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1.
Clin J Sport Med ; 32(3): 236-247, 2022 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-33797476

RESUMO

OBJECTIVE: The aim of this review is to provide a summary of the epidemiology, clinical presentation, pathophysiology, and treatment of traumatic brain injury in collision athletes, particularly those participating in American football. DATA SOURCES: A literature search was conducted using the PubMed/MEDLINE and Google Scholar databases for publications between 1990 and 2019. The following search phrases were used: "concussion," "professional athletes," "collision athletes," "mild traumatic brain injury," "severe traumatic brain injury," "management of concussion," "management of severe traumatic brain injury," and "chronic traumatic encephalopathy." Publications that did not present epidemiology, clinical presentation, pathophysiology, radiological evaluation, or management were omitted. Classic articles as per senior author recommendations were retrieved through reference review. RESULTS: The results of the literature review yielded 147 references: 21 articles discussing epidemiology, 16 discussing clinical presentation, 34 discussing etiology and pathophysiology, 10 discussing radiological evaluation, 34 articles for on-field management, and 32 articles for medical and surgical management. CONCLUSION: Traumatic brain injuries are frequent in professional collision athletes, and more severe injuries can have devastating and lasting consequences. Although sport-related concussions are well studied in professional American football, there is limited literature on the epidemiology and management of severe traumatic brain injuries. This article reviews the epidemiology, as well as the current practices in sideline evaluation, acute management, and surgical treatment of concussions and severe traumatic brain injury in professional collision athletes. Return-to-play decisions should be based on individual patient symptoms and recovery.


Assuntos
Traumatismos em Atletas , Concussão Encefálica , Lesões Encefálicas Traumáticas , Futebol Americano , Atletas , Traumatismos em Atletas/diagnóstico , Traumatismos em Atletas/epidemiologia , Traumatismos em Atletas/terapia , Concussão Encefálica/diagnóstico , Concussão Encefálica/epidemiologia , Concussão Encefálica/terapia , Lesões Encefálicas Traumáticas/epidemiologia , Lesões Encefálicas Traumáticas/terapia , Futebol Americano/lesões , Humanos
2.
J Surg Orthop Adv ; 31(4): 256-262, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36594985

RESUMO

This study evaluated the associations of demographics and social media (SM) usage on physician review websites for spine surgeons in New Jersey and Pennsylvania. Three physician rating websites were accessed to obtain training history, number of ratings/reviews, and overall rating (0-5). Surgeon web pages and publicly searchable SM accounts on Facebook (FB), Twitter (T), and/or Instagram (IG) were recorded. Of 246 spine surgeons included, 95.9% had a personal/institutional website while 12.2% were present on at least one SM platform. Physician age was inversely correlated with Healthgrades.com (HG), Vitals.com (V), and Google.com (G) ratings (p < 0.0001). Physicians with SM had higher ratings on HG (p = 0.006) and V (p = 0.006). Spine surgeons with SM received more ratings, comments, and higher scores than those without SM. All review sites agree that SM presence correlated with the number of ratings and comments across physician review websites, suggesting SM may influence patient feedback. (Journal of Surgical Orthopaedic Advances 31(4):256-262, 2022).


Assuntos
Ortopedia , Mídias Sociais , Cirurgiões , Humanos , Internet , Satisfação do Paciente , Listas de Espera
3.
J Pediatr Orthop ; 41(6): 385-388, 2021 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-34096556

RESUMO

BACKGROUND: Pediatric orthopaedic fellowship directors (FDs) have a valuable impact on the education of trainees and future leaders in the field. There is currently no research on the characteristics of pediatric orthopaedic FDs. METHODS: Programs were identified using the Pediatric Orthopaedic Society of North America fellowship directory. Operative, nonoperative, and specialty programs were included. Data was collected through Qualtrics survey, e-mail, telephone, and online searches. Variables included demographics (age, sex, race/ethnicity), Hirsch index (h-index) as a measure of research productivity, graduate education, residency and fellowship training, years of hire at current institution and as FD, and leadership roles. RESULTS: Fifty-five FDs were identified. The majority (49/55, 89%) were male and 77% (27/35) were Caucasian. The mean age at survey was 51.1±8.2 years. The mean h-index was 17.2. Older age correlated with higher h-index (r=0.48, P=0.0002). The average duration from fellowship graduation to FD appointment was 9.6±6.7 and 6.9±6.1 years from institutional hire. Sixteen FDs (29%) had additional graduate level degrees. Almost all (52/55, 95%) FDs completed orthopaedic surgery residencies and all graduated fellowship training. Twenty-nine percent (16/55) completed more than 1 fellowship. Most FDs (51/55, 93%) completed a fellowship in pediatric orthopaedic surgery. Ten FDs (18%) completed pediatric orthopaedic surgery fellowships that included spine-specific training. One-third of all current FDs were fellowship-trained at either Boston Children's Hospital (9/55, 16%) or Texas Scottish Rite Hospital for Children (9/55, 16%). CONCLUSIONS: Pediatric orthopaedic FDs are typically early-career to mid-career when appointed, with a strong research background. Nearly a third completed additional graduate degrees or multiple fellowships. Although male dominated, there are more female FDs leading pediatric orthopaedic programs compared with adult reconstruction, trauma, and spine fellowships. As fellowships continue to grow and diversify, this research will provide a baseline to determine changes in FD leadership.


Assuntos
Bolsas de Estudo/organização & administração , Liderança , Ortopedia/educação , Pediatria/educação , Diretores Médicos/estatística & dados numéricos , Adulto , Educação de Pós-Graduação em Medicina , Escolaridade , Feminino , Humanos , Internato e Residência , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , População Branca/estatística & dados numéricos
4.
J Arthroplasty ; 35(9): 2671-2675, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32507452

RESUMO

BACKGROUND: Fellowship directors (FDs) in adult reconstruction have a profound impact on current and future trainees within orthopedics. Our group sought to evaluate the shared characteristics among current adult reconstruction FDs to provide a framework for those aspiring to achieve this position and identify possible areas of improvement. METHODS: Fellowship programs were identified using the American Association of Hip and Knee Surgeons Directory. Data for each FD were gathered via electronic mail, telephone, curriculum vitae, and online searches. Demographic information collected included age, gender, ethnicity, residency/fellowship training, residency/fellowship graduation year, year hired by current institution, time since training completion until FD appointment, length in FD role, and Scopus H-index. RESULTS: Information was gathered for 94 FDs. Of these, 100% were males; 80.6% were Caucasian, 12.90% were Asian American, 5.38% were Hispanic, and 1.08% were African American. The average age (52.6 years old), H-index (16.54), year of residency (2000) and fellowship (2001) graduation, and time since training until FD appointment (9.55 years) were analyzed. The top training programs to produce future FDs were Mayo Clinic (residency) and Harvard University (fellowship). CONCLUSION: Adult reconstruction FDs are frequently distinguished by their level of research productivity and experience, but certainly more demographic diversity is needed within this cohort. Specific training programs may inherently have a vital role in the development of individuals for future leadership positions. These developments could be a result of unique features inherent to the training programs or because of a subset of applicants who pursue specific programs with aspirations of subsequent leadership opportunities.


Assuntos
Internato e Residência , Procedimentos Ortopédicos , Ortopedia , Adulto , Bolsas de Estudo , Feminino , Humanos , Liderança , Masculino , Pessoa de Meia-Idade , Ortopedia/educação , Estados Unidos
5.
J Arthroplasty ; 34(5): 959-964.e1, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30814026

RESUMO

BACKGROUND: Sleep apnea (SA) negatively affects bone mineralization, cognition, and immunity. There is paucity in the literature regarding the impact of SA on total joint arthroplasty (TJA). The purpose of this study is to compare complications in patients with and without SA undergoing either total knee (TKA) or total hip arthroplasty (THA). METHODS: A retrospective review from 2005 to 2014 was conducted using the Medicare Standard Analytical Files. Patients with and without SA on the day of the primary TJA were queried using the International Classification of Diseases, ninth revision codes. Patients were matched by age, gender, Charlson Comorbidity Index), and body mass index. Patients were followed for 2 years after their surgery. Ninety-day medical complications, complications related to implant, readmission rates, length of stay, and 1-year mortality were quantified and compared. Logistic regression was used to calculate odds ratios (OR) with their respective 95% confidence interval and P values. RESULTS: After the random matching process there were 529,240 patients (female = 271,656, male = 252,106, unknown = 5478) with (TKA = 189,968, THA = 74,652) and without (TKA = 189,968, THA = 74,652) SA who underwent primary TJA between 2005 and 2014. Patients with SA had greater odds of developing medical complications following TKA (OR 3.71) or THA (OR 2.48). CONCLUSION: The study illustrates an increased risk of developing postoperative complications in patients with SA following primary TJA. Surgeons should educate patients on these adverse effects and encourage the use of continuous positive airway pressure which has been shown to mitigate many postoperative complications.


Assuntos
Artroplastia de Quadril/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Osteoartrite/cirurgia , Síndromes da Apneia do Sono/complicações , Idoso , Artroplastia de Quadril/economia , Artroplastia do Joelho/economia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Osteoartrite/complicações , Osteoartrite/economia , Estudos Retrospectivos , Síndromes da Apneia do Sono/economia , Estados Unidos
6.
J Arthroplasty ; 33(8): 2627-2630, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29691178

RESUMO

BACKGROUND: High altitudes lead to physiological changes that may predispose to venous thromboembolisms (VTEs) including deep vein thrombosis and pulmonary embolism (PE). No prior study has evaluated if there is also a higher risk of VTEs for total hip arthroplasties (THAs) performed at higher elevations. The purpose of this retrospective study was to identify if undergoing THA at a higher altitude center (>4000 feet above sea level) is an independent risk factor for a postoperative VTE. METHODS: A thorough evaluation of the Pearl Diver Database was performed for patients undergoing THAs from 2005 to 2014. Using International Classification of Diseases Ninth Edition facilitated in ascertaining patients who underwent THA. Using the ZIP codes of the hospitals where the procedure occurred, we separated our groups into high-altitude (>4000 ft) and low-altitude (<100 ft) groups. RESULTS: In the first 30 postoperative days, patients undergoing THA at a higher altitude experienced a significantly higher rate of PEs (odds ratio, 1.74; P = .003) when compared to similar patients at lower altitudes. This trend was also present for PE (odds ratio, 1.59; P < .001) at 90 days postoperatively. CONCLUSION: THAs performed at higher altitudes (>4000 feet) have a higher rate of acute postoperative PEs in the first 30 days and also 90 days postoperatively when compared to matched patients receiving the same surgery at a lower altitude (<100 feet). THA patients at high altitude should be counseled on these increased risks; however, owing to retrospective nature and confounders, prospective studies are necessary to explore this outcome in more detail.


Assuntos
Altitude , Artroplastia de Quadril/efeitos adversos , Embolia Pulmonar/epidemiologia , Embolia Pulmonar/etiologia , Tromboembolia Venosa/epidemiologia , Tromboembolia Venosa/etiologia , Trombose Venosa/epidemiologia , Trombose Venosa/etiologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Geografia , Hospitais , Humanos , Masculino , Medicare , Pessoa de Meia-Idade , Razão de Chances , Período Pós-Operatório , Estudos Prospectivos , Estudos Retrospectivos , Fatores de Risco , Estados Unidos
7.
Pediatr Emerg Care ; 33(5): 325-328, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28398941

RESUMO

OBJECTIVE: The aim of this study was to identify the types of pediatric orthopedic extremity fractures that are sustained as a result of hoverboard (self-balancing, self-propelling, 2-wheeled boards) use. METHODS: We performed a retrospective review of all orthopedic consultations from the emergency department at our institution from December 1 to 31, 2015. Data was collected on the injury mechanism, fracture location, management, and patient characteristics including sex, age, and hand dominance. RESULTS: A total of 307 patients with acute extremity injuries were evaluated for a 31-day period. Hoverboard use was identified as the mechanism of injury in 36 patients with 36 fractures (11.7%). The mean age of these 36 patients was 11 years (range, 4-17 y), with most being male (69.4%). There were 35 upper extremity fractures and 1 lower extremity fracture. Eight (22.9%) of the 36 hoverboard patients required closed reduction in the emergency department either under conscious sedation or hematoma block performed with local anesthetic. Four patients (11.1%) required operative treatment. CONCLUSIONS: The overall incidence of extremity fractures due to hoverboard riding seen in our emergency department during the holiday season was relatively high compared with other common childhood activities. The vast majority of these fractures involved the upper extremities. A moderate percentage of these injuries required closed reduction in the emergency department or surgical treatment. Additional studies examining the use of protective equipment while riding hoverboards, time from initial hoverboard use to injury, supervision, and the cost of treating these injuries should be conducted to further elucidate the nature of these injuries and work toward prevention.


Assuntos
Acidentes por Quedas/prevenção & controle , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/epidemiologia , Veículos Off-Road/estatística & dados numéricos , Patinação/lesões , Acidentes por Quedas/estatística & dados numéricos , Adolescente , Criança , Pré-Escolar , Redução Fechada/métodos , Sedação Consciente , Serviço Hospitalar de Emergência/estatística & dados numéricos , Feminino , Fraturas Ósseas/cirurgia , Humanos , Incidência , Masculino , Estudos Retrospectivos , Risco , Estações do Ano , Patinação/estatística & dados numéricos , Estados Unidos/epidemiologia
8.
Arch Orthop Trauma Surg ; 137(12): 1615-1621, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28861676

RESUMO

PURPOSE: We intend to describe and analyze the spectrum of upper extremity injuries that arises from both accidental and intentional machete injuries with a focus on associated complications and comorbidities. This review is the first from a United States institution, and the only from a designated level 1 trauma center. METHODS: A retrospective review of machete related upper extremity injuries admitted to a level 1 trauma center from 2008 to 2016. The following data was collected on admitted patients: demographics, mechanism of injury, surgical management, and complications. We assessed the data with Pearson Chi square analysis. RESULTS: This cohort consisted of 48 patients (mean = 42 ± 13 years old); the majority were men (96%) involved in an assault (81%). These patients had a high rate of documented psychiatric history, substance and tobacco abuse, and being underinsured. Patient follow-up was extremely variable: 75% of patients presented for follow-up care (mean = 149 ± 344 days; range 8-1846 days). 44% had complications (i.e., infection, tendon rupture, nerve palsy). We identified no associations when examining follow-up rates or complication rates regarding patient comorbidities, insurance status, mechanism of injury, or the need for a nerve, artery, or tendon repair. Patients with current tobacco use did have an increased risk for infection. The majority (52%) of injuries occurred on the ulnar side of the forearm and to the non-dominant extremity (66%). Patients assaulted by machetes are significantly more likely to have a history of psychiatric illness, substance abuse, tobacco use, and are more likely to be underinsured compared to those with accidental machete injuries. CONCLUSIONS: While machete injuries may be uncommon in most areas of the United States, physicians should give special attention to the patient comorbidities as many of these patients have complex medical and social issues which could complicate attempts of appropriate treatment. LEVEL OF EVIDENCE: IV; Prognostic Study.


Assuntos
Extremidade Superior/lesões , Ferimentos Perfurantes/complicações , Adolescente , Adulto , Idoso , Artérias/lesões , Feminino , Humanos , Infecções/etiologia , Masculino , Pessoa de Meia-Idade , Traumatismos dos Nervos Periféricos/etiologia , Estudos Retrospectivos , Fatores de Risco , Traumatismos dos Tendões/etiologia , Centros de Traumatologia , Extremidade Superior/irrigação sanguínea , Extremidade Superior/inervação , Violência , Adulto Jovem
9.
Global Spine J ; : 21925682241279526, 2024 Aug 28.
Artigo em Inglês | MEDLINE | ID: mdl-39197439

RESUMO

STUDY DESIGN: Systematic Review and meta-analysis. OBJECTIVE: To conduct an updated systematic review and meta-analysis of complications associated with different anterior fusion techniques/approaches and adjuvant resources (i.e., computed tomography angiography (CTA), rhBMP-2, and access surgeons). METHODS: A systematic review was conducted from 1/1/2014-4/1/2024 for studies evaluating the incidence of complications associated with anterior lumbar procedures. Comparisons of complications were made between surgical approach, use of CTA, rhBMP-2, and access surgeons. Meta-analyses were conducted using a generalized linear mixed model. RESULTS: 54 studies were included in the final analysis with 8066 patients and an average follow-up of 31.2 months. The overall complication rate associated with anterior lumbar surgery was 13.1%, including an intraoperative complication rate of 3.8%, postoperative complication rate of 7.4%, infection rate of 1.5%, and reoperation rate of 1.7%. Forest plot analysis showed no significant difference in overall complication rates between open and mini-open techniques, although mini-open techniques were associated with lower overall reoperation rates. The use of CTA was associated with an increase in intraoperative and overall complications, and the use of an access surgeon was associated with a decreased risk of reoperation. The use of rhBMP-2 was not associated with overall complication risk. CONCLUSIONS: While anterior lumbar surgery provides numerous benefits, surgeons and patients alike should be aware of the complication and safety profile prior to surgery. High quality studies are warranted to help elucidate the true benefit of certain techniques and adjuvant resources in reducing complications.

10.
World Neurosurg ; 172: e250-e255, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36610642

RESUMO

OBJECTIVE: The Internet is a source of health information for patients. Quality of information available to patients is varied and uncontrolled. Physicians should be familiar with the overall quality of the information. This review provides an evaluation of YouTube's current patient accessible health information on the topic of lumbar disc herniation (LDH). METHODS: YouTube was queried using 3 different search strings: (1) "disc herniation", (2) "lumbar disc herniation", or (3) "lower back disc herniation". Video duplicates, non-English, or those that contained no audio or were not relevant to LDH were excluded. The first 50 videos per search string were evaluated. Two reviewers independently assessed videos. Parameters included duration, upload date, number of views, number of likes, views per day, and likes per day. A scoring system was used to grade the videos for their performance on diagnosis and treatment of LDH. RESULTS: The first 50 videos produced a total number of hits of 50,500, 29,100, and 22,100, respectively. Strong agreement, assessed using intraclass correlation coefficient (ICC), was demonstrated between readers for both diagnostic scores (ICC 0.921, 95% CI 0.866-0.953) and treatment scores (ICC 0.916, 95% CI 0.855-0.951). Educational Physician videos had significantly greater diagnostic and treatment scores compared to non-physician videos (9.54 vs. 7.05, P = 0.048, and 6.53 vs. 5.3, P = 0.004). CONCLUSIONS: YouTube videos pertaining to LDH were found to have low overall quality. Physicians should be cognizant about information sources readily available to patients as they may influence patient expectations and preconceptions.


Assuntos
Mídias Sociais , Humanos , Fonte de Informação , Gravação em Vídeo , Pacientes , Disseminação de Informação
11.
Iowa Orthop J ; 43(1): 23-29, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37383866

RESUMO

Background: The COVID-19 pandemic and its effects on the orthopaedic match process are yet to be fully understood and should be explored. We hypothesize that the cancellation of away rotations due to the COVID-19 pandemic would decrease the variability of where students matched into orthopaedic residency compared to pre-pandemic years. Methods: Accredited orthopaedic programs were collected from the Accreditation Council for Graduate Medical Education (ACGME) database. Rosters of orthopaedic residency classes for the years 2019, 2020, and 2021 were compiled across all orthopaedic programs in the United States. Data collection for the incoming 2021 orthopaedic surgery residents was carried out by reviewing each program's website, Instagram, and Twitter. Results: Data for the incoming orthopaedic surgery residents from the 2021 National Residency Match Program (NRMP) were collected. 25.7% of incoming residents matched at their home institution. Data collection for the 2020 and 2019 orthopaedic residency classes yielded 19.2% and 19.5% home institution match rates, respectively. When examining likelihood to match into an orthopaedic residency program in ones own's state, we found that in the 2021 match cycle, 39.3% of applicants matched within their state, while 34.3% and 33.4% of incoming residents matched in 2020 and 2019, respectively. Conclusion: To keep our patients and staff safe, visiting externship rotations were suspended in the 2021 Match cycle. As we continue to navigate the shifting waters of the COVID-19 pandemic, it is important to understand how our choices affect the dynamics of applying into residency training and beyond. This study demonstrates that a higher percentage of applicants that matched into orthopaedic residency remained at their home program compared to the previous two years before the pandemic. This indicates that programs tended to rank their home applicants, and that applicants tended to rank their home programs, higher than those that were less familiar. Level of Evidence: IV.


Assuntos
COVID-19 , Internato e Residência , Procedimentos Ortopédicos , Humanos , Pandemias , Acreditação
12.
Hand (N Y) ; 18(6): 1044-1050, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-35130763

RESUMO

BACKGROUND: Fellowship directors (FDs) influence the future of trainees in the field of hand surgery. Currently, there are no studies that analyze the demographic background, institutional training, and academic experience of hand surgery FDs. This study aims to serve as a framework to understand the landscape of current leadership positions in hand surgery education and to identify opportunities to improve FD diversity. METHODS: The American Society for Surgery of the Hand Fellowship Directory was reviewed to include all hand surgery fellowships in the United States. Collected demographic information regarding FDs included age, sex, ethnicity, residency/fellowship training, residency/fellowship graduation year, year hired by current institution, time since training completion until FD appointment, length in FD role, and H-index. RESULTS: Of the 90 FDs included, 86.7% were men and 71.4% self-reported as Caucasian. The average H-index was 13.98 and significantly correlated with age and duration as FD; 71.1% of FDs were trained in orthopedic surgery. The most attended residency program was the University of Pennsylvania; Mayo Clinic and Harvard University were the most represented fellowship programs. CONCLUSION: This review reveals specific trends in demographic backgrounds, institutional training, and academic experiences among current FDs in hand surgery. Our observations, such as racial/ethnic and sex disparities, may offer opportunities to improve the representation of the communities these physicians serve. In addition, the trends described in this study provide objective data among current hand surgery FDs and could serve as a guide for individuals who desire academic leadership roles.


Assuntos
Internato e Residência , Ortopedia , Masculino , Humanos , Estados Unidos , Feminino , Bolsas de Estudo , Liderança , Mãos/cirurgia , Ortopedia/educação
13.
Clin Spine Surg ; 35(1): E68-E76, 2022 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-34379614

RESUMO

Cervical spondylotic myelopathy (CSM) develops insidiously as degenerative changes of the cervical spine impact the spinal cord. Unfortunately, CSM is a form of spinal cord injury in older patients that often experiences delayed treatment. This summary evaluates the pathophysiology, natural history, diagnosis, and current management of CSM. Frequently, patients do not appreciate or correlate their symptomatology with cervical spine disease, and those with radiographic findings may be clinically asymptomatic. Providers should remember the classic symptoms of CSM-poor hand dexterity, new unsteady gait patterns, new onset and progressive difficulty with motor skills. An magnetic resonance imaging is required in patients with suspected CSM, but computerized tomography myelography is an alternative in patients with implants as contraindications to magnetic resonance imaging. The management of those with CSM has continued to be a controversial topic. In general, patients with incidental findings of cervical cord compression that are asymptomatic can be managed conservatively. Those with daily moderate-severe disease that significantly affects activities of daily living should be treated operatively.


Assuntos
Compressão da Medula Espinal , Doenças da Medula Espinal , Espondilose , Atividades Cotidianas , Idoso , Vértebras Cervicais/diagnóstico por imagem , Vértebras Cervicais/patologia , Vértebras Cervicais/cirurgia , Humanos , Imageamento por Ressonância Magnética/métodos , Doenças da Medula Espinal/diagnóstico por imagem , Doenças da Medula Espinal/cirurgia , Espondilose/diagnóstico por imagem , Espondilose/cirurgia
14.
World Neurosurg ; 158: 182-188, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34875392

RESUMO

BACKGROUND: Spinal fusion is the mainstay treatment for various spinal conditions ranging from lumbar and cervical stenosis to degenerative spondylolisthesis as well as extensive deformity corrections. A new emerging category of allograft is cellular bone matrices (CBMs), which take allogeneic mesenchymal stem cells and incorporate them into an osteoconductive and osteoinductive matrix. This study reviewed the current spinal fusion options and new emerging treatment options. METHODS: Articles were searched using PubMed. The search included English publications since January 1, 2014, using the search terms "cellular bone matrix," "mesenchymal stem cells spinal fusion," "spinal arthrodesis AND mesenchymal stem cells," and "spine fusion AND cellular bone matrix." RESULTS: Spinal fusion is accomplished through the use of allografts, autografts, and bone graft substitutes in combination or alone. An emerging category of allograft is CBMs, in which an osteoconductive and osteoinductive matrix is filled with mesenchymal stem cells. Studies demonstrate that CBMs have achieved equivalent or better fusion rates compared with traditional options for anterior cervical discectomy and fusions and posterolateral lumbar fusions; however, the studies have been retrospective and lacking control groups and therefore not ideal. CONCLUSIONS: Many treatment options have been successfully used in spinal fusion. Newer allografts such as CBMs have shown promising results in both animal and clinical studies. Further research is needed to determine the therapeutic dose of mesenchymal stem cells delivered within CBMs.


Assuntos
Substitutos Ósseos , Células-Tronco Mesenquimais , Doenças da Coluna Vertebral , Fusão Vertebral , Animais , Matriz Óssea/transplante , Substitutos Ósseos/uso terapêutico , Transplante Ósseo/métodos , Vértebras Lombares/cirurgia , Estudos Retrospectivos , Doenças da Coluna Vertebral/tratamento farmacológico , Fusão Vertebral/métodos
15.
Clin Spine Surg ; 35(9): 354-362, 2022 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-34923504

RESUMO

A symptomatic postoperative epidural hematoma (SPEH) in the lumbar spine is a complication with variable presentation and the potential to rapidly cause an irrecoverable neurological injury. Significant heterogeneity exists among current case series reporting SPEH in the literature. This review attempts to clarify the known incidence, risk factors, and management pearls. Currently, literature does not support the efficacy of subfascial drains in reducing the incidence of SPEHs and possibly suggests that medication for thromboembolism prophylaxis may increase risk. Acute back pain and progressing lower extremity motor weakness are the most common presenting symptoms of SPEH. Magnetic resonance imaging is the mainstay of diagnostic imaging necessary to confirm the diagnosis, but if not acutely available, an immediate return to the operative theater for exploration without advanced imaging is justified. Treatment of a SPEH consists of emergent hematoma evacuation as a delay in repeat surgery has a deleterious effect on neurological recovery. Outcomes are poorly defined, though a significant portion of patients will have lasting neurological impairments even when appropriately recognized and managed.


Assuntos
Hematoma Epidural Espinal , Complicações Pós-Operatórias , Humanos , Complicações Pós-Operatórias/etiologia , Hematoma Epidural Espinal/etiologia , Coluna Vertebral/cirurgia , Vértebras Lombares/patologia , Região Lombossacral/patologia , Período Pós-Operatório
16.
Surg Infect (Larchmt) ; 23(4): 364-371, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35262398

RESUMO

Background: Previous literature has associated increased body mass index (BMI) with risk of surgical site infection (SSI) after posterior cervical fusion (PCF) surgery. However, few studies have examined the association between local adiposity and risk of SSI, re-admission, and re-operation after PCF. Local adiposity is easily measured on pre-operative magnetic resonance imaging (MRI) and may act as a more accurate predictor compared with BMI. Patients and Methods: Subjects undergoing PCF from 2013-2018 at a single institution were identified retrospectively. Posterior cervical subcutaneous fat thickness, paraspinal muscle thickness, and lamina-to-skin distance measurements were obtained from computed tomography (CT) or MRI scans. Subjects with active infection, malignancy, or revision procedures were excluded. Results: Two hundred five patients were included with 20 developing SSIs. Subjects with SSIs had a longer fusion construct (4.90 vs. 3.71 levels; p = 0.001), higher Elixhauser comorbidity index (ECI; 2.05 vs. 1.34; p = 0.045), had a history of diabetes mellitus (30% vs. 10.8%; p = 0.026), higher subcutaneous fat thickness (30.5 vs. 23.6 mm; p = 0.013), and higher lamina-to-skin distance (66.4 vs. 57.9 mm; p = 0.027). Subcutaneous fat thickness (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01-1.10]; p = 0.026) and lamina-to-skin distance (OR, 1.05; 95% CI, 1.01-1.09]; p = 0.014) were associated with SSI in multivariable analysis. A subcutaneous fat thickness cutoff value of 23.2 mm had 90% sensitivity and 54.1% specificity for prediction of SSI. There was no association need for re-admission or re-operation. Conclusions: Increased posterior cervical fat may increase the risk of SSI after PCF. Pre-operative advanced imaging may be a valuable tool for assisting with patient counseling, optimization, and risk stratification.


Assuntos
Doenças da Coluna Vertebral , Fusão Vertebral , Humanos , Obesidade/complicações , Estudos Retrospectivos , Fatores de Risco , Doenças da Coluna Vertebral/cirurgia , Fusão Vertebral/efeitos adversos , Fusão Vertebral/métodos , Gordura Subcutânea/diagnóstico por imagem , Infecção da Ferida Cirúrgica/complicações , Infecção da Ferida Cirúrgica/epidemiologia
17.
World Neurosurg ; 160: e537-e548, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35085804

RESUMO

OBJECTIVE: The aim of this study was to assess rates of adjacent segment degeneration (ASDeg), adjacent segment disease (ASDis), and reoperation rates as a result of adjacent segment pathology in patients who have undergone anterior cervical discectomy and fusion (ACDF) versus cervical disc arthroplasty (CDA). METHODS: A comprehensive search of randomized controlled trials was performed in PubMed from 2012 to 2019. Relevant studies included were assessed for quality using the Cochrane Beck Review Group guidelines. Rates of ASDeg, ASDis, and reoperation because of adjacent segment pathology were extracted and included in the final analysis. A random-effects and fixed-effects model was run among studies that showed high and low heterogeneity, respectively. RESULTS: A total of 19 studies were included in the final analysis, comprising 4655 patients. Overall, ACDFs reported significantly higher rates of ASDeg (19.7% vs. 14.4%; P < 0.001), ASDis (6.1% vs. 3.8%; P < 0.001), and reoperation rates (6.1% vs. 3.1%; P < 0.001) compared with CDAs, which was further corroborated in fixed-effects analysis. When stratified by length of follow-up, a significant difference was seen in ASDeg, ASDis, and reoperation rates of studies with follow-up of 12-48 months versus >48 months, with the exception of ASDeg rates in the CDA cohort. CONCLUSIONS: Our study shows CDA results in significantly lower ASDeg, ASDis, and reoperation rates. Although CDA may be a viable alternative to ACDF, further long-term studies are warranted to ensure consistency and establish longevity of our findings.


Assuntos
Degeneração do Disco Intervertebral , Fusão Vertebral , Artroplastia/métodos , Vértebras Cervicais/cirurgia , Discotomia/métodos , Humanos , Incidência , Degeneração do Disco Intervertebral/epidemiologia , Degeneração do Disco Intervertebral/etiologia , Degeneração do Disco Intervertebral/cirurgia , Ensaios Clínicos Controlados Aleatórios como Assunto , Fusão Vertebral/métodos
18.
Clin Spine Surg ; 35(6): 241-248, 2022 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-34379610

RESUMO

Sports-related acute cervical trauma and spinal cord injury (SCI) represent a rare but devastating potential complication of collision sport injuries. Currently, there is debate on appropriate management protocols and return-to-play guidelines in professional collision athletes following cervical trauma. While cervical muscle strains and sprains are among the most common injuries sustained by collision athletes, the life-changing effects of severe neurological sequelae (ie, quadriplegia and paraplegia) from fractures and SCIs require increased attention and care. Appropriate on-field management and subsequent transfer/workup at an experienced trauma/SCI center is necessary for optimal patient care, prevention of injury exacerbation, and improvement in outcomes. This review discusses the epidemiology, pathophysiology, clinical presentation, immediate/long-term management, and current return-to-play recommendations of athletes who suffer cervical trauma and SCI.


Assuntos
Traumatismos em Atletas , Traumatismos da Medula Espinal , Traumatismos da Coluna Vertebral , Atletas , Traumatismos em Atletas/complicações , Traumatismos em Atletas/terapia , Vértebras Cervicais/lesões , Humanos , Traumatismos da Medula Espinal/complicações , Traumatismos da Medula Espinal/terapia , Traumatismos da Coluna Vertebral/etiologia
19.
Urol Res ; 39(2): 141-6, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20924571

RESUMO

Although the 36-Item Short-Form General Health Survey (SF-36) has been utilized to assess quality of life (QoL) in cross-sectional studies, no longitudinal studies have evaluated this instrument in stone formers. Hence, we evaluated the performance of the SF-36 over time in a group of stone formers. From January to May 2007, the SF-36 was administered by independent interviewers to 155 patients with a history of stones, and 96 individuals subsequently completed a second questionnaire at a median interval of 18 months (10.3-28.5 months). Subjects were asked to report changes in stone status, interval procedures, and significant non-stone related changes. Changes in individual and composite scores of SF-36 were compared. Among the 96 patients who completed two SF-36 surveys, 75 patients denied experiencing a stone episode within the month preceding their initial or follow-up SF-36 form. No statistically significant differences in any of the SF-36 domains or the aggregate physical or mental health composite scores over time were noted in these patients. A total of 18 patients reported a stone event within the month preceding completion of the initial questionnaire but no stone event prior to the follow-up survey. No clinically or statistically significant changes in any of the SF-36 domains between the first and follow-up questionnaire were seen among these 18 patients. The results show the stability of the SF-36 over time in patients with no change in their stone status. However, the absence of significant changes in the SF-36 despite a change in stone status suggests that the SF-36 may not be an adequate tool to monitor quality of life over time in stone patients. Validated, disease-specific questionnaires are needed to facilitate comparison of treatment strategies for stone disease.


Assuntos
Cálculos Renais/fisiopatologia , Cálculos Renais/psicologia , Qualidade de Vida , Inquéritos e Questionários , Adulto , Idoso , Estudos de Coortes , Feminino , Nível de Saúde , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Fatores de Tempo , Estados Unidos
20.
Front Surg ; 8: 642972, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34291076

RESUMO

Incidental durotomies, or dural tears, can be very difficult and time consuming to repair properly when they are encountered in confined spaces. A novel dural repair device was developed to address these situations. In this paper, the novel device was assessed against the use of traditional tools and techniques for dural repairs in two independent studies using an intricate clinical simulation model. The aim was to examine the results of the two assessments and link the outcomes to the clinical use of the novel device in the operating room. The novel device outperformed conventional techniques as measured by dural repair time, CSF leak pressure and nerve root avoidance in the simulation. The results were generally replicable clinically, however, numerous additional clinical scenarios were also encountered that the simulation model was unable to capture due to various inherent limitations. The simulation model design, potential contributors to watertightness, clinical experiences, and limitation are discussed.

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