Detalhe da pesquisa
1.
Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane.
J Neurosci
; 43(13): 2222-2241, 2023 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36868853
2.
Human α6ß4 Nicotinic Acetylcholine Receptor: Heterologous Expression and Agonist Behavior Provide Insights into the Immediate Binding Site.
Mol Pharmacol
; 103(6): 339-347, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37001996
3.
Characterization of Binding Site Interactions and Selectivity Principles in the α3ß4 Nicotinic Acetylcholine Receptor.
J Am Chem Soc
; 144(35): 16101-16117, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36006801
4.
Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids.
J Am Chem Soc
; 144(19): 8480-8486, 2022 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35446570
5.
Binding Interactions of NS6740, a Silent Agonist of the α7 Nicotinic Acetylcholine Receptor.
Mol Pharmacol
; 96(2): 212-218, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175182
6.
A triad of residues is functionally transferrable between 5-HT3 serotonin receptors and nicotinic acetylcholine receptors.
J Biol Chem
; 293(8): 2903-2914, 2018 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29298898
7.
Probing Binding Interactions of Cytisine Derivatives to the α4ß2 Nicotinic Acetylcholine Receptor.
J Am Chem Soc
; 141(40): 15840-15849, 2019 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31518499
8.
Probing Proline Residues in the Prokaryotic Ligand-Gated Ion Channel, ELIC.
Biochemistry
; 57(27): 4036-4043, 2018 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29927250
9.
Probing for and Quantifying Agonist Hydrogen Bonds in α6ß2 Nicotinic Acetylcholine Receptors.
Biochemistry
; 56(13): 1836-1840, 2017 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28287260
10.
Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors.
J Biol Chem
; 291(12): 6272-80, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668320
11.
A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock.
J Am Chem Soc
; 139(13): 4655-4658, 2017 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28324654
12.
Mechanistic Studies of the Photoinduced Quinone Trimethyl Lock Decaging Process.
J Am Chem Soc
; 139(13): 4729-4736, 2017 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199106
13.
Photoactivation of an Acid-Sensitive Ion Channel Associated with Vision and Pain.
Chembiochem
; 17(14): 1323-7, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27123791
14.
Cation-π interactions: computational analyses of the aromatic box motif and the fluorination strategy for experimental evaluation.
Phys Chem Chem Phys
; 17(43): 29262-70, 2015 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26467787
15.
Nicotine binding to brain receptors requires a strong cation-pi interaction.
Nature
; 458(7237): 534-7, 2009 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19252481
16.
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines.
Proc Natl Acad Sci U S A
; 109(44): E3028-34, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035248
17.
Subtype-specific mechanisms for functional interaction between α6ß4* nicotinic acetylcholine receptors and P2X receptors.
Mol Pharmacol
; 86(3): 263-74, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24966348
18.
Binding interactions with the complementary subunit of nicotinic receptors.
J Biol Chem
; 288(10): 6991-7, 2013 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23349463
19.
In vivo incorporation of non-canonical amino acids by using the chemical aminoacylation strategy: a broadly applicable mechanistic tool.
Chembiochem
; 15(12): 1710-20, 2014 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24990307
20.
The cation-π interaction.
Acc Chem Res
; 46(4): 885-93, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23214924