Detalhe da pesquisa
1.
ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis.
Hum Mol Genet
; 32(14): 2386-2398, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37220877
2.
Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research.
Cell Mol Life Sci
; 73(19): 3693-709, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27154043
3.
ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation.
Sci Rep
; 13(1): 20467, 2023 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993492
4.
The mRNA-based reprogramming of fibroblasts from a SOD1E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007.
Stem Cell Res
; 42: 101701, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32006803
5.
A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling.
Cells
; 9(9)2020 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32887382
6.
Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNFS621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming.
Stem Cell Res
; 40: 101530, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31445393
7.
The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.
Cells
; 8(6)2019 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31200561
8.
Impairments in Motor Neurons, Interneurons and Astrocytes Contribute to Hyperexcitability in ALS: Underlying Mechanisms and Paths to Therapy.
Mol Neurobiol
; 55(2): 1410-1418, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28160214
9.
Viral-free generation and characterization of a human induced pluripotent stem cell line from dermal fibroblasts.
Stem Cell Res
; 32: 135-138, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30278375
10.
Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1.
Stem Cell Res
; 31: 227-230, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30138848
11.
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.
Mol Neurodegener
; 10: 57, 2015 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26520394