Detalhe da pesquisa
1.
A next generation FVIII mimetic bispecific antibody, Mim8, the impact on non-factor VIII related haemostasis assays.
Haemophilia
; 29(6): 1633-1637, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37824563
2.
Measuring factor VIII activity in samples from patients treated with N8-GP (Esperoct® ; turoctocog alfa pegol) during the pathfinder clinical trials programme.
Haemophilia
; 27(3): e389-e392, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314455
3.
An overview of turoctocog alfa pegol (N8-GP; ESPEROCT® ) assay performance: Implications for postadministration monitoring.
Haemophilia
; 26(1): 156-163, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31809565
4.
Evaluation of N8-GP Activity Using a One-Stage Clotting Assay: A Single-Center Experience.
Acta Haematol
; 143(5): 504-508, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31639805
5.
Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis.
Blood
; 129(15): 2161-2171, 2017 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039188
6.
FIXing postinfusion monitoring: Assay experiences with N9-GP (nonacog beta pegol; Refixia® ; Rebinyn® ).
Haemophilia
; 25(1): 154-161, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30664825
7.
A field study evaluating the activity of N8-GP in spiked plasma samples at clinical haemostasis laboratories.
Haemophilia
; 25(5): 893-901, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31294905
8.
Evaluating the thrombin generation profiles of four different rFVIII products in FVIII-deficient plasma using FIXa and FXIa activation.
Haemophilia
; 24(5): 815-822, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30112856
9.
A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.
Blood
; 121(11): 2108-16, 2013 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23335368
10.
Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model.
Blood
; 119(24): 5871-8, 2012 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563084
11.
Turoctocog alfa (NovoEight®)--from design to clinical proof of concept.
Eur J Haematol
; 93(5): 369-76, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24797664
12.
Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide.
Blood
; 118(8): 2333-41, 2011 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21700771
13.
In vitro effects of combining Mim8 with factor VIII, FVIIa, and activated prothrombin complex concentrates in thrombin generation assays.
J Thromb Haemost
; 21(6): 1493-1502, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037699
14.
The effect of a next generation factor VIII mimetic bispecific antibody (Mim8) on assays of factor VIII activity and thrombin generation.
J Thromb Haemost
; 21(3): 480-487, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696203
15.
Vatreptacog alfa from conception to clinical proof of concept.
Semin Thromb Hemost
; 38(3): 274-81, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22510860
16.
Intravascular inhibition of factor VIIa and the analogue NN1731 by antithrombin.
Br J Haematol
; 152(1): 99-107, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21083658
17.
Successful treatment of canine hemophilia by continuous expression of canine FVIIa.
Blood
; 113(16): 3682-9, 2009 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19109232
18.
rFVIIa and NN1731 reduce bleeding in hydroxyethyl starch hemodiluted rabbits.
J Trauma
; 69(5): 1196-202, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20032791
19.
Whole blood coagulation in children with thrombocytopenia and the response to platelet replacement, recombinant factor VIIa, and a potent factor VIIa analogue.
Br J Haematol
; 144(1): 99-106, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19016728
20.
Plasma elimination kinetics for factor VII are independent of its activation to factor VIIa and complex formation with plasma inhibitors.
Thromb Haemost
; 101(5): 818-26, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19404533