Detalhe da pesquisa
1.
Latent-Transforming Growth Factor ß-Binding Protein 1/Transforming Growth Factor ß1 Complex Drives Antitumoral Effects upon ERK5 Targeting in Melanoma.
Am J Pathol
; 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38705382
2.
ERK5 Interacts with Mitochondrial Glutaminase and Regulates Its Expression.
Int J Mol Sci
; 25(6)2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542254
3.
The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma.
Gut
; 64(9): 1454-65, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25183205
4.
MEK5 promotes lung adenocarcinoma.
Eur Respir J
; 53(2)2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442718
5.
Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue.
Stem Cells
; 31(6): 1075-85, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23401361
6.
Etiopathogenic role of ERK5 signaling in sarcoma: prognostic and therapeutic implications.
Exp Mol Med
; 55(6): 1247-1257, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37332046
7.
The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib.
Clin Transl Med
; 13(4): e1217, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37029785
8.
Inhibition of ERK5 Elicits Cellular Senescence in Melanoma via the Cyclin-Dependent Kinase Inhibitor p21.
Cancer Res
; 82(3): 447-457, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34799355
9.
ERK5 Is a Major Determinant of Chemical Sarcomagenesis: Implications in Human Pathology.
Cancers (Basel)
; 14(14)2022 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35884568
10.
Clinical, genetic and pharmacological data support targeting the MEK5/ERK5 module in lung cancer.
NPJ Precis Oncol
; 5(1): 78, 2021 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34404896
11.
The extracellular linker of pro-neuregulin-alpha2c is required for efficient sorting and juxtacrine function.
Mol Biol Cell
; 18(2): 380-93, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17108327
12.
Inhibition of the mitotic kinase PLK1 overcomes therapeutic resistance to BET inhibitors in triple negative breast cancer.
Cancer Lett
; 491: 50-59, 2020 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32735909
13.
Neuregulins and cancer.
Clin Cancer Res
; 14(11): 3237-41, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18519747
14.
Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R-MEK5-Erk5 Pathway.
Cancer Res
; 79(9): 2244-2256, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833419
15.
Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer.
J Exp Clin Cancer Res
; 38(1): 383, 2019 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31470872
16.
A Transcriptomic Immunologic Signature Predicts Favorable Outcome in Neoadjuvant Chemotherapy Treated Triple Negative Breast Tumors.
Front Immunol
; 10: 2802, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31921107
17.
The mitogen-activated protein kinase Erk5 mediates human mesangial cell activation.
Nephrol Dial Transplant
; 23(11): 3403-11, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18567890
18.
Erk5 nuclear location is independent on dual phosphorylation, and favours resistance to TRAIL-induced apoptosis.
Cell Signal
; 19(7): 1473-87, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17317102
19.
Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2.
Mol Cell Biol
; 22(1): 270-85, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11739740
20.
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.
Mol Biol Cell
; 13(6): 2031-44, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12058067