang, Xiuzhe; Luo, Yan; Zhou, Ben; Zhang, Haibing.

EMBO Rep ; 24(12): e57925, 2023 Dec 06.

Artigo em Inglês | MEDLINE | ID: mdl-37965894

4.

Structural and functional insights into the epigenetic regulator MRG15.

Jiang, Nan; Li, Yong-Bo; Jin, Jia-Yu; Guo, Jie-Yu; Ding, Qiu-Rong; Meng, Dan; Zhi, Xiu-Ling.

Acta Pharmacol Sin ; 45(5): 879-889, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38191914

5.

MRG15 aggravates non-alcoholic steatohepatitis progression by regulating the mitochondrial proteolytic degradation of TUFM.

Tian, Cheng; Min, Xuewen; Zhao, Yongxu; Wang, Yuchen; Wu, Xiaoshan; Liu, Situn; Dou, Wei; Zhou, Tingting; Liu, Yan; Luo, Rongkui; Li, Zhigang; Lui, Kathy O; Li, Yu; Zhou, Ben; Ding, Qiurong.

J Hepatol ; 77(6): 1491-1503, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-35985547

6.

NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr-143.

Su, Wei; Hu, Hao; Ding, Qiurong; Wang, Min; Zhu, Yan; Zhang, Zhaochao; Geng, Zihan; Lin, Shengli; Zhou, Pinghong.

Cell Commun Signal ; 20(1): 87, 2022 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-35705994

7.

In Vivo AAV-CRISPR/Cas9-Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia.

Zhao, Huan; Li, Yan; He, Lingjuan; Pu, Wenjuan; Yu, Wei; Li, Yi; Wu, Yan-Ting; Xu, Chenming; Wei, Yuda; Ding, Qiurong; Song, Bao-Liang; Huang, Hefeng; Zhou, Bin.

Circulation ; 141(1): 67-79, 2020 01 07.

Artigo em Inglês | MEDLINE | ID: mdl-31779484

8.

Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells.

Luo, Xiao-Ling; Zhang, Peng; Liu, Xiangyuan; Huang, Shiqian; Rao, Sen-Le; Ding, Qiurong; Yang, Huang-Tian.

Pflugers Arch ; 473(7): 991-1007, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34031754

9.

microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle.

Li, Yan; Jiang, Jingjing; Liu, Wei; Wang, Hui; Zhao, Lei; Liu, Shengnan; Li, Peng; Zhang, Shengjie; Sun, Chao; Wu, Yuting; Yu, Shuxian; Li, Xihua; Zhang, Hui; Qian, Haifeng; Zhang, Duo; Guo, Feifan; Zhai, Qiwei; Ding, Qiurong; Wang, Li; Ying, Hao.

Proc Natl Acad Sci U S A ; 115(46): E10849-E10858, 2018 11 13.

Artigo em Inglês | MEDLINE | ID: mdl-30373812

10.

[Applications of stem cell disease models in liver metabolic research and drug development].

Wu, Xiao-Shan; Li, Shuang; Ding, Qiu-Rong.

Sheng Li Xue Bao ; 73(5): 694-706, 2021 Oct 25.

Artigo em Zh | MEDLINE | ID: mdl-34708227

11.

Cas9-nickase-mediated genome editing corrects hereditary tyrosinemia in rats.

Shao, Yanjiao; Wang, Liren; Guo, Nana; Wang, Shengfei; Yang, Lei; Li, Yajing; Wang, Mingsong; Yin, Shuming; Han, Honghui; Zeng, Li; Zhang, Ludi; Hui, Lijian; Ding, Qiurong; Zhang, Jiqin; Geng, Hongquan; Liu, Mingyao; Li, Dali.

J Biol Chem ; 293(18): 6883-6892, 2018 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-29507093

12.

CRISPR/Cas9 with single guide RNA expression driven by small tRNA promoters showed reduced editing efficiency compared to a U6 promoter.

Wei, Yuda; Qiu, Yan; Chen, Yanhao; Liu, Gaigai; Zhang, Yongxian; Xu, Luwei; Ding, Qiurong.

RNA ; 23(1): 1-5, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27742910

13.

Porphyromonas gingivalis-derived lipopolysaccharide causes excessive hepatic lipid accumulation via activating NF-κB and JNK signaling pathways.

Ding, Lu-Yang; Liang, Li-Zong; Zhao, Yong-Xu; Yang, Ya-Nan; Liu, Feng; Ding, Qiu-Rong; Luo, Li-Jun.

Oral Dis ; 25(7): 1789-1797, 2019 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-31283861

14.

CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo-Brief Report.

Wang, Xiao; Raghavan, Avanthi; Chen, Tao; Qiao, Lyon; Zhang, Yongxian; Ding, Qiurong; Musunuru, Kiran.

Arterioscler Thromb Vasc Biol ; 36(5): 783-6, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-26941020

15.

Applications of genome editing tools in precision medicine research.

Li, Shuang; Yang, Yuan-yuan; Qiu, Yan; Chen, Yanhao; Xu, Lu-wei; Ding, Qiu-rong.

Yi Chuan ; 39(3): 177-188, 2017 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-28420614

16.

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing.

Ding, Qiurong; Strong, Alanna; Patel, Kevin M; Ng, Sze-Ling; Gosis, Bridget S; Regan, Stephanie N; Cowan, Chad A; Rader, Daniel J; Musunuru, Kiran.

Circ Res ; 115(5): 488-92, 2014 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-24916110

17.

Correction: Cas9-nickase-mediated genome editing corrects hereditary tyrosinemia in rats.

Shao, Yanjiao; Wang, Liren; Guo, Nana; Wang, Shengfei; Yang, Lei; Li, Yajing; Wang, Mingsong; Yin, Shuming; Han, Honghui; Zeng, Li; Zhang, Ludi; Hui, Lijian; Ding, Qiurong; Zhang, Jiqin; Geng, Hongquan; Liu, Mingyao; Li, Dali.

J Biol Chem ; 294(21): 8348, 2019 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-31127060

18.

Spotlight on gene therapy in China.

Ding, Qiurong.

Gene Ther ; 27(7-8): 307-308, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32728206

19.

[Efficient genome editing in human pluripotent stem cells through CRISPR/Cas9].

Liu, Gai-gai; Li, Shuang; Wei, Yu-da; Zhang, Yong-xian; Ding, Qiu-rong.

Yi Chuan ; 37(11): 1167-73, 2015 11.

Artigo em Zh | MEDLINE | ID: mdl-26582531

20.

Use of genome editing tools in human stem cell-based disease modeling and precision medicine.

Wei, Yu-da; Li, Shuang; Liu, Gai-gai; Zhang, Yong-xian; Ding, Qiu-rong.

Yi Chuan ; 37(10): 983-91, 2015 10.

Artigo em Inglês | MEDLINE | ID: mdl-26496750

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