Detalhe da pesquisa
1.
Intratumor MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissue correlates with CREB signaling and distinct target gene signatures.
Exp Mol Pathol
; 105(1): 23-31, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29852183
2.
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Proc Natl Acad Sci U S A
; 106(2): 381-6, 2009 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19122148
3.
Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
J Neurochem
; 108(5): 1198-207, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19141082
4.
Clioquinol inhibits peroxide-mediated toxicity through up-regulation of phosphoinositol-3-kinase and inhibition of p53 activity.
Int J Biochem Cell Biol
; 40(5): 1030-42, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18160328
5.
Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.
Int J Biochem Cell Biol
; 40(9): 1901-17, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18346929
6.
Clioquinol promotes cancer cell toxicity through tumor necrosis factor alpha release from macrophages.
J Pharmacol Exp Ther
; 324(1): 360-7, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17940196
7.
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
Biochem J
; 407(3): 435-50, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17680773
8.
Investigating Neural Stem Cell and Glioma Stem Cell Self-renewal Potential Using Extreme Limiting Dilution Analysis (ELDA).
Bio Protoc
; 8(17): e2991, 2018 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34395790
9.
PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein.
Neuro Oncol
; 20(10): 1344-1355, 2018 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29718345
10.
Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity.
PLoS One
; 12(2): e0172791, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28241049
11.
Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signaling.
Cell Death Dis
; 7(12): e2494, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27906173
12.
Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease.
PLoS One
; 6(3): e17669, 2011 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21412423
13.
Zinc induces depletion and aggregation of endogenous TDP-43.
Free Radic Biol Med
; 48(9): 1152-61, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20138212
14.
Sustained activation of glial cell epidermal growth factor receptor by bis(thiosemicarbazonato) metal complexes is associated with inhibition of protein tyrosine phosphatase activity.
J Med Chem
; 52(21): 6606-20, 2009 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19807095
15.
The role of metals in modulating metalloprotease activity in the AD brain.
Eur Biophys J
; 37(3): 315-21, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18270696