Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause.

Scognamiglio, Roberta; Cabezas-Wallscheid, Nina; Thier, Marc Christian; Altamura, Sandro; Reyes, Alejandro; Prendergast, Áine M; Baumgärtner, Daniel; Carnevalli, Larissa S; Atzberger, Ann; Haas, Simon; von Paleske, Lisa; Boroviak, Thorsten; Wörsdörfer, Philipp; Essers, Marieke A G; Kloz, Ulrich; Eisenman, Robert N; Edenhofer, Frank; Bertone, Paul; Huber, Wolfgang; van der Hoeven, Franciscus; Smith, Austin; Trumpp, Andreas.

Cell ; 164(4): 668-80, 2016 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-26871632

2.

Towards reliable quantification of cell state velocities.

Marot-Lassauzaie, Valérie; Bouman, Brigitte Joanne; Donaghy, Fearghal Declan; Demerdash, Yasmin; Essers, Marieke Alida Gertruda; Haghverdi, Laleh.

PLoS Comput Biol ; 18(9): e1010031, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36170235

3.

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

Walter, Dagmar; Lier, Amelie; Geiselhart, Anja; Thalheimer, Frederic B; Huntscha, Sina; Sobotta, Mirko C; Moehrle, Bettina; Brocks, David; Bayindir, Irem; Kaschutnig, Paul; Muedder, Katja; Klein, Corinna; Jauch, Anna; Schroeder, Timm; Geiger, Hartmut; Dick, Tobias P; Holland-Letz, Tim; Schmezer, Peter; Lane, Steven W; Rieger, Michael A; Essers, Marieke A G; Williams, David A; Trumpp, Andreas; Milsom, Michael D.

Nature ; 520(7548): 549-52, 2015 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-25707806

4.

IFNα-mediated remodeling of endothelial cells in the bone marrow niche.

Prendergast, Áine M; Kuck, Andrea; van Essen, Mieke; Haas, Simon; Blaszkiewicz, Sandra; Essers, Marieke A G.

Haematologica ; 102(3): 445-453, 2017 03.

Artigo em Inglês | MEDLINE | ID: mdl-27742772

5.

Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia.

Wang, Wenwen; Stiehl, Thomas; Raffel, Simon; Hoang, Van T; Hoffmann, Isabel; Poisa-Beiro, Laura; Saeed, Borhan R; Blume, Rachel; Manta, Linda; Eckstein, Volker; Bochtler, Tilmann; Wuchter, Patrick; Essers, Marieke; Jauch, Anna; Trumpp, Andreas; Marciniak-Czochra, Anna; Ho, Anthony D; Lutz, Christoph.

Haematologica ; 102(9): 1567-1577, 2017 09.

Artigo em Inglês | MEDLINE | ID: mdl-28550184

6.

Hyperinflammation in patients with chronic granulomatous disease leads to impairment of hematopoietic stem cell functions.

Weisser, Maren; Demel, Uta M; Stein, Stefan; Chen-Wichmann, Linping; Touzot, Fabien; Santilli, Giorgia; Sujer, Stefanie; Brendel, Christian; Siler, Ulrich; Cavazzana, Marina; Thrasher, Adrian J; Reichenbach, Janine; Essers, Marieke A G; Schwäble, Joachim; Grez, Manuel.

J Allergy Clin Immunol ; 138(1): 219-228.e9, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-26853280

7.

Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response.

Ehninger, Armin; Boch, Tobias; Uckelmann, Hannah; Essers, Marieke A; Müdder, Katja; Sleckman, Barry P; Trumpp, Andreas.

Blood ; 123(25): 3909-13, 2014 Jun 19.

Artigo em Inglês | MEDLINE | ID: mdl-24795346

8.

IFNalpha activates dormant haematopoietic stem cells in vivo.

Essers, Marieke A G; Offner, Sandra; Blanco-Bose, William E; Waibler, Zoe; Kalinke, Ulrich; Duchosal, Michel A; Trumpp, Andreas.

Nature ; 458(7240): 904-8, 2009 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-19212321

9.

Single-cell time series analysis reveals the dynamics of HSPC response to inflammation.

Bouman, Brigitte J; Demerdash, Yasmin; Sood, Shubhankar; Grünschläger, Florian; Pilz, Franziska; Itani, Abdul R; Kuck, Andrea; Marot-Lassauzaie, Valérie; Haas, Simon; Haghverdi, Laleh; Essers, Marieke Ag.

Life Sci Alliance ; 7(3)2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38110222

10.

A role for IFN during embryonic hematopoiesis.

Essers, Marieke A G.

Blood ; 128(2): 150-2, 2016 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-27418623

11.

Recent advances in understanding the impact of infection and inflammation on hematopoietic stem and progenitor cells.

Milsom, Michael D; Essers, Marieke A G.

Cells Dev ; 174: 203844, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37100116

12.

A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo.

Demel, Uta Margareta; Lutz, Raphael; Sujer, Stefanie; Demerdash, Yasmin; Sood, Shubhankar; Grünschläger, Florian; Kuck, Andrea; Werner, Paula; Blaszkiewicz, Sandra; Uckelmann, Hannah Julia; Haas, Simon; Essers, Marieke Alida Gertruda.

Blood Adv ; 6(11): 3513-3528, 2022 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-35413096

13.

Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output.

Rommel, Marcel G E; Walz, Lisa; Fotopoulou, Foteini; Kohlscheen, Saskia; Schenk, Franziska; Miskey, Csaba; Botezatu, Lacramioara; Krebs, Yvonne; Voelker, Iris M; Wittwer, Kevin; Holland-Letz, Tim; Ivics, Zoltán; von Messling, Veronika; Essers, Marieke A G; Milsom, Michael D; Pfaller, Christian K; Modlich, Ute.

Cell Rep ; 41(1): 111447, 2022 10 04.

Artigo em Inglês | MEDLINE | ID: mdl-36198277

14.

Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion.

Stalmann, Ursula S A; Ticconi, Fabio; Snoeren, Inge A M; Li, Ronghui; Gleitz, Hélène F E; Cowley, Glenn S; McConkey, Marie E; Wong, Aaron B; Schmitz, Stephani; Fuchs, Stijn N R; Sood, Shubhankar; Leimkühler, Nils B; Martinez-Høyer, Sergio; Banjanin, Bella; Root, David; Brümmendorf, Tim H; Pearce, Juliette E; Schuppert, Andreas; Bindels, Eric M J; Essers, Marieke A; Heckl, Dirk; Stiehl, Thomas; Costa, Ivan G; Ebert, Benjamin L; Schneider, Rebekka K.

Blood Adv ; 6(6): 1780-1796, 2022 03 22.

Artigo em Inglês | MEDLINE | ID: mdl-35016204

15.

Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.

Bogeska, Ruzhica; Mikecin, Ana-Matea; Kaschutnig, Paul; Fawaz, Malak; Büchler-Schäff, Marleen; Le, Duy; Ganuza, Miguel; Vollmer, Angelika; Paffenholz, Stella V; Asada, Noboru; Rodriguez-Correa, Esther; Frauhammer, Felix; Buettner, Florian; Ball, Melanie; Knoch, Julia; Stäble, Sina; Walter, Dagmar; Petri, Amelie; Carreño-Gonzalez, Martha J; Wagner, Vinona; Brors, Benedikt; Haas, Simon; Lipka, Daniel B; Essers, Marieke A G; Weru, Vivienn; Holland-Letz, Tim; Mallm, Jan-Philipp; Rippe, Karsten; Krämer, Stephan; Schlesner, Matthias; McKinney Freeman, Shannon; Florian, Maria Carolina; King, Katherine Y; Frenette, Paul S; Rieger, Michael A; Milsom, Michael D.

Cell Stem Cell ; 29(8): 1273-1284.e8, 2022 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-35858618

16.

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.

Hernández-Malmierca, Pablo; Vonficht, Dominik; Schnell, Alexandra; Uckelmann, Hannah J; Bollhagen, Alina; Mahmoud, Mohamed A A; Landua, Sophie-Luise; van der Salm, Elise; Trautmann, Christine L; Raffel, Simon; Grünschläger, Florian; Lutz, Raphael; Ghosh, Michael; Renders, Simon; Correia, Nádia; Donato, Elisa; Dixon, Karin O; Hirche, Christoph; Andresen, Carolin; Robens, Claudia; Werner, Paula S; Boch, Tobias; Eisel, David; Osen, Wolfram; Pilz, Franziska; Przybylla, Adriana; Klein, Corinna; Buchholz, Frank; Milsom, Michael D; Essers, Marieke A G; Eichmüller, Stefan B; Hofmann, Wolf-Karsten; Nowak, Daniel; Hübschmann, Daniel; Hundemer, Michael; Thiede, Christian; Bullinger, Lars; Müller-Tidow, Carsten; Armstrong, Scott A; Trumpp, Andreas; Kuchroo, Vijay K; Haas, Simon.

Cell Stem Cell ; 29(5): 760-775.e10, 2022 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-35523139

17.

Yin and Yang: The dual effects of interferons on hematopoiesis.

Demerdash, Yasmin; Kain, Bailee; Essers, Marieke A G; King, Katherine Y.

Exp Hematol ; 96: 1-12, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33571568

18.

The Hematopoietic Bone Marrow Niche Ecosystem.

Fröbel, Julia; Landspersky, Theresa; Percin, Gülce; Schreck, Christina; Rahmig, Susann; Ori, Alessandro; Nowak, Daniel; Essers, Marieke; Waskow, Claudia; Oostendorp, Robert A J.

Front Cell Dev Biol ; 9: 705410, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34368155

19.

Inflammation's Epigenetic Footprint in Hematopoietic Stem Cells.

Geiger, Sarah S; Essers, Marieke A G.

Cell Stem Cell ; 26(5): 611-612, 2020 05 07.

Artigo em Inglês | MEDLINE | ID: mdl-32386549

20.

Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs.

Pein, Maren; Insua-Rodríguez, Jacob; Hongu, Tsunaki; Riedel, Angela; Meier, Jasmin; Wiedmann, Lena; Decker, Kristin; Essers, Marieke A G; Sinn, Hans-Peter; Spaich, Saskia; Sütterlin, Marc; Schneeweiss, Andreas; Trumpp, Andreas; Oskarsson, Thordur.

Nat Commun ; 11(1): 1494, 2020 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-32198421

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