Detalhe da pesquisa
1.
Pharmacological modulation of brain activity in a preclinical model of osteoarthritis.
Neuroimage
; 64: 341-55, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982372
2.
Monitoring tumor response to linifanib therapy with SPECT/CT using the integrin αvß3-targeted radiotracer 99mTc-3P-RGD2.
J Pharmacol Exp Ther
; 346(2): 251-8, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23750021
3.
Neutralizing RGMa with Elezanumab Promotes Cerebroprotection and Recovery in Rabbit Middle Cerebral Artery Occlusion.
Transl Stroke Res
; 2023 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37326791
4.
Xanomeline modulation of the blood oxygenation level-dependent signal in awake rats: development of pharmacological magnetic resonance imaging as a translatable pharmacodynamic biomarker for central activity and dose selection.
J Pharmacol Exp Ther
; 341(1): 263-73, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22267203
5.
Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.
J Pharmacol Exp Ther
; 343(1): 233-45, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815533
6.
Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.
J Pharmacol Exp Ther
; 336(3): 709-15, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21172908
7.
ABT-869, a multitargeted receptor tyrosine kinase inhibitor, reduces tumor microvascularity and improves vascular wall integrity in preclinical tumor models.
J Pharmacol Exp Ther
; 338(1): 134-42, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21505059
8.
Pharmacokinetic modeling and [¹²³]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089.
J Pharmacol Exp Ther
; 336(3): 716-23, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21172907
9.
Structural abnormalities revealed by magnetic resonance imaging in rats prenatally exposed to methylazoxymethanol acetate parallel cerebral pathology in schizophrenia.
Synapse
; 65(5): 393-403, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20803618
10.
Magnetic resonance imaging detection and time course of cerebral microhemorrhages during passive immunotherapy in living amyloid precursor protein transgenic mice.
J Pharmacol Exp Ther
; 335(3): 580-8, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20823195
11.
Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imaging.
J Pharmacol Exp Ther
; 328(1): 141-51, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18931146
12.
ABT-751, a novel tubulin-binding agent, decreases tumor perfusion and disrupts tumor vasculature.
Anticancer Drugs
; 20(6): 483-92, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19398903
13.
Cognitive endpoints as disease biomarkers: optimizing the congruency of preclinical models to the clinic.
Curr Opin Investig Drugs
; 9(7): 696-706, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18600575
14.
Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.
J Med Chem
; 50(22): 5439-48, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17918921
15.
Differential effects of ciproxifan and nicotine on impulsivity and attention measures in the 5-choice serial reaction time test.
Biochem Pharmacol
; 73(8): 1123-34, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17214974
16.
Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.
Biochem Pharmacol
; 73(8): 1243-55, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17371699
17.
The drug-induced helplessness test: an animal assay for assessing behavioral despair in response to neuroleptic treatment.
Psychopharmacology (Berl)
; 190(1): 1-11, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17093979
18.
Molecular imaging in oncology drug development.
Drug Discov Today
; 22(1): 140-147, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693713
19.
Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats.
Neuropsychopharmacology
; 31(7): 1382-92, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16395300
20.
Lack of efficacy of melanin-concentrating hormone-1 receptor antagonists in models of depression and anxiety.
Eur J Pharmacol
; 540(1-3): 115-20, 2006 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16765941