Detalhe da pesquisa
1.
Reduced Tolerance and Asymmetrical Crosstolerance to Effects of the Indole Quinuclidinone Analog PNR-4-20, a G Protein-Biased Cannabinoid 1 Receptor Agonist in Mice: Comparisons with Δ9-Tetrahydrocannabinol and JWH-018.
J Pharmacol Exp Ther
; 369(2): 259-269, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833484
2.
The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects.
Toxicol Appl Pharmacol
; 353: 31-42, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29906493
3.
Characterization of structurally novel G protein biased CB1 agonists: Implications for drug development.
Pharmacol Res
; 125(Pt B): 161-177, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28838808
4.
CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen.
Biochem Biophys Res Commun
; 441(2): 339-43, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24148245
5.
Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors.
Toxicol Appl Pharmacol
; 269(2): 100-8, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23537664
6.
Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development.
Life Sci
; 285: 119993, 2021 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34592231
7.
Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC.
Front Pharmacol
; 9: 1084, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30319418
8.
Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity.
Front Pharmacol
; 7: 503, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28066250
9.
Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development.
PLoS One
; 11(12): e0167240, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27936172
10.
Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole quinuclidine analogs.
Eur J Pharmacol
; 737: 140-8, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24858620
11.
Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse.
J Med Chem
; 56(11): 4537-50, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23631463
12.
AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: implications for opioid/cannabinoid interaction studies.
Neuropharmacology
; 63(5): 905-15, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22771770