Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

HIV-Tat Exacerbates the Actions of Atazanavir, Efavirenz, and Ritonavir on Cardiac Ryanodine Receptor (RyR2).

Alomar, Fadhel A; Tian, Chengju; Bidasee, Sean R; Venn, Zachary L; Schroder, Evan; Palermo, Nicholas Y; AlShabeeb, Mohammad; Edagwa, Benson J; Payne, Jason J; Bidasee, Keshore R.

Int J Mol Sci ; 24(1)2022 Dec 23.

Artigo em Inglês | MEDLINE | ID: mdl-36613717

2.

A year-long extended release nanoformulated cabotegravir prodrug.

Kulkarni, Tanmay A; Bade, Aditya N; Sillman, Brady; Shetty, Bhagya Laxmi Dyavar; Wojtkiewicz, Melinda S; Gautam, Nagsen; Hilaire, James R; Sravanam, Sruthi; Szlachetka, Adam; Lamberty, Benjamin G; Morsey, Brenda M; Fox, Howard S; Alnouti, Yazen; McMillan, JoEllyn M; Mosley, R Lee; Meza, Jane; Domanico, Paul L; Yue, Tai-Yuen; Moore, Gary; Edagwa, Benson J; Gendelman, Howard E.

Nat Mater ; 19(8): 910-920, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32341511

3.

A long-acting 3TC ProTide nanoformulation suppresses HBV replication in humanized mice.

Wang, Weimin; Smith, Nathan; Makarov, Edward; Sun, Yimin; Gebhart, Catherine L; Ganesan, Murali; Osna, Natalia A; Gendelman, Howard E; Edagwa, Benson J; Poluektova, Larisa Y.

Nanomedicine ; 28: 102185, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32217146

4.

Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes.

Edagwa, Benson J; Guo, Dongwei; Puligujja, Pavan; Chen, Han; McMillan, JoEllyn; Liu, Xinming; Gendelman, Howard E; Narayanasamy, Prabagaran.

FASEB J ; 28(12): 5071-82, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25122556

5.

Broad-spectrum antivirals.

Edagwa, Benson J; Gendelman, Howard E.

Nat Mater ; 17(2): 114-116, 2018 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-31745273

6.

Antimicrobials: Broad-spectrum antivirals.

Edagwa, Benson J; Gendelman, Howard E.

Nat Mater ; 17(2): 114-116, 2018 01 23.

Artigo em Inglês | MEDLINE | ID: mdl-29358769

7.

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections.

Puligujja, Pavan; McMillan, Joellyn; Kendrick, Lindsey; Li, Tianyuzi; Balkundi, Shantanu; Smith, Nathan; Veerubhotla, Ram S; Edagwa, Benson J; Kabanov, Alexander V; Bronich, Tatiana; Gendelman, Howard E; Liu, Xin-Ming.

Nanomedicine ; 9(8): 1263-73, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23680933

8.

Chronic Hepatitis B Infection: New Approaches towards Cure.

Ogunnaike, Mojisola; Das, Srijanee; Raut, Samiksha S; Sultana, Ashrafi; Nayan, Mohammad Ullah; Ganesan, Murali; Edagwa, Benson J; Osna, Natalia A; Poluektova, Larisa Y.

Biomolecules ; 13(8)2023 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-37627273

9.

N-Acetyl-5-chloro-3-nitro-l-tyrosine ethyl ester.

Mutahi, Teresa T; Edagwa, Benson J; Fronczek, Frank R; Uppu, Rao M.

Acta Crystallogr Sect E Struct Rep Online ; 68(Pt 9): o2810-1, 2012 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-22969682

10.

An ultralong-acting tenofovir ProTide nanoformulation achieves monthslong HBV suppression.

Das, Srijanee; Wang, Weimin; Ganesan, Murali; Fonseca-Lanza, Franchesca; Cobb, Denise A; Bybee, Grace; Sun, Yimin; Guo, Lili; Hanson, Brandon; Cohen, Samuel M; Gendelman, Howard E; Osna, Natalia A; Edagwa, Benson J; Poluektova, Larisa Y.

Sci Adv ; 8(51): eade9582, 2022 Dec 23.

Artigo em Inglês | MEDLINE | ID: mdl-36563152

11.

Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment.

Bade, Aditya N; McMillan, JoEllyn M; Liu, Yutong; Edagwa, Benson J; Gendelman, Howard E.

Mol Neurobiol ; 58(11): 5703-5721, 2021 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-34390469

12.

Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir.

Gautam, Nagsen; McMillan, JoEllyn M; Kumar, Devendra; Bade, Aditya N; Pan, Qiaoyu; Kulkarni, Tanmay A; Li, Wenkuan; Sillman, Brady; Smith, Nathan A; Shetty, Bhagya L Dyavar; Szlachetka, Adam; Edagwa, Benson J; Gendelman, Howard E; Alnouti, Yazen.

Nat Commun ; 12(1): 3453, 2021 06 08.

Artigo em Inglês | MEDLINE | ID: mdl-34103484

13.

Long-acting approaches for delivery of antiretroviral drugs for prevention and treatment of HIV: a review of recent research.

Cobb, Denise A; Smith, Nathan A; Edagwa, Benson J; McMillan, JoEllyn M.

Expert Opin Drug Deliv ; 17(9): 1227-1238, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32552187

14.

Peptides containing gamma,delta-dihydroxy-L-leucine.

Edagwa, Benson J; Taylor, Carol M.

J Org Chem ; 74(11): 4132-6, 2009 Jun 05.

Artigo em Inglês | MEDLINE | ID: mdl-19413277

15.

Total Synthesis of Alloviroidin.

Taylor, Carol M; Kutty, Samuel K; Edagwa, Benson J.

Org Lett ; 21(7): 2281-2284, 2019 04 05.

Artigo em Inglês | MEDLINE | ID: mdl-30859823

16.

Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation.

Ibrahim, Ibrahim M; Bade, Aditya N; Lin, Zhiyi; Soni, Dhruvkumar; Wojtkiewicz, Melinda; Dyavar Shetty, Bhagya Laxmi; Gautam, Nagsen; McMillan, JoEllyn M; Alnouti, Yazen; Edagwa, Benson J; Gendelman, Howard E.

Int J Nanomedicine ; 14: 6231-6247, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31496683

17.

Synthesis of a long acting nanoformulated emtricitabine ProTide.

Soni, Dhruvkumar; Bade, Aditya N; Gautam, Nagsen; Herskovitz, Jonathan; Ibrahim, Ibrahim M; Smith, Nathan; Wojtkiewicz, Melinda S; Dyavar Shetty, Bhagya Laxmi; Alnouti, Yazen; McMillan, JoEllyn; Gendelman, Howard E; Edagwa, Benson J.

Biomaterials ; 222: 119441, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31472458

18.

Creation of a long-acting rilpivirine prodrug nanoformulation.

Hilaire, James R; Bade, Aditya N; Sillman, Brady; Gautam, Nagsen; Herskovitz, Jonathan; Dyavar Shetty, Bhagya Laxmi; Wojtkiewicz, Melinda S; Szlachetka, Adam; Lamberty, Benjamin G; Sravanam, Sruthi; Fox, Howard S; Alnouti, Yazen; Dash, Prasanta K; McMillan, JoEllyn M; Edagwa, Benson J; Gendelman, Howard E.

J Control Release ; 311-312: 201-211, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31491432

19.

Bioimaging predictors of rilpivirine biodistribution and antiretroviral activities.

Ottemann, Brendan M; Helmink, Austin J; Zhang, Wenting; Mukadam, Insiya; Woldstad, Christopher; Hilaire, James R; Liu, Yutong; McMillan, JoEllyn M; Edagwa, Benson J; Mosley, R Lee; Garrison, Jered C; Kevadiya, Bhavesh D; Gendelman, Howard E.

Biomaterials ; 185: 174-193, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30245386

20.

Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution.

Kevadiya, Bhavesh D; Woldstad, Christopher; Ottemann, Brendan M; Dash, Prasanta; Sajja, Balasrinivasa R; Lamberty, Benjamin; Morsey, Brenda; Kocher, Ted; Dutta, Rinku; Bade, Aditya N; Liu, Yutong; Callen, Shannon E; Fox, Howard S; Byrareddy, Siddappa N; McMillan, JoEllyn M; Bronich, Tatiana K; Edagwa, Benson J; Boska, Michael D; Gendelman, Howard E.

Theranostics ; 8(1): 256-276, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29290806

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