Detalhe da pesquisa
1.
Quantifying KRAS G12C Covalent Drug Inhibitor Activity in Mouse Tumors Using Mass Spectrometry.
Anal Chem
; 95(11): 4834-4839, 2023 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36876898
2.
USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature
; 550(7677): 534-538, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045385
3.
MiDAS-Meaningful Immunogenetic Data at Scale.
PLoS Comput Biol
; 17(7): e1009131, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34228721
4.
Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes.
Drug Metab Dispos
; 49(9): 760-769, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34187837
5.
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration.
Proc Natl Acad Sci U S A
; 115(50): E11701-E11710, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30463956
6.
Characterizing and Quantitating Therapeutic Tethered Multimeric Antibody Degradation Using Affinity Capture Mass Spectrometry.
Anal Chem
; 92(10): 6839-6843, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32309925
7.
Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms.
Genes Immun
; 20(2): 172-179, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29550837
8.
Dual functionality of ß-tryptase protomers as both proteases and cofactors in the active tetramer.
J Biol Chem
; 293(25): 9614-9628, 2018 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661938
9.
Identifying and mitigating batch effects in whole genome sequencing data.
BMC Bioinformatics
; 18(1): 351, 2017 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28738841
10.
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma.
Proc Natl Acad Sci U S A
; 111(39): 14217-22, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25225364
11.
Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling.
Proc Natl Acad Sci U S A
; 110(28): 11379-84, 2013 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23801757
12.
Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents.
Breast Cancer Res
; 17: 59, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25902869
13.
PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition.
J Pathol
; 234(4): 502-13, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25074413
14.
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis.
Cancer Cell
; 9(3): 157-73, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16530701
15.
In situ validation of an intestinal stem cell signature in colorectal cancer.
Gut
; 62(7): 1012-23, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22637696
16.
Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.
J Pathol
; 227(4): 417-30, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22611036
17.
Complementary proteomic tools for the dissection of apoptotic proteolysis events.
J Proteome Res
; 11(5): 2947-54, 2012 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22432722
18.
A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.
Sci Rep
; 12(1): 5574, 2022 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35368043
19.
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy.
Cancer Discov
; 12(1): 204-219, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34544753
20.
Ocular phenotypes in a mouse model of impaired glucocerebrosidase activity.
Sci Rep
; 11(1): 6079, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33727605