Detalhe da pesquisa
1.
ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis.
Hum Mol Genet
; 32(14): 2386-2398, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37220877
2.
TDP-43 is a ubiquitylation substrate of the SCFcyclin F complex.
Neurobiol Dis
; 167: 105673, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35231559
3.
SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS.
J Cell Sci
; 131(11)2018 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29748379
4.
Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity.
ACS Chem Neurosci
; 13(16): 2371-2379, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35900338
5.
Mutant Cu/Zn Superoxide Dismutase (A4V) Turnover Is Altered in Cells Containing Inclusions.
Front Mol Neurosci
; 14: 771911, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34803609
6.
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background.
Sci Rep
; 11(1): 19392, 2021 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34588483
7.
Proteome Homeostasis Dysfunction: A Unifying Principle in ALS Pathogenesis.
Trends Neurosci
; 43(5): 274-284, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32353332
8.
Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS.
iScience
; 23(11): 101700, 2020 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33196025
9.
CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper-Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding.
ACS Chem Neurosci
; 10(3): 1555-1564, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30462490
10.
The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.
Cells
; 8(6)2019 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31200561
11.
Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells.
Sci Rep
; 8(1): 15590, 2018 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30349065
12.
Ubiquitin homeostasis disruption, a common cause of proteostasis collapse in amyotrophic lateral sclerosis?
Neural Regen Res
; 17(10): 2218-2220, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35259837
13.
Addition of exogenous SOD1 aggregates causes TDP-43 mislocalisation and aggregation.
Cell Stress Chaperones
; 22(6): 893-902, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28560609
14.
Flow cytometric measurement of the cellular propagation of TDP-43 aggregation.
Prion
; 11(3): 195-204, 2017 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28486039
15.
Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies.
PLoS One
; 10(6): e0130036, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26103636
16.
Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions.
Sci Rep
; 5: 13416, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26293199