Detalhe da pesquisa
1.
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
Nature
; 535(7610): 148-52, 2016 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27362227
2.
Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours.
Br J Cancer
; 125(1): 28-37, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941878
3.
Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation.
PLoS Genet
; 12(7): e1006120, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27414415
4.
Identifying Nuclear Matrix-Attached DNA Across the Genome.
J Cell Physiol
; 232(6): 1295-1305, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27627025
5.
The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter.
Nucleic Acids Res
; 42(16): 10360-72, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25120271
6.
The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.
J Cell Physiol
; 230(11): 2683-94, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25808524
7.
Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFß1.
J Cell Biochem
; 116(9): 2098-108, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25808168
8.
A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation.
J Cell Sci
; 125(Pt 11): 2732-9, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22393235
9.
hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.
Cancer Cell Int
; 14: 73, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25120384
10.
Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes.
Proc Natl Acad Sci U S A
; 107(9): 4165-9, 2010 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20160071
11.
Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility.
Breast Cancer Res
; 12(5): R89, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-21029421
12.
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition.
Oncotarget
; 8(11): 17610-17627, 2017 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28407681
13.
A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors.
Clin Cancer Res
; 23(10): 2433-2441, 2017 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28432176
14.
Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes.
Mol Cancer Res
; 15(12): 1722-1732, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28851814
15.
The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation.
Oncotarget
; 7(25): 38270-38281, 2016 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27223259
16.
A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas.
Clin Cancer Res
; 22(23): 5696-5705, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27542767
17.
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes.
Nat Genet
; 47(2): 106-14, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25501392
18.
Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine.
Genome Med
; 6(1): 5, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24479672
19.
Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.
Genome Biol
; 15(3): R52, 2014 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24655370