Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference.

Bast, Robert C; Matulonis, Ursula A; Sood, Anil K; Ahmed, Ahmed A; Amobi, Adaobi E; Balkwill, Frances R; Wielgos-Bonvallet, Monicka; Bowtell, David D L; Brenton, James D; Brugge, Joan S; Coleman, Robert L; Draetta, Giulio F; Doberstein, Kai; Drapkin, Ronny I; Eckert, Mark A; Edwards, Robert P; Elias, Kevin M; Ennis, Darren; Futreal, Andrew; Gershenson, David M; Greenberg, Roger A; Huntsman, David G; Ji, Jennifer Xiao Ye; Kohn, Elise C; Iavarone, Claudia; Lengyel, Ernst R; Levine, Douglas A; Lord, Christopher J; Lu, Zhen; Mills, Gordon B; Modugno, Francesmary; Nelson, Brad H; Odunsi, Kunle; Pilsworth, Jessica A; Rottapel, Robert K; Powell, Daniel J; Shen, Li; Shih, Ie-Ming; Spriggs, David R; Walton, Josephine; Zhang, Kaiyang; Zhang, Rugang; Zou, Lee.

Cancer ; 125(12): 1963-1972, 2019 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-30835824

2.

L1CAM in human cancer.

Altevogt, Peter; Doberstein, Kai; Fogel, Mina.

Int J Cancer ; 138(7): 1565-76, 2016 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-26111503

3.

CCNE1 amplification and centrosome number abnormality in serous tubal intraepithelial carcinoma: further evidence supporting its role as a precursor of ovarian high-grade serous carcinoma.

Kuhn, Elisabetta; Wang, Tian-Li; Doberstein, Kai; Bahadirli-Talbott, Asli; Ayhan, Ayse; Sehdev, Ann Smith; Drapkin, Ronny; Kurman, Robert J; Shih, Ie-Ming.

Mod Pathol ; 29(10): 1254-61, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27443516

4.

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

Doberstein, Kai; Harter, Patrick N; Haberkorn, Uwe; Bretz, Niko P; Arnold, Bernd; Carretero, Rafael; Moldenhauer, Gerhard; Mittelbronn, Michel; Altevogt, Peter.

Int J Cancer ; 136(5): E326-39, 2015 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-25230579

5.

Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas.

Harter, Patrick N; Baumgarten, Peter; Zinke, Jenny; Schilling, Karl; Baader, Stefan; Hartmetz, Ann-Kathrin; Schittenhelm, Jens; Beschorner, Rudi; Liebner, Stefan; Schulte, Dorothea; Plate, Karl-Heinz; Gutwein, Paul; Korshunov, Andrey; Pfister, Stefan M; Jones, David T W; Doberstein, Kai; Mittelbronn, Michel.

Neuropathol Appl Neurobiol ; 41(2): 165-79, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25287489

6.

L1CAM is expressed in triple-negative breast cancers and is inversely correlated with androgen receptor.

Doberstein, Kai; Milde-Langosch, Karin; Bretz, Niko P; Schirmer, Uwe; Harari, Ayelet; Witzel, Isabell; Ben-Arie, Alon; Hubalek, Michael; Müller-Holzner, Elisabeth; Reinold, Susanne; Zeimet, Alain G; Altevogt, Peter; Fogel, Mina.

BMC Cancer ; 14: 958, 2014 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-25510351

7.

LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma.

Sato, Sho; Gillette, Michael; de Santiago, Pamela R; Kuhn, Eric; Burgess, Michael; Doucette, Kristen; Feng, Yi; Mendez-Dorantes, Carlos; Ippoliti, Paul J; Hobday, Sara; Mitchell, Marilyn A; Doberstein, Kai; Gysler, Stefan M; Hirsch, Michelle S; Schwartz, Lauren; Birrer, Michael J; Skates, Steven J; Burns, Kathleen H; Carr, Steven A; Drapkin, Ronny.

Sci Rep ; 13(1): 1537, 2023 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-36707610

8.

L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary.

Doberstein, Kai; Spivak, Rebecca; Reavis, Hunter D; Hooda, Jagmohan; Feng, Yi; Kroeger, Paul T; Stuckelberger, Sarah; Mills, Gordon B; Devins, Kyle M; Schwartz, Lauren E; Iwanicki, Marcin P; Fogel, Mina; Altevogt, Peter; Drapkin, Ronny.

Commun Biol ; 5(1): 1362, 2022 12 12.

Artigo em Inglês | MEDLINE | ID: mdl-36509990

9.

The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.

Doberstein, Kai; Pfeilschifter, Josef; Gutwein, Paul.

Carcinogenesis ; 32(11): 1713-23, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21880579

10.

L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells.

Doberstein, Kai; Wieland, Anja; Lee, Sophia B Boyoung; Blaheta, Roman A Alexander; Wedel, Steffen; Moch, Holger; Schraml, Peter; Pfeilschifter, Josef; Kristiansen, Glen; Gutwein, Paul.

Carcinogenesis ; 32(3): 262-70, 2011 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-21097529

11.

ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma.

Ungerer, Christopher; Doberstein, Kai; Bürger, Claudia; Hardt, Katja; Boehncke, Wolf-Henning; Böhm, Beate; Pfeilschifter, Josef; Dummer, Reinhard; Mihic-Probst, Daniela; Gutwein, Paul.

Biochem Biophys Res Commun ; 401(3): 363-9, 2010 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-20851104

12.

CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein.

Gutwein, Paul; Abdel-Bakky, Mohamed Sadek; Schramme, Anja; Doberstein, Kai; Kämpfer-Kolb, Nicole; Amann, Kerstin; Hauser, Ingeborg A; Obermüller, Nicholas; Bartel, Christine; Abdel-Aziz, Abdel-Aziz H; El Sayed, El Sayed M; Pfeilschifter, Josef.

Am J Pathol ; 174(6): 2061-72, 2009 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-19435795

13.

ADAM10 is expressed in human podocytes and found in urinary vesicles of patients with glomerular kidney diseases.

Gutwein, Paul; Schramme, Anja; Abdel-Bakky, Mohamed Sadek; Doberstein, Kai; Hauser, Ingeborg A; Ludwig, Andreas; Altevogt, Peter; Gauer, Stefan; Hillmann, Anja; Weide, Thomas; Jespersen, Christine; Eberhardt, Wolfgang; Pfeilschifter, Josef.

J Biomed Sci ; 17: 3, 2010 Jan 13.

Artigo em Inglês | MEDLINE | ID: mdl-20070888

14.

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy.

Gutwein, Paul; Abdel-Bakky, Mohamed Sadek; Doberstein, Kai; Schramme, Anja; Beckmann, Janet; Schaefer, Liliana; Amann, Kerstin; Doller, Anke; Kämpfer-Kolb, Nicole; Abdel-Aziz, Abdel-Aziz H; El Sayed, El Sayed M; Pfeilschifter, Josef.

J Cell Mol Med ; 13(9B): 3809-25, 2009 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-19426159

15.

Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma.

Gutwein, Paul; Schramme, Anja; Voss, Beren; Abdel-Bakky, Mohamed Sadek; Doberstein, Kai; Ludwig, Andreas; Altevogt, Peter; Hansmann, Martin-Leo; Moch, Holger; Kristiansen, Glen; Pfeilschifter, Josef.

Biochem Biophys Res Commun ; 380(2): 387-91, 2009 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-19250634

16.

Novel intra-tissue perfusion system for culturing thick liver tissue.

Khong, Yuet Mei; Zhang, Jing; Zhou, Sibo; Cheung, Christine; Doberstein, Kai; Samper, Victor; Yu, Hanry.

Tissue Eng ; 13(9): 2345-56, 2007 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-17708717

17.

miR-21-3p is a positive regulator of L1CAM in several human carcinomas.

Doberstein, Kai; Bretz, Niko P; Schirmer, Uwe; Fiegl, Heidi; Blaheta, Roman; Breunig, Christian; Müller-Holzner, Elisabeth; Reimer, Dan; Zeimet, Alain G; Altevogt, Peter.

Cancer Lett ; 354(2): 455-66, 2014 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-25149066

18.

Lack of CD24 expression in mice reduces the number of leukocytes in the colon.

Bretz, Niko P; Salnikov, Alexei V; Doberstein, Kai; Garbi, Natalio; Kloess, Volker; Joumaa, Safwan; Naumov, Inna; Boon, Louis; Moldenhauer, Gerhard; Arber, Nadir; Altevogt, Peter.

Immunol Lett ; 161(1): 140-8, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-24956310

19.

Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma.

Schirmer, Uwe; Doberstein, Kai; Rupp, Anne-Kathleen; Bretz, Niko P; Wuttig, Daniela; Kiefel, Helena; Breunig, Christian; Fiegl, Heidi; Müller-Holzner, Elisabeth; Zeillinger, Robert; Schuster, Eva; Zeimet, Alain G; Sültmann, Holger; Altevogt, Peter.

Oncotarget ; 5(2): 462-72, 2014 Jan 30.

Artigo em Inglês | MEDLINE | ID: mdl-24497324

20.

MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients.

Doberstein, Kai; Steinmeyer, Nico; Hartmetz, Ann-Kathrin; Eberhardt, Wolfgang; Mittelbronn, Michel; Harter, Patrick N; Juengel, Eva; Blaheta, Roman; Pfeilschifter, Josef; Gutwein, Paul.

Neoplasia ; 15(2): 218-30, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23441135

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