Detalhe da pesquisa
1.
Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults.
N Engl J Med
; 384(7): 610-618, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33406353
2.
Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J Biol Chem
; 297(3): 101039, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34343569
3.
Uncovering Causes of Childhood Death Using the Minimally Invasive Autopsy at the Community Level in an Urban Vulnerable Setting of Argentina: A Population-Based Study.
Clin Infect Dis
; 73(Suppl_5): S435-S441, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34910178
4.
Community Mortality Due to Respiratory Syncytial Virus in Argentina: Population-based Surveillance Study.
Clin Infect Dis
; 73(Suppl_3): S210-S217, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34472572
5.
Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus.
Biochemistry
; 58(26): 2883-2892, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31243994
6.
Intrinsic Disorder to Order Transitions in the Scaffold Phosphoprotein P from the Respiratory Syncytial Virus RNA Polymerase Complex.
Biochemistry
; 55(10): 1441-54, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26901160
7.
Fine modulation of the respiratory syncytial virus M2-1 protein quaternary structure by reversible zinc removal from its Cys(3)-His(1) motif.
Biochemistry
; 52(39): 6779-89, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23984912
8.
Nuclease Activity of the Junín Virus Nucleoprotein C-Terminal Domain.
Viruses
; 15(9)2023 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37766225
9.
Molten Globule Driven and Self-downmodulated Phase Separation of a Viral Factory Scaffold.
J Mol Biol
; 435(16): 168153, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37210029
10.
Modular unfolding and dissociation of the human respiratory syncytial virus phosphoprotein p and its interaction with the m(2-1) antiterminator: a singular tetramer-tetramer interface arrangement.
Biochemistry
; 51(41): 8100-10, 2012 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22978633
11.
The respiratory syncytial virus transcription antiterminator M(2-1) is a highly stable, zinc binding tetramer with strong pH-dependent dissociation and a monomeric unfolding intermediate.
Biochemistry
; 50(40): 8529-39, 2011 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21877705
12.
Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
FEBS J
; 288(1): 310-324, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32324953
13.
Prion soft amyloid core driven self-assembly of globular proteins into bioactive nanofibrils.
Nanoscale
; 11(26): 12680-12694, 2019 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31237592
14.
Identification and characterization of four PAX8 rare sequence variants (p.T225M, p.L233L, p.G336S and p.A439A) in patients with congenital hypothyroidism and dysgenetic thyroid glands.
Clin Endocrinol (Oxf)
; 68(5): 828-35, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17980011
15.
Mechanism of Tetramer Dissociation, Unfolding, and Oligomer Assembly of Pneumovirus M2-1 Transcription Antiterminators.
ACS Omega
; 3(11): 14732-14745, 2018 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30555987
16.
Cooperative RNA Recognition by a Viral Transcription Antiterminator.
J Mol Biol
; 430(6): 777-792, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29414675
17.
Structure and stability of the Human respiratory syncytial virus M2-1 RNA-binding core domain reveals a compact and cooperative folding unit.
Acta Crystallogr F Struct Biol Commun
; 74(Pt 1): 23-30, 2018 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29372904
18.
Author Correction: Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.
Nat Commun
; 14(1): 582, 2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36737445
19.
Plasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI).
Sci Rep
; 7(1): 5457, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710462
20.
Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep
; 7: 44709, 2017 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28338000