Detalhe da pesquisa
1.
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs.
Antimicrob Agents Chemother
; 67(3): e0149322, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36786609
2.
Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice.
Int J Mol Sci
; 23(12)2022 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35742960
3.
Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
Pharm Res
; 38(1): 127-140, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33559045
4.
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model.
Int J Mol Sci
; 21(21)2020 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33153231
5.
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
Mol Pharm
; 16(3): 1282-1293, 2019 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30694684
6.
[18F]Fluoroalkyl azides for rapid radiolabeling and (Re)investigation of their potential towards in vivo click chemistry.
Org Biomol Chem
; 15(28): 5976-5982, 2017 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678258
7.
Design, Synthesis, and Evaluation of a Low-Molecular-Weight (11)C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry.
Bioconjug Chem
; 27(7): 1707-12, 2016 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27308894
8.
Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-ß-d-allofuranosyl)-2-nitroimidazole (ß-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
Bioorg Med Chem
; 24(21): 5326-5339, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27614920
9.
Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.
Mol Pharm
; 12(9): 3214-25, 2015 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26202880
10.
Development of a (18) F-labeled tetrazine with favorable pharmacokinetics for bioorthogonal PET imaging.
Angew Chem Int Ed Engl
; 53(36): 9655-9, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24989029
11.
[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier.
J Cereb Blood Flow Metab
; 44(1): 142-152, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37728771
12.
Functionalization of 68Ga-Radiolabeled Nanodiamonds with Octreotide Does Not Improve Tumor-Targeting Capabilities.
Pharmaceuticals (Basel)
; 17(4)2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675474
13.
Neutrophil extracellular traps induce persistent lung tissue damage via thromboinflammation without altering virus resolution in a mouse coronavirus model.
J Thromb Haemost
; 22(1): 188-198, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37748582
14.
Effect of budesonide on pulmonary activity of multidrug resistance-associated protein 1 assessed with PET imaging in rats.
Eur J Pharm Sci
; 184: 106414, 2023 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36858275
15.
Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats.
Eur J Pharm Sci
; 183: 106404, 2023 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36773747
16.
Synthesis, radiolabeling, and preclinical in vivo evaluation of 68Ga-radiolabelled nanodiamonds.
Nucl Med Biol
; 116-117: 108310, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36565646
17.
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats.
J Control Release
; 342: 44-52, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34971693
18.
Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats.
J Control Release
; 349: 109-117, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35798092
19.
Innate Immune Training with Bacterial Extracts Enhances Lung Macrophage Recruitment to Protect from Betacoronavirus Infection.
J Innate Immun
; 14(4): 293-305, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34775384
20.
Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice.
Pharmaceutics
; 13(8)2021 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34452247