Detalhe da pesquisa
1.
Human dental pulp cells modulate CD8+ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro.
Cell Immunol
; 380: 104589, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36084401
2.
cADPR Does Not Activate TRPM2.
Int J Mol Sci
; 23(6)2022 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35328585
3.
Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation.
Biochem Soc Trans
; 47(1): 329-337, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30674608
4.
2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist.
Nat Chem Biol
; 13(9): 1036-1044, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671679
5.
Synthesis of Terminal Ribose Analogues of Adenosine 5'-Diphosphate Ribose as Probes for the Transient Receptor Potential Cation Channel TRPM2.
J Org Chem
; 84(10): 6143-6157, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30978018
6.
P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP.
Purinergic Signal
; 15(2): 155-166, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31016551
7.
Mag-Fluo4 in T cells: Imaging of intra-organelle free Ca2+ concentrations.
Biochim Biophys Acta Mol Cell Res
; 1864(6): 977-986, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913206
8.
Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
Biochem J
; 474(13): 2159-2175, 2017 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28515263
9.
Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by ß-adrenergic stimulation.
J Biol Chem
; 288(22): 16017-30, 2013 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23564460
10.
2'-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca2+ concentrations.
Front Immunol
; 15: 1294357, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38318185
11.
Nicotinic acid adenine dinucleotide phosphate (NAADP) degradation by alkaline phosphatase.
J Biol Chem
; 287(39): 32525-34, 2012 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22851169
12.
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin.
Int J Oncol
; 62(1)2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36382671
13.
Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope.
J Biol Chem
; 286(6): 4500-10, 2011 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21148483
14.
The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn2+ -binding domain essential for structural integrity and channel activity.
Protein Sci
; 31(6): e4320, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35634784
15.
Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities.
J Biol Chem
; 285(8): 5541-54, 2010 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20022963
16.
Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9.
FEBS J
; 288(23): 6769-6782, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34189846
17.
Mouse CD38-Specific Heavy Chain Antibodies Inhibit CD38 GDPR-Cyclase Activity and Mediate Cytotoxicity Against Tumor Cells.
Front Immunol
; 12: 703574, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34539634
18.
CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression.
Nat Commun
; 12(1): 5911, 2021 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34625545
19.
HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation.
Sci Signal
; 14(675)2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758062
20.
8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist.
Biochem J
; 422(1): 139-49, 2009 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19492987