Detalhe da pesquisa
1.
Rational design of a new antibiotic class for drug-resistant infections.
Nature
; 597(7878): 698-702, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34526714
2.
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models.
Antimicrob Agents Chemother
; 68(3): e0139423, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38289076
3.
Pharmacodynamic evaluation of ceftriaxone single-dose therapy (0.125-1 g) to eradicate ceftriaxone-susceptible and ceftriaxone-resistant Neisseria gonorrhoeae strains in a hollow fibre infection model for gonorrhoea.
J Antimicrob Chemother
; 79(5): 1006-1013, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38497988
4.
Individual Components of Polymyxin B Modeled via Population Pharmacokinetics to Design Humanized Dosage Regimens for a Bloodstream and Lung Infection Model in Immune-Competent Mice.
Antimicrob Agents Chemother
; 67(5): e0019723, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37022153
5.
Combination Therapy to Kill Mycobacterium tuberculosis in Its Nonreplicating Persister Phenotype.
Antimicrob Agents Chemother
; 66(10): e0069522, 2022 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36165631
6.
Vancomycin Area Under the Curve-Guided Dosing and Monitoring for Adult and Pediatric Patients With Suspected or Documented Serious Methicillin-Resistant Staphylococcus aureus Infections: Putting the Safety of Our Patients First.
Clin Infect Dis
; 72(9): 1497-1501, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740042
7.
"One-Two Punch": Synergistic ß-Lactam Combinations for Mycobacterium abscessus and Target Redundancy in the Inhibition of Peptidoglycan Synthesis Enzymes.
Clin Infect Dis
; 73(8): 1532-1536, 2021 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34113990
8.
Building Optimal Three-Drug Combination Chemotherapy Regimens To Eradicate Mycobacterium tuberculosis in Its Slow-Growth Acid Phase.
Antimicrob Agents Chemother
; 65(10): e0069321, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34339275
9.
The case for precision dosing: medical conservatism does not justify inaction.
J Antimicrob Chemother
; 76(7): 1661-1665, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33843994
10.
Development of New Antimicrobials for Urogenital Gonorrhea Therapy: Clinical Trial Design Considerations.
Clin Infect Dis
; 70(7): 1495-1500, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31538646
11.
Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-ß-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253209
12.
Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the United States Committee on Antimicrobial Susceptibility Testing (USCAST).
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31767718
13.
First Penicillin-Binding Protein Occupancy Patterns for 15 ß-Lactams and ß-Lactamase Inhibitors in Mycobacterium abscessus.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106266
14.
Methodological features of clinical pharmacokinetic-pharmacodynamic studies of antibacterials and antifungals: a systematic review.
J Antimicrob Chemother
; 75(6): 1374-1389, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32083674
15.
Ceftazidime-Avibactam in Combination With Fosfomycin: A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa.
J Infect Dis
; 220(4): 666-676, 2019 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31099835
16.
Effect of Moxifloxacin plus Pretomanid against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay.
Antimicrob Agents Chemother
; 63(1)2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30397058
17.
Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833428
18.
GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.
Antimicrob Agents Chemother
; 63(12)2019 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548183
19.
Comparable Efficacy and Better Safety of Double ß-Lactam Combination Therapy versus ßLactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30988147
20.
In vitro antimicrobial combination testing of and evolution of resistance to the first-in-class spiropyrimidinetrione zoliflodacin combined with six therapeutically relevant antimicrobials for Neisseria gonorrhoeae.
J Antimicrob Chemother
; 74(12): 3521-3529, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31730160