Detalhe da pesquisa
1.
Combining monoamine oxidase B and semicarbazide-sensitive amine oxidase enzyme inhibition to address inflammatory disease.
Bioorg Med Chem Lett
; 74: 128942, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35973549
2.
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.
J Cell Mol Med
; 23(3): 1759-1770, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30536539
3.
PXS-4681A, a potent and selective mechanism-based inhibitor of SSAO/VAP-1 with anti-inflammatory effects in vivo.
J Pharmacol Exp Ther
; 347(2): 365-74, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23943052
4.
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Nat Cancer
; 4(9): 1326-1344, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37640930
5.
Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis.
Nat Commun
; 13(1): 5555, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36138009
6.
The Au(I)-catalyzed intramolecular hydroarylation of terminal alkynes under mild conditions: application to the synthesis of 2H-chromenes, coumarins, benzofurans, and dihydroquinolines.
J Org Chem
; 74(22): 8901-3, 2009 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19848386
7.
Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.
J Med Chem
; 62(21): 9874-9889, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31580073
8.
Total synthesis of (-)-spirangien A and its methyl ester.
Chem Commun (Camb)
; (47): 6408-10, 2008 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19048171
9.
Synthetic Studies on the Natural Product Myrsinoic Acid F Reveal Biologically Active Analogues.
Org Lett
; 20(13): 3984-3987, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29888922
10.
Author Correction: Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis.
Nat Commun
; 14(1): 135, 2023 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627321
11.
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
Oncotarget
; 8(16): 26066-26078, 2017 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199967
12.
Total synthesis and stereochemical reassignment of (+)-dolastatin 19.
Org Lett
; 8(10): 2131-4, 2006 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16671799
13.
The mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF-ß1 pathway in human lung fibroblasts.
Immunol Lett
; 165(2): 90-101, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25929803
14.
Synthesis of an advanced C10-C32 spiroacetal fragment and assignment of the absolute configuration of spirangien A.
Angew Chem Int Ed Engl
; 46(35): 6699-702, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17665392
15.
A chemoenzymatic total synthesis of (+)-amabiline.
Org Lett
; 11(14): 3160-2, 2009 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19586069
16.
Total synthesis of (-)-spirangien A, an antimitotic polyketide isolated from the myxobacterium Sorangium cellulosum.
Chem Asian J
; 4(4): 594-611, 2009 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19173216