Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

TR(i)P Goes On: Auxiliary TRP Channel Subunits?

Flockerzi, Veit; Fakler, Bernd.

Circ Res ; 134(4): 346-350, 2024 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-38359093

2.

TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect G_q/11-G_i/o coincidence signals of variable strengths.

Tian, Jin-Bin; Yang, Jane; Joslin, William C; Flockerzi, Veit; Prescott, Steven A; Birnbaumer, Lutz; Zhu, Michael X.

Proc Natl Acad Sci U S A ; 119(20): e2120870119, 2022 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-35544691

3.

Reconstitution of ß-adrenergic regulation of Ca_V1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.

Katz, Moshe; Subramaniam, Suraj; Chomsky-Hecht, Orna; Tsemakhovich, Vladimir; Flockerzi, Veit; Klussmann, Enno; Hirsch, Joel A; Weiss, Sharon; Dascal, Nathan.

Proc Natl Acad Sci U S A ; 118(21)2021 05 25.

Artigo em Inglês | MEDLINE | ID: mdl-34001616

4.

Englerin A Inhibits T-Type Voltage-Gated Calcium Channels at Low Micromolar Concentrations.

Wardas, Barbara; Schneider, Jochen G; Klugbauer, Norbert; Flockerzi, Veit; Beck, Andreas.

Mol Pharmacol ; 104(4): 144-153, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37399325

5.

Human airway tuft cells influence the mucociliary clearance through cholinergic signalling.

Hollenhorst, Monika I; Husnik, Thomas; Zylka, Malin; Duda, Nele; Flockerzi, Veit; Tschernig, Thomas; Maxeiner, Stephan; Krasteva-Christ, Gabriela.

Respir Res ; 24(1): 267, 2023 Nov 04.

Artigo em Inglês | MEDLINE | ID: mdl-37925434

6.

Outside the limit: questioning the distance restrictions for cooperative miRNA binding sites.

Diener, Caroline; Hart, Martin; Fecher-Trost, Claudia; Knittel, Jessica; Rheinheimer, Stefanie; Meyer, Markus R; Mayer, Jens; Flockerzi, Veit; Keller, Andreas; Meese, Eckart.

Cell Mol Biol Lett ; 28(1): 8, 2023 Jan 24.

Artigo em Inglês | MEDLINE | ID: mdl-36694129

7.

Activity of the yeast vacuolar TRP channel TRPY1 is inhibited by Ca²⁺-calmodulin binding.

Amini, Mahnaz; Chang, Yiming; Wissenbach, Ulrich; Flockerzi, Veit; Schlenstedt, Gabriel; Beck, Andreas.

J Biol Chem ; 297(4): 101126, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34461097

8.

Stimulation of the EP₃ receptor causes lung oedema by activation of TRPC6 in pulmonary endothelial cells.

Jiang, Tian; Samapati, Rudi; Klassen, Sergej; Lei, Disi; Erfinanda, Lasti; Jankowski, Vera; Simmons, Szandor; Yin, Jun; Arenz, Christoph; Dietrich, Alexander; Gudermann, Thomas; Adam, Dieter; Schaefer, Michael; Jankowski, Joachim; Flockerzi, Veit; Nüsing, Rolf; Uhlig, Stefan; Kuebler, Wolfgang M.

Eur Respir J ; 60(4)2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35450969

9.

TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses.

Schwarz, Yvonne; Oleinikov, Katharina; Schindeldecker, Barbara; Wyatt, Amanda; Weißgerber, Petra; Flockerzi, Veit; Boehm, Ulrich; Freichel, Marc; Bruns, Dieter.

PLoS Biol ; 17(9): e3000445, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31536487

10.

A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy.

Wierer, Michael; Werner, Julia; Wobst, Jana; Kastrati, Adnan; Cepele, Ganildo; Aherrahrou, Redouane; Sager, Hendrik B; Erdmann, Jeanette; Dichgans, Martin; Flockerzi, Veit; Civelek, Mete; Dietrich, Alexander; Mann, Matthias; Schunkert, Heribert; Kessler, Thorsten.

Eur Heart J ; 42(18): 1773-1785, 2021 05 07.

Artigo em Inglês | MEDLINE | ID: mdl-33829256

11.

L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.

Hofmann, Franz; Flockerzi, Veit; Kahl, Sabine; Wegener, Jörg W.

Physiol Rev ; 94(1): 303-26, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24382889

12.

Development of an AAV9-RNAi-mediated silencing strategy to abrogate TRPM4 expression in the adult heart.

Medert, Rebekka; Jungmann, Andreas; Hildebrand, Staffan; Busch, Martin; Grimm, Dirk; Flockerzi, Veit; Müller, Oliver J; Most, Patrick; Schumacher, Dagmar; Freichel, Marc.

Pflugers Arch ; 473(3): 533-546, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33580817

13.

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.

Bröker-Lai, Jenny; Kollewe, Astrid; Schindeldecker, Barbara; Pohle, Jörg; Nguyen Chi, Vivan; Mathar, Ilka; Guzman, Raul; Schwarz, Yvonne; Lai, Alan; Weißgerber, Petra; Schwegler, Herbert; Dietrich, Alexander; Both, Martin; Sprengel, Rolf; Draguhn, Andreas; Köhr, Georg; Fakler, Bernd; Flockerzi, Veit; Bruns, Dieter; Freichel, Marc.

EMBO J ; 36(18): 2770-2789, 2017 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-28790178

14.

Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels.

Jha, Mithilesh K; Badou, Abdallah; Meissner, Marcel; McRory, John E; Freichel, Marc; Flockerzi, Veit; Flavell, Richard A.

Nat Immunol ; 10(12): 1275-82, 2009 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-19838200

15.

Domain zipping and unzipping modulates TRPM4's properties in human cardiac conduction disease.

Xian, Wenying; Wang, Hongmei; Moretti, Alessandra; Laugwitz, Karl-Ludwig; Flockerzi, Veit; Lipp, Peter.

FASEB J ; 34(9): 12114-12126, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32681584

16.

Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling.

Hollenhorst, Monika I; Jurastow, Innokentij; Nandigama, Rajender; Appenzeller, Silke; Li, Lei; Vogel, Jörg; Wiederhold, Stephanie; Althaus, Mike; Empting, Martin; Altmüller, Janine; Hirsch, Anna K H; Flockerzi, Veit; Canning, Brendan J; Saliba, Antoine-Emmanuel; Krasteva-Christ, Gabriela.

FASEB J ; 34(1): 316-332, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31914675

17.

Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systems.

Gampfer, Tanja M; Wagmann, Lea; Belkacemi, Anouar; Flockerzi, Veit; Meyer, Markus R.

Arch Toxicol ; 95(11): 3539-3557, 2021 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-34453555

18.

Toxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts.

Manier, Sascha K; Wagmann, Lea; Flockerzi, Veit; Meyer, Markus R.

Arch Toxicol ; 94(6): 2047-2059, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32313995

19.

Transient Receptor Potential Vanilloid 6 (TRPV6) Proteins Control the Extracellular Matrix Structure of the Placental Labyrinth.

Winter, Manuel; Weissgerber, Petra; Klein, Karolin; Lux, Femke; Yildiz, Daniela; Wissenbach, Ulrich; Philipp, Stephan E; Meyer, Markus R; Flockerzi, Veit; Fecher-Trost, Claudia.

Int J Mol Sci ; 21(24)2020 Dec 18.

Artigo em Inglês | MEDLINE | ID: mdl-33352987

20.

Identification and characterization of hydrophobic gate residues in TRP channels.

Zheng, Wang; Hu, Ruikun; Cai, Ruiqi; Hofmann, Laura; Hu, Qiaolin; Fatehi, Mohammad; Long, Wentong; Kong, Tim; Tang, Jingfeng; Light, Peter; Flockerzi, Veit; Cao, Ying; Chen, Xing-Zhen.

FASEB J ; 32(2): 639-653, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-28970257

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