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1.
J Fr Ophtalmol ; 5(11): 727-32, 1982.
Artigo em Francês | MEDLINE | ID: mdl-6818269

RESUMO

A randomized double-blind trial was conducted in 143 out-patients with allergic conjunctivitis (281 eyes). Active sodium cromoglycate collyre was compared with placebo in parallel groups over a four-week period. Highly significant advantage for active drug was demonstrated for subjective and objective symptoms as well as for overall assessment by patients and physicians. Results were compared with international data concerning this well-known anti-allergic compound.


Assuntos
Conjuntivite/tratamento farmacológico , Cromolina Sódica/uso terapêutico , Hipersensibilidade/tratamento farmacológico , Adulto , Criança , Ensaios Clínicos como Assunto , Cromolina Sódica/administração & dosagem , Método Duplo-Cego , Humanos , Soluções Oftálmicas , Distribuição Aleatória
2.
Med Trop (Mars) ; 41(5): 511-4, 1981.
Artigo em Francês | MEDLINE | ID: mdl-7321842

RESUMO

We must consider: -- Superficial ocular myiasis affecting the lacrymal cul-de-sac and ducts and caused by oestridae larvae growing on conjunctiva or lacrymal ducts. -- Deep ocular myiasis affecting either the eyelids or the ocular globe and due to larvae pertaining to several families of flies and requiring an anaerobic phase in their development. This type of myiasis must be separated in two groups according to their localization in the camera anterior or in the camera posterior. Sometimes larvae are very, numerous and demonstrate a high potential of spreading and a phagedena. Surgical treatments are indicated.


Assuntos
Oftalmopatias/parasitologia , Miíase/patologia , Túnica Conjuntiva/parasitologia , Humanos , Aparelho Lacrimal/parasitologia , Miíase/etiologia , Miíase/cirurgia
4.
J Biomed Mater Res ; 48(6): 807-13, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-10556844

RESUMO

To investigate the effects of focal implantation of expanded polytetrafluoroethylene (e-PTFE) episcleral implants (i.e., explants or exoplants) on surrounding ocular tissues, an experimental and histopathological study was performed. Twenty-seven Fauve de Bourgogne rabbits eyes were implanted for a period of 3-11 months with oval-shaped e-PTFE episcleral implants. A newly formed capsule constantly encased the implants. Affected by the only two severe complications observed, 2 eyes had an endocapsular acute inflammation and could not be included in the study. Finally, 25 eyes were studied histopathologically. Neither intrusion nor extrusion of episcleral implants was observed. Other changes were related to implant characteristics. The inner surface of the capsule was often covered with numerous giant cells attesting to a foreign-body granuloma developed against the irregular outline of the episcleral implants. The porosity of the material was closely related to its surface irregularity, and also allowed its colonization by a fibrovascular and inflammatory tissue mainly in its peripheral layers. Under episcleral implants, sclera was both thinned and invaginated. Expanded PTFE hydrophobia was the other factor that might have suscitated granuloma. These microscopic changes are in contrast with an overall good apparent experimental tolerance to the material. However, additional studies on the long term behavior of this material would be helpful.


Assuntos
Materiais Biocompatíveis/toxicidade , Implantes Experimentais , Politetrafluoretileno/toxicidade , Esclera/patologia , Animais , Conjuntivite/induzido quimicamente , Conjuntivite/patologia , Olho/patologia , Granuloma/induzido quimicamente , Granuloma/patologia , Hidrogéis , Hiperemia/induzido quimicamente , Hiperemia/patologia , Teste de Materiais , Porosidade , Coelhos , Silicones
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