Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 41
Filtrar
Mais filtros

País/Região como assunto
Tipo de documento
Intervalo de ano de publicação
1.
Artigo em Inglês | MEDLINE | ID: mdl-38710818

RESUMO

PURPOSE: Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal musculature with no known etiology or cure. The present study evaluated the sociodemographic and clinical features of patients diagnosed with LD. MATERIALS AND METHODS: All patients diagnosed with LD at our University Hospital's Ear, Nose, and Throat Department between January 2017 and July 2023 were retrospectively analyzed. The study included 43 patients. RESULTS: Out of the 43 patients, 19 (44%) were male. At the time of diagnosis, the mean age of the patients was 35.1 years (ranging from 17 to 65 years). The mean elapsed time between the first symptom onset and the first diagnosis was 49.2 months (min. 4 months, max. 240 months). Of the participants, 94% had adductor-type LD. None of the patients had a family history of LD. Of the patients, 9 (20%) experienced a life-altering event or trauma just before the onset of symptoms. All patients who consumed alcohol reported symptom relief with alcohol intake. A total of 67.6% of patients stated that their symptoms were triggered by stress. All of our patients received at least one Botulinum toxin injection, with an average of 2.75 dosages per patient. CONCLUSION: The gender distribution was approximately equitable between males and females. There was a tendency for men to receive a diagnosis earlier than women following the manifestation of symptoms. A significant number of patients associate the emergence of their symptoms with a stressful event or traumatic experience. This study represents the initial investigation into the sociodemographic characteristics of patients within the Turkish population.

2.
Dysphagia ; 37(4): 800-811, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-34173063

RESUMO

This study investigated the effect of the structured Neurodevelopmental Therapy Method-Bobath (NDT-B) approach on the feeding and swallowing activity of patients with cerebral palsy (CP) and feeding difficulties. In addition to feeding and oral motor intervention strategies (OMIS), and nutrition-related caregiver training (NRCT), and the NDT-B, which was structured to increase trunk and postural control, was added to the therapy program. Forty patients with CP, with a mean age of 3.25 ± 0.927 years, were classified using the Gross Motor Function Classification System, Eating and Drinking Ability Classification System, and Mini-Manual Ability Classification System. The patients were randomly assigned into two groups as OMIS + NRCT (n = 20) and OMIS + NRCT + NDT-B (n = 20). The program was applied for 6 weeks, 2 days/week, for 45 min. The patients were evaluated using the Trunk Impairment Scale, Schedule for Oral Motor Assessment, and the Pediatric Quality of Life Inventory before and after 6 weeks. The trunk control of the OMIS + NRCT + NDT-B group was superior to the other group (P = 0.026). Although there was an improvement in the groups according to the subcategories of SOMA, the OMIS + NRCT + NDT-B group was superior in the trainer cup and puree subcategories of SOMA (P = 0.05). A significant correlation was observed between trunk control and oral motor functions in children with CP, and the eating function of children in the OMIS + NRCT + NDT-B group further improved. NDT-B-based neck and trunk stabilization exercises should be added to the treatment programs.Trial Registration NCT04403113.


Assuntos
Paralisia Cerebral , Paralisia Cerebral/complicações , Criança , Pré-Escolar , Deglutição , Terapia por Exercício , Humanos , Equilíbrio Postural , Qualidade de Vida
3.
Eur Arch Otorhinolaryngol ; 278(6): 1933-1943, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-33638681

RESUMO

OBJECTIVE: To study the management of laryngopharyngeal reflux (LPR) among the subspecialties of practicing otolaryngology-head and neck surgeons and their trainees. METHODS: A survey was sent to over 8000 otolaryngologists (OTOHNS) over 65 countries, utilizing membership lists of participating otolaryngological societies. The outcomes were answers to questions regarding LPR knowledge and practice patterns, and included queries about its definition, prevalence, clinical presentation, diagnosis, and treatment. RESULTS: Of the 824 respondents, 658 practiced in one specific otolaryngologic subspecialty. The symptoms and findings thought to be the most related to LPR varied significantly between subspecialists. Extra-laryngeal findings were considered less by laryngologists while more experienced OTOHNS did not often consider digestive complaints. Compared with colleagues, otologists, rhinologists and laryngologists were less aware of the involvement of LPR in otological, rhinological and laryngological disorders, respectively. Irrespective of subspecialty, OTOHNS consider symptoms and signs and a positive response to empirical therapeutic trial to establish a LPR diagnosis. Awareness regarding the usefulness of impedance pH-studies is low in all groups. The therapeutic approach significantly varies between groups, although all were in agreement for the treatment duration. The management of non-responder patients demonstrated significant differences among laryngologists who performed additional examinations. The majority of participants (37.1%) admitted to being less than knowledgeable about LPR management. CONCLUSIONS: LPR knowledge and management vary significantly across otolaryngology subspecialties. International guidelines on LPR management appear necessary to improve knowledge and management of LPR across all subspecialties of otolaryngology.


Assuntos
Refluxo Laringofaríngeo , Otolaringologia , Impedância Elétrica , Humanos , Refluxo Laringofaríngeo/diagnóstico , Refluxo Laringofaríngeo/terapia , Otorrinolaringologistas , Inquéritos e Questionários
4.
Turk J Med Sci ; 51(2): 819-825, 2021 04 30.
Artigo em Inglês | MEDLINE | ID: mdl-33350297

RESUMO

Background/aim: This study aimed to assess the inflammatory adverse reactions of vocal fold injection laryngoplasty with hyaluronic acid. Materials and methods: This study was a retrospective chart review of patients who underwent vocal fold injection augmentation with HA injection from January 2005 to September 2016 in nine different institutions. Demographic data, indication for injection, injection techniques, types of injection material, settings of procedure, and complications were reviewed. The types of complication, onset time, and management of complications were also noted. Results: In all, 467 patients were identified. The majority of patients had been injected under general anesthesia (n = 382, 84.7%). For injection material, two different types of hyaluronic acid were used: hyaluronic acid alone or hyaluronic acid with dextranomer. Complications occurred in nine patients (1.9%). The majority of complications were inflammatory reactions (n = 7, 1.47%). Main symptoms were dysphonia and/or dyspnea with an onset of 0 h to 3 weeks after the hyaluronic acid injection. Three patients were hospitalized, one of which was also intubated and observed in the intensive care unit for 24 h. Systemic steroids and antibiotics were the main medical treatment in the majority of cases. There was no statistical difference in complication rates between patients who received hyaluronic acid and those who received hyaluronic acid with dextranomer (P = 0.220). Conclusion: Hyaluronic acid can be considered as a safe substance for the injection of vocal folds with a low risk of inflammatory reaction.


Assuntos
Adjuvantes Imunológicos/administração & dosagem , Ácido Hialurônico/administração & dosagem , Laringoplastia , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Paralisia das Pregas Vocais/prevenção & controle , Prega Vocal/cirurgia , Adjuvantes Imunológicos/efeitos adversos , Adjuvantes Imunológicos/uso terapêutico , Adulto , Idoso , Feminino , Humanos , Ácido Hialurônico/efeitos adversos , Ácido Hialurônico/uso terapêutico , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Prega Vocal/lesões , Adulto Jovem
5.
Eur Arch Otorhinolaryngol ; 277(7): 2061-2069, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32180014

RESUMO

PURPOSE: The increasing availability of Internet as a health-care source causes both positive and negative effects on public health. Though reaching to information about diseases is faster and easier, the contents are not always correct and might be misleading. In our study, we aim to investigate the quality of YouTube™ videos on larynx cancer. METHODS: A YouTube™ search by using terms "throat cancer" and "larynx cancer" was done and, after eliminating the irrelevant videos, the first 200 videos were evaluated by three authors on quality, content and usefulness by using a pre-developed questionnaire. Videos were categorized according to the type and uploader separately to two (testimonial and educational) and five groups (health care, university, individual users, television channel/news and undetermined), respectively. RESULTS: Videos that are uploaded by university-affiliated accounts have significantly better audiovisual quality score and have significantly higher accuracy and usefulness score results. Furthermore, the accuracy and usefulness scores of the educational group were found to be statistically higher than those of the testimonial group. CONCLUSIONS: Videos uploaded by universities and videos that are created for educational purposes are superior to other sources in terms of quality, accuracy and content. Patient information videos discussing common health problems should be prepared and disseminated only by universities or health-care institutions.


Assuntos
Neoplasias Laríngeas , Mídias Sociais , Humanos , Gravação em Vídeo
6.
Eur Arch Otorhinolaryngol ; 276(12): 3389-3404, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31515662

RESUMO

OBJECTIVE: To develop clinical tools assessing the refluxogenic potential of foods and beverages (F&B) consumed by patients with laryngopharyngeal reflux (LPR). METHODS: European experts of the LPR Study group of the Young-Otolaryngologists of the International Federation of Oto-rhino-laryngological societies were invited to identify the components of Western European F&B that would be associated with the development of LPR. Based on the list generated by experts, four authors conducted a systematic review to identify the F&B involved in the development of esophageal sphincter and motility dysfunctions, both mechanisms involved in the development of gastroesophageal reflux disease and LPR. Regarding the F&B components and the characteristics identified as important in the development of reflux, experts developed three rational scores for the assessment of the refluxogenic potential of F&B, a dish, or the overall diet of the patient. RESULTS: Twenty-six European experts participated to the study and identified the following components of F&B as important in the development of LPR: pH; lipid, carbohydrate, protein composition; fiber composition of vegetables; alcohol degree; caffeine/theine composition; and high osmolality of beverage. A total of 72 relevant studies have contributed to identifying the Western European F&B that are highly susceptible to be involved in the development of reflux. The F&B characteristics were considered for developing a Refluxogenic Diet Score (REDS), allowing a categorization of F&B into five categories ranging from 1 (low refluxogenic F&B) to 5 (high refluxogenic F&B). From REDS, experts developed the Refluxogenic Score of a Dish (RESDI) and the Global Refluxogenic Diet Score (GRES), which allow the assessment of the refluxogenic potential of dish and the overall diet of the LPR patient, respectively. CONCLUSION: REDS, RESDI and GRES are proposed as objective scores for assessing the refluxogenic potential of F&B composing a dish or the overall diet of LPR patients. Future studies are needed to study the correlation between these scores and the development of LPR according to impedance-pH study.


Assuntos
Bebidas , Dieta , Alimentos , Refluxo Laringofaríngeo/dietoterapia , Otorrinolaringologistas , Adulto , Impedância Elétrica , Esofagite Péptica , Feminino , Humanos , Concentração de Íons de Hidrogênio , Refluxo Laringofaríngeo/diagnóstico , Refluxo Laringofaríngeo/metabolismo , Masculino , Pessoa de Meia-Idade , Otolaringologia , Índice de Gravidade de Doença
7.
J Craniofac Surg ; 28(3): e254-e255, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28468210

RESUMO

Meningiomas are common intracranial neoplasms but extracranial meningioma of the paranasal sinus is extremely rare. The recommended treatment of these meningothelial tumors is complete surgical excision. The authors report a 79-year-old woman presenting with facial pain and nasal obstruction for several months. Endoscopic nasopharyngeal examination showed a right nasal mass that arose from the nasopharynx and reached around the middle meatus. Gadolinium-enhanced magnetic resonance imaging showed a well-circumscribed nasopharyngeal mass, which originates from the right rosenmuller fossa and extends to the right nasal cavity. A biopsy was made with nasal endoscopy under local anesthesia for definitive diagnosis. Histopathologic examination was reported as benign meningothelial meningioma.In conclusion, physicians should keep in mind uncommon tumors in the nasal cavity and paranasal sinuses. Surgical resection is the primary treatment choice; however, close follow-up could be an option in patients with comorbidities.


Assuntos
Neoplasias Meníngeas/diagnóstico , Meningioma/diagnóstico , Neoplasias Nasofaríngeas/diagnóstico , Neoplasias dos Seios Paranasais/diagnóstico , Idoso , Feminino , Humanos , Neoplasias Meníngeas/patologia , Meningioma/patologia , Cavidade Nasal/patologia , Neoplasias Nasofaríngeas/patologia , Invasividade Neoplásica , Neoplasias dos Seios Paranasais/patologia , Seios Paranasais/patologia
8.
J Craniofac Surg ; 27(4): 1025-7, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27244209

RESUMO

PURPOSE: To assess the effectiveness and usefulness of transnasal prelacrimal recess approach (TPRA) in patients with recurrent antrochoanal polyps. METHODS: Twelve patients with antrochoanal polyp recurrence underwent surgery with a transnasal endoscopic prelacrimal recess approach. Success for visualization of the origin of the polyps, surgical complications, and recurrence was evaluated. RESULTS: Transnasal prelacrimal recess approach was successful in 83% of the patients (10/12); polyps that originated from a posterior location (2 patients) were excised using the middle meatal approach. Nasolacrimal duct injury occurred in 2 patients but neither had epiphora postoperatively. Three patients (3/12; 25%) had synechia formation between the lateral nasal wall and septum just superior to the inferior turbinate. One of the 3 patients (1/12; 8.3%) with synechia was symptomatic and required surgical treatment under local anesthesia. During a mean follow-up period of 14.2 months (range, 8-21 months) no recurrence had developed. CONCLUSION: In experienced hands, TPRA is a novel, reliable, and useful method for the treatment of recurrent antrochoanal polyps. It ensures good exploration of the maxillary antrum and easy access to the polyp origin on the maxillary wall without the need of additional approaches.


Assuntos
Seio Maxilar/cirurgia , Pólipos Nasais/cirurgia , Ducto Nasolacrimal/cirurgia , Cirurgia Endoscópica por Orifício Natural/métodos , Adolescente , Adulto , Feminino , Humanos , Masculino , Pólipos Nasais/diagnóstico , Nariz , Período Pós-Operatório , Recidiva , Tomografia Computadorizada por Raios X , Adulto Jovem
9.
Laryngoscope ; 134(4): 1802-1806, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37747121

RESUMO

OBJECTIVES: The primary objective was to assess the perspectives of recent laryngology fellowship graduates on office-based procedure training, with a secondary objective to compare this with previous research on perspectives of fellowship directors. METHODS: Recent laryngology fellowship graduates were surveyed via an online survey platform regarding post-fellowship practice and various aspects of office-based procedure training, including perceived competence, mentorship, and barriers. RESULTS: There were 51 respondents. Seventy-six percent of respondents felt they "definitely" received adequate office procedure training. Number of procedures as primary surgeon was significantly associated with perception of adequate training (OR 1.54, 95% CI: 1.08-2.19, p = 0.018) and high post-fellowship office procedure volume (OR 1.56, 95% CI: 1.02-2.39, p = 0.040). Fellows reported a lower percentage of procedures as primary surgeons compared with program directors (46.8% vs. 61.9%, p = 0.028). Fellows and directors agreed that informal debriefs were more commonly employed than more structured training elements such as checklists and simulators. Of nine office procedures, laryngeal electromyography, KTP laser, and transnasal esophagoscopy had the greatest decreases in practice after training. CONCLUSION: Although most recent laryngology fellowship graduates endorse adequate office-based procedure training, a range of individual experiences exists, and office procedure volume, both overall and across individual procedures, may decrease after fellowship. Fellows performing office procedures as primary surgeons may be linked to perceived quality of training and post-fellowship volume. LEVEL OF EVIDENCE: NA Laryngoscope, 134:1802-1806, 2024.


Assuntos
Educação de Pós-Graduação em Medicina , Otolaringologia , Humanos , Educação de Pós-Graduação em Medicina/métodos , Bolsas de Estudo , Inquéritos e Questionários , Currículo , Otolaringologia/educação
10.
Laryngoscope ; 134(3): 1118-1126, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37497865

RESUMO

OBJECTIVE: High-resolution esophageal manometry (HRM) is the gold standard for the diagnosis of esophageal motility disorders. HRM is typically performed in the office with local anesthesia only, and many patients find it unpleasant and painful. The aim of this study was to examine the effects of the use of a virtual reality (VR) headset on pain and anxiety outcomes in patients with dysphagia undergoing HRM. METHODS: Patients with dysphagia were prospectively recruited and randomized to undergo HRM with and without VR distraction. Data collected included the State-Trait Anxiety Inventory-6 (STAI-6), the Short-Form McGill Pain Questionnaire, heart rate, and galvanic skin response (GSR) tracings. RESULTS: Forty subjects completed the study, including 20 subjects in the intervention arm and 20 in the control arm. There was evidence of a significant positive effect of VR on calmness (p = 0.0095) STAI-6 rating, as well as on physiologic measures of pain with significantly decreased GSR rise time (p = 0.0137) and average rate of change of conductance change (p = 0.0035). CONCLUSION: The use of VR during HRM catheter insertion increased calmness compared to control. Change of skin conductance was also reduced in the VR group, suggesting decreased physiologic pain. This study supports the consideration of the use of VR as a distraction tool to improve patient comfort during HRM. LEVEL OF EVIDENCE: 2 Laryngoscope, 134:1118-1126, 2024.


Assuntos
Transtornos de Deglutição , Realidade Virtual , Humanos , Manejo da Dor , Transtornos de Deglutição/diagnóstico , Dor/diagnóstico , Dor/etiologia , Manometria , Ansiedade
11.
J Voice ; 37(5): 801.e9-801.e15, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34175169

RESUMO

PURPOSE: Awareness of variations in laryngeal anatomy among different age and gender groups is crucial during laryngeal framework surgery. The aim of this study is to demonstrate the relationship between gender and laryngeal radiologic morphometrics among different age groups and the applicability of important anatomical landmarks of laryngeal surgery. METHODS: Laryngeal images of 180 adult patients older than 18 years of age were obtained by computed tomography and assessed. A total of 11 measurements of important laryngeal landmarks were taken from the patients' computed tomography images. Results were subgrouped according to gender and age, and these groups were compared for each measurement. RESULTS: The majority of laryngeal measurements obtained in the study were higher in males than females, with the exception of the interlaminar angle. The mean interlaminar angle value was 88.27°± 14.99 for males and 103.04°± 14.81 for females (P <0.005). The distance from the anterior commissure to the inferior border of the thyroid cartilage was 10.46 ± 2.5 mm for males and 7.72 ± 1.9 mm for females. The anterior commissure locates slightly higher than the midpoint of the distance from the thyroid notch to the thyroid inferior border. The shortest distance between the muscular process of the arytenoid cartilage and the thyroid cartilage was found to be 9.60 ± 3.47 mm for males and 7.72 ± 2.33 mm for females (P <0.001). CONCLUSION: Observation of obvious diversities in the size and distance of the important laryngeal structures between the gender groups is an important factor to be considered for successful laryngeal framework surgery. Also, using the midpoint of the thyroid cartilage as a landmark for anterior commissure is a practical method during surgery, especially for thyroplasty.


Assuntos
Laringoplastia , Laringe , Masculino , Adulto , Feminino , Humanos , Laringe/diagnóstico por imagem , Laringe/cirurgia , Laringe/anatomia & histologia , Cartilagem Tireóidea/diagnóstico por imagem , Cartilagem Tireóidea/cirurgia , Cartilagem Aritenoide/anatomia & histologia , Tomografia Computadorizada por Raios X
12.
Laryngoscope ; 133(9): 2333-2339, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-36594519

RESUMO

OBJECTIVE: To assess the duration of clinical response after in-office vocal fold steroid injection (VFSI) for vocal fold (VF) scar. METHODS: Demographic and clinical data for in-office VFSI occurring from 2017 to 2020 were collected. Two Speech-Language Pathologists (SLPs) used perceptual evaluation of voice and functional scales to evaluate blinded voice and laryngovideostroboscopy (LVS) samples collected pre- and post-injection across multiple timepoints. RESULTS: Blinded SLP ratings were used for 30 individual VFs undergoing initial injection in 18 patients. Persistent improvement in voice past 6 months was seen in 57% of patients after VFSI. Multiple measures of voice and amplitude, percent vibrating tissue, and closed phase predominance significantly improved at various follow-up timepoints on average. CONCLUSION: Accounting for patient heterogeneity and disease progression, in-office VFSI for VF scar is associated with sustained improvement in a subset of patients. Approximately half of patients can expect to experience a lasting improvement in voice. Future studies of larger scale are required to identify patient factors associated with long-term benefit. LEVEL OF EVIDENCE: 4 Laryngoscope, 133:2333-2339, 2023.


Assuntos
Cicatriz , Complicações Pós-Operatórias , Esteroides , Prega Vocal , Distúrbios da Voz , Humanos , Cicatriz/tratamento farmacológico , Cicatriz/etiologia , Esteroides/farmacologia , Esteroides/uso terapêutico , Resultado do Tratamento , Prega Vocal/efeitos dos fármacos , Prega Vocal/patologia , Qualidade da Voz/efeitos dos fármacos , Patologia da Fala e Linguagem , Fatores de Tempo , Complicações Pós-Operatórias/tratamento farmacológico , Masculino , Feminino , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Distúrbios da Voz/tratamento farmacológico , Distúrbios da Voz/etiologia
13.
J Voice ; 2023 Jan 20.
Artigo em Inglês | MEDLINE | ID: mdl-36682999

RESUMO

OBJECTIVES: To develop a reproducible experimental animal model for sulcus vergeture in rabbits. STUDY DESIGN: Experimental animal study. MATERIAL METHOD: We evaluated three methods of inducing sulcus in twelve New Zealand white rabbits to produce a sulcus model. Experimental groups comprised: group 1 (n = 4) underwent submucosal injury following endolaryngeal epithelial incision; group 2 (n = 4) received submucosal injury via thyrotomy; group 3 (n = 4) received submucosal injury via thyrotomy, followed with horizontal mucosal lateralization suture. Right vocal folds of the rabbits underwent surgery to produce sulcus vocalis and left vocal folds were used for the comparison. In the sixth week after the procedure, the rabbits were sacrificed and the larynxes were harvested and analyzed histopathologically. RESULTS: No animals in group 1 or 2 developed sulcus vocalis. Sulcus formation was observed in all rabbits in group 3, under endoscopic examination and microscopic sulcus formation was demonstrated for the first, second, and third rabbits. An epithelial depression area was seen at the glandular ductal opening zone for the fourth rabbit, but it could also be accepted as a sulcus formation. CONCLUSION: We successfully developed a reproducible survival model for sulcus using a submucosal injury via thyrotomy, followed with a horizontal mucosal lateralization suture. This model provides the groundwork for future research into the applicability of new approaches for sulcus management.

14.
Auris Nasus Larynx ; 50(3): 410-414, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36064766

RESUMO

OBJECTIVES: The thyroid imaging reporting and data system (TI-RADS) and 2015 American Thyroid Association (ATA) guidelines are two well-known risk stratification systems for classifying thyroid nodules based on cancer risk. This study aims to evaluate the diagnostic efficacy of these two systems in predicting malignancy in patients undergoing thyroid surgery. METHODS: We studied data on 120 individuals who were scheduled to undergo surgery for benign or malignant nodular diseases of the thyroid gland between October 2017 and October 2019. The TI-RADS category and ultrasound pattern based on ATA guidelines were assigned to dominant thyroid nodule categories by two experienced radiologists blinded to patients' previous thyroid ultrasonography and fine-needle aspiration biopsy results. A pathologist with experience in thyroid diseases blinded to patients' sonographic and clinical data reviewed the thyroidectomy specimens. RESULTS: A total of 120 patients, 88 women and 32 men, were included in our study. Final histopathological results were as follows: 50% (n=60) papillary thyroid carcinoma, 36.6% (n=44) benign nodular thyroid diseases, 4.1% (n=5) follicular adenoma, 2.5% (n=3) hurtle cell adenoma, 1.7% (n=2) follicular thyroid carcinoma, 1.7% (n=2) medullary thyroid carcinoma, 1.7% (n=2) hurtle cell carcinoma, and 1.7% (n=2) follicular tumor of uncertain malignancy potential. The sensitivity, specificity, positive predictive value, and negative predictive value for TI-RADS were 80%, 56%, 72%, and 67%, respectively, and that for ATA were 80%, 64%, 76%, and 69%, respectively. CONCLUSION: The TI-RADS and ATA showed similar rates of sensitivity, specificity, NPV, and PPV. Our observed risk of malignancy was higher than expected for the ACR TI-RADS 3-5 categories and the very low, low, and intermediate suspicion risk strata in the ATA guidelines. We found no difference between observed and expected malignancy risk for the ACR TI-RADS 2's and ATA's high suspicion categories.


Assuntos
Carcinoma Neuroendócrino , Neoplasias da Glândula Tireoide , Nódulo da Glândula Tireoide , Masculino , Humanos , Feminino , Estados Unidos , Nódulo da Glândula Tireoide/diagnóstico por imagem , Nódulo da Glândula Tireoide/cirurgia , Sistemas de Dados , Neoplasias da Glândula Tireoide/diagnóstico por imagem , Neoplasias da Glândula Tireoide/patologia , Ultrassonografia/métodos , Estudos Retrospectivos , Medição de Risco/métodos
15.
Ear Nose Throat J ; : 1455613231210976, 2023 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-38050868

RESUMO

Objectives: Dysphagia is common in idiopathic Parkinson's disease (IPD) and is associated with impairments in both swallowing safety and swallowing efficiency. The goals of this study were to define post-swallow residue patterns in people with IPD and describe pathophysiological endoscopic findings affecting residue accumulation. Methods: This was a prospective single-blinded cross-sectional cohort study of patients with the diagnosis of IPD recruited from a Movement Disorder Clinic. Clinical variables included patient age, cognitive function, and measures of disease severity, and laryngoscopic examinations with a flexible endoscopic evaluation of swallowing (FEES) were completed for each patient. Visual Analysis of Swallowing Efficiency and Safety (VASES) was used to analyze FEES. Post-swallow residue outcomes and non-residue endoscopic outcomes including the Bowing index, Penetration Aspiration Scale (PAS) score, premature leakage, and build-up phenomenon were evaluated. Multiple regression models were used to evaluate factors affecting the residue at different anatomic levels. Results: Overall 53 patients completed the study. The multiple regression analyses showed a relation between (1) the presence of residue at the level of oropharynx and epiglottis with premature leakage, (2) the presence of residue at the level of the laryngeal vestibule and vocal folds with build-up phenomenon, and (3) the presence of residue at the level of the hypopharynx, laryngeal vestibule, and subglottis with airway invasion. Conclusion: Residue pattern during FEES is associated with specific swallow dysfunctions in IPD. Using residue localization and quantification may be a helpful tool in assessing the impact of targeted swallowing interventions in patients with IPD and dysphagia.

16.
Braz J Otorhinolaryngol ; 88 Suppl 4: S1-S8, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34144901

RESUMO

INTRODUCTION: Gelsolin protein has important cellular functions, including cell motility and apoptosis. Altered gelsolin expression has been reported in several types of neoplasms, but clinicopathological features of gelsolin are currently unclear in patients with laryngeal squamous cell carcinoma. OBJECTIVES: Our aim is to investigate the clinicopathological significance of gelsolin as a prognostic biomarker for laryngeal squamous cell carcinoma. METHODS: Tissue specimens from 168 patients with laryngeal squamous cell carcinoma were immunohistochemically assessed for the Gelsolin expression. Prognostic significance of Gelsolin and its interaction with clinical parameters was analysed. RESULTS: Gelsolin expression was confirmed in 70.2% of cases. Gelsolin expression is significantly associated with tumor stage, tumor grade, and locoregional recurrence. Kaplan-Meier survival curves revealed that Gelsolin expression inversely correlated with both disease-specific and overall survival. CONCLUSION: This research is the first to demonstrate that Gelsolin expression is associated with a poor prognosis in laryngeal squamous cell carcinoma. Gelsolin is a novel promising biomarker and attractive target for the treatment of laryngeal squamous cell carcinoma.


Assuntos
Carcinoma de Células Escamosas , Neoplasias de Cabeça e Pescoço , Neoplasias Laríngeas , Humanos , Gelsolina/análise , Gelsolina/metabolismo , Neoplasias Laríngeas/patologia , Carcinoma de Células Escamosas de Cabeça e Pescoço , Recidiva Local de Neoplasia , Carcinoma de Células Escamosas/patologia , Prognóstico , Biomarcadores Tumorais/análise
17.
Ear Nose Throat J ; 100(10_suppl): 1061S-1072S, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32579405

RESUMO

OBJECTIVES: The number of citations an article receives is an important indication of its impact. The main objectives of this investigation provide readers with a practical guide in evaluating head and neck oncology literature and determine the characteristics of trends in ORL. METHODS: This was a retrospective bibliometric analysis that did not involve human participant. The Thomson Reuters Web of Science was searched to determine the citations of all published HNO articles. Most cited 300 article analyzed and a total of 100 articles were included in our investigation under the topic search "Head AND NECK AND (cancer OR carcinoma OR oncology)." Articles include malignancies other than head and neck are excluded. The top 100 cited articles were selected and analyzed by 2 independent investigators. Country, Institution, First Author, Journal name, study design, cites per year information gathered and analyzed. RESULTS: The journal with the highest number of top 100 cited articles was New England Journal Of Medicine with 19 paper, followed by The Journal of Clinical Oncology(17) and Cancer Research (12). The top article on the list (Radiotherapy plus cetuximab for squamous cell carcinoma of the head and neck-NEJM) has 2243 citations. A statistically significant association was found between the journal impact factor and the number of top 100 cited articles (P < .05). The United States had the highest number of articles (63). John Hopkins is differed from other institutions with 15 contributing articles. CONCLUSION: Our analysis provides an insight into the citation frequency of top cited articles published in HNO to help recognize the quality of the works, discoveries and the trends steering the study of HNO. This is also a modern reading list for young HNO scientist.


Assuntos
Bibliometria , Neoplasias de Cabeça e Pescoço , Oncologia/estatística & dados numéricos , Humanos , Fator de Impacto de Revistas , Estudos Retrospectivos
18.
Laryngoscope ; 131(9): 2054-2058, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-33043999

RESUMO

OBJECTIVE: To assess the current practices and challenges of training office-based procedures to laryngology fellows in the United States. METHODS: An anonymous web-based survey study was distributed to laryngology fellowship program directors, as listed by the American Laryngological Association. The survey was a 19-item questionnaire with free-text, Likert scale, and multiple-choice answers. RESULTS: Twenty-two of 27 program directors (81.4%) replied to the survey. Many programs (8/16) have three or more laryngologists and do more than 10 procedures each week (10/16). Sixty-nine percent (11/16) of directors had not been trained for office procedures in their fellowship. The fellows are allowed to be primary surgeon on 68.75% and 75% of vocal fold augmentation and laser procedures, respectively. The expected competencies for these procedures on graduation are average-moderate and moderate. When program directors asked about the methods used for training, a minority of them use simulators (2/16), procedural checklists (2/16), or structured debriefing (2/16). The most commonly used methods were case-based troubleshooting (13/16) and unstructured debriefing (13/16). Patients being awake and patients' expectations are seen as the most important obstacles. Most of the directors thought office-based procedure training could be improved (14/16). The most common suggestions were using step-wise checklists, simulator-labs, and formal debriefings. CONCLUSION: This is the first study evaluating the training of office-based laryngeal procedures during laryngology fellowship. Given the increasing importance of these procedures in practice and the herein identified barriers and need for improvement, fellowships should investigate the use of systematic training tools to improve fellow competency with office-based procedures. Laryngoscope, 131:2054-2058, 2021.


Assuntos
Procedimentos Cirúrgicos Ambulatórios/educação , Educação de Pós-Graduação em Medicina/métodos , Educação/métodos , Otolaringologia/educação , Procedimentos Cirúrgicos Ambulatórios/estatística & dados numéricos , Lista de Checagem/estatística & dados numéricos , Competência Clínica/estatística & dados numéricos , Educação de Pós-Graduação em Medicina/tendências , Bolsas de Estudo/estatística & dados numéricos , Humanos , Terapia a Laser/métodos , Terapia a Laser/estatística & dados numéricos , Otolaringologia/organização & administração , Treinamento por Simulação/estatística & dados numéricos , Inquéritos e Questionários , Estados Unidos , Prega Vocal/cirurgia
19.
J Voice ; 35(1): 129-135, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31477349

RESUMO

INTRODUCTION: Thyroidectomy is one of the most commonly performed surgical procedures. Preoperative patient education and postoperative management of complications are vital to avoid postoperative medicolegal problems. OBJECTIVE: The aim of this study was to assess the attitudes of thyroid surgeons about voice and airway complications of the surgery and the approaches used to avoid or handle these complications. METHODS: A questionnaire based on surgeons' attitudes and behaviors on thyroidectomy was answered by 177 thyroid surgeons. Questions regarding demographic information, preoperative information methods, preoperative laryngeal examination, intraoperative nerve preservation techniques, and methods to avoid and handle postoperative complications were asked. Surgeons who completed the questionnaire were divided into three groups based on their annual volumes: less than 50 (low volume), 50-100 (middle volume), and more than 100 (high volume) for statistical analysis. The differences between the subgroups were compared using the chi-squared test. RESULTS: During the preoperative disclosure, nearly all surgeons (97.2%) gave information about possible hoarseness; however, this high rate fell to 79.7% for possible voice changes, and to the lowest level of 36.7% for ability to change the voice pitch. Only 53.7% of the surgeons discussed the possibility of postoperative tracheostomy requirement. The surgeons with high annual volumes were found to perform vocal fold examination prior to a second surgery significantly higher than other groups (P=0.015). In the postoperative period, 84.2% of physicians indicated that they perform a laryngoscopic examination only for patients with voice problems. There was no statistically important difference between subgroups. CONCLUSIONS: Our study is unique to provide information from the surgeons' perspective by evaluating preoperative patient information, and intraoperative and postoperative protective and curative methods. The training of residents and fellows who are expected to perform thyroidectomies can be revised to compromise all aspects of complications.


Assuntos
Cirurgiões , Glândula Tireoide , Atitude , Humanos , Complicações Pós-Operatórias/etiologia , Inquéritos e Questionários , Tireoidectomia/efeitos adversos , Turquia
20.
Nutr Clin Pract ; 36(4): 828-832, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34161626

RESUMO

Oropharyngeal dysphagia is one of the complications of endotracheal intubation. As expected, cases of dysphagia following coronavirus disease 2019 (COVID-19) reported to date have all been intubated. We here report a case of sarcopenic dysphagia following severe COVID-19 pneumonia in a nonintubated older adult. The patient was an 85-year-old male who was readmitted to the hospital with dysphagia and subsequent aspiration pneumonia in the first week after his discharge from the COVID-19 unit. On physical examination, the patient was sarcopenic and malnourished. Flexible endoscopic evaluation of swallowing (FEES) revealed aspiration into the airway. Enteral feeding was initiated and the infusion rate gradually increased to achieve the desired protein-energy targets. Control FEES 2 months after discharge showed recovery of swallowing function, with no apparent penetration or aspiration. Clinicians caring for patients with COVID-19 should be aware that dysphagia, which is associated with increased mortality in older adults, may occur even in the absence of intubation. We recommend that the evaluation of dysphagia be part of the clinical assessment in older COVID-19 patients with malnutrition or sarcopenia.


Assuntos
COVID-19 , Transtornos de Deglutição , Pneumonia Aspirativa , Sarcopenia , Idoso , Idoso de 80 Anos ou mais , Transtornos de Deglutição/etiologia , Humanos , Masculino , Pneumonia Aspirativa/etiologia , SARS-CoV-2 , Sarcopenia/complicações
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA