Detalhe da pesquisa
1.
Phase I study, and dosing regimen selection for a pivotal COVID-19 trial of GST-HG171.
Antimicrob Agents Chemother
; 68(1): e0111523, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38099673
2.
Improvement of Pre-check and Triage Efficiency and Guarantee of Maternal and Infant Safety in Pandemic Situation.
Altern Ther Health Med
; 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38639611
3.
Safety, tolerability, pharmacokinetics, and antiviral activity of the novel core protein allosteric modulator ZM-H1505R (Canocapavir) in chronic hepatitis B patients: a randomized multiple-dose escalation trial.
BMC Med
; 21(1): 98, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927420
4.
Safety, pharmacokinetics and antiviral activity of ABI-H2158, a hepatitis B virus core inhibitor: A randomized, placebo-controlled phase 1 study.
J Viral Hepat
; 30(3): 209-222, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302125
5.
HLX22, an anti-HER-2 monoclonal antibody, in patients with advanced solid tumors overexpressing human epidermal growth factor receptor 2: an open-label, dose-escalation, phase 1 trial.
Invest New Drugs
; 41(3): 473-482, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37140695
6.
Pradefovir Treatment in Patients With Chronic Hepatitis B: Week 24 Results From a Multicenter, Double-Blind, Randomized, Noninferiority, Phase 2 Trial.
Clin Infect Dis
; 74(11): 1925-1932, 2022 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34487151
7.
Safety, Tolerability, and Pharmacokinetics of the Novel Hepatitis B Virus Expression Inhibitor GST-HG131 in Healthy Chinese Subjects: a First-in-Human Single- and Multiple-Dose Escalation Trial.
Antimicrob Agents Chemother
; 66(5): e0009422, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35404074
8.
PCSK9 inhibitor recaticimab for hypercholesterolemia on stable statin dose: a randomized, double-blind, placebo-controlled phase 1b/2 study.
BMC Med
; 20(1): 13, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35039035
9.
Cobalt(III)-Catalyzed and DMSO-Involved Allylation of 1,3-Dicarbonyl Compounds with Alkenes.
J Org Chem
; 87(21): 14352-14363, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36263891
10.
Antiviral Activity and Pharmacokinetics of the Hepatitis B Virus (HBV) Capsid Assembly Modulator GLS4 in Patients With Chronic HBV Infection.
Clin Infect Dis
; 73(2): 175-182, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32649736
11.
Safety, Tolerability, and Pharmacokinetics of the Novel Hepatitis B Virus Capsid Assembly Modulator GST-HG141 in Healthy Chinese Subjects: a First-in-Human Single- and Multiple-Dose Escalation Trial.
Antimicrob Agents Chemother
; 65(10): e0122021, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34280012
12.
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified.
Acta Pharmacol Sin
; 42(2): 311-322, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32860005
13.
Coblopasvir and sofosbuvir for treatment of chronic hepatitis C virus infection in China: A single-arm, open-label, phase 3 trial.
Liver Int
; 40(11): 2685-2693, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33047868
14.
Pharmacokinetics and pharmacodynamics of rongliflozin, a novel selective inhibitor of sodium-glucose co-transporter-2, in people with type 2 diabetes mellitus.
Diabetes Obes Metab
; 22(2): 191-202, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31588657
15.
Pharmacokinetics, pharmacodynamics and tolerability of single and multiple doses of janagliflozin, a sodium-glucose co-transporter-2 inhibitor, in Chinese people with type 2 diabetes mellitus.
Diabetes Obes Metab
; 22(12): 2316-2324, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32744380
16.
Impacts of CYP2C19 genetic polymorphisms on bioavailability and effect on platelet adhesion of vicagrel, a novel thienopyridine P2Y12 inhibitor.
Br J Clin Pharmacol
; 86(9): 1860-1874, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32267573
17.
IL-33 Inhibits Hepatitis B Virus through Its Receptor ST2 in Hydrodynamic HBV Mouse Model.
Mediators Inflamm
; 2020: 1403163, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32410845
18.
Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids.
Gut
; 68(7): 1311-1322, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30121625
19.
Parallel domestication with a broad mutational spectrum of determinate stem growth habit in leguminous crops.
Plant J
; 96(4): 761-771, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30112860
20.
Transitioning from NAFLD to MAFLD and MASLD: Consistent prevalence and risk factors in a Chinese cohort.
J Hepatol
; 80(4): e154-e155, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37827472