Detalhe da pesquisa
1.
Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis.
J Enzyme Inhib Med Chem
; 39(1): 2301772, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38221792
2.
Structure-Based Design and Pharmacophore-Based Virtual Screening of Combinatorial Library of Triclosan Analogues Active against Enoyl-Acyl Carrier Protein Reductase of Plasmodium falciparum with Favourable ADME Profiles.
Int J Mol Sci
; 24(8)2023 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108083
3.
Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology.
J Transl Med
; 17(1): 330, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31570112
4.
Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone-chalcone and isatin-chalcone inhibitors probing the S2 active site pocket.
J Enzyme Inhib Med Chem
; 34(1): 547-561, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30696325
5.
Structure-Based Design and in Silico Screening of Virtual Combinatorial Library of Benzamides Inhibiting 2-trans Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Predicted Pharmacokinetic Profiles.
Int J Mol Sci
; 20(19)2019 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31554227
6.
Stereoisomers of oseltamivir - synthesis, in silico prediction and biological evaluation.
Org Biomol Chem
; 15(8): 1828-1841, 2017 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28155963
7.
Computer-Aided Design of Orally Bioavailable Pyrrolidine Carboxamide Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Pharmacokinetic Profiles.
Int J Mol Sci
; 16(12): 29744-71, 2015 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26703572
8.
Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors.
Bioorg Med Chem
; 21(1): 257-68, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23199481
9.
Synthesis and in vitro study of novel neuraminidase inhibitors against avian influenza virus.
Bioorg Med Chem
; 20(6): 2152-7, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342267
10.
Molecular interfaces of the galactose-binding protein Tectonin domains in host-pathogen interaction.
J Biol Chem
; 285(13): 9898-9907, 2010 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20118243
11.
Computer-assisted combinatorial design of bicyclic thymidine analogs as inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
J Comput Aided Mol Des
; 25(1): 31-49, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21082329
12.
Theoretical prediction of drug-receptor interactions.
Drug Metabol Drug Interact
; 26(3): 91-104, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21980962
13.
Design, structure-based focusing and in silico screening of combinatorial library of peptidomimetic inhibitors of Dengue virus NS2B-NS3 protease.
J Comput Aided Mol Des
; 24(3): 195-212, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20306283
14.
Experimental validation of specificity of the squamous cell carcinoma antigen-immunoglobulin M (SCCA-IgM) assay in patients with cirrhosis.
Clin Chem Lab Med
; 48(2): 217-23, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20001440
15.
Modeling the effect of 3 missense AGXT mutations on dimerization of the AGT enzyme in primary hyperoxaluria type 1.
J Nephrol
; 23(6): 667-76, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20564000
16.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease.
RSC Adv
; 10(66): 40244-40263, 2020 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35520818
17.
Diversity of sialidases found in the human body - A review.
Int J Biol Macromol
; 148: 857-868, 2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31945439
18.
Adhesion of fibroblast cells on thin films representing surfaces of polymeric scaffolds of human urethra rationalized by molecular models of integrin binding: cell adhesion on polymeric scaffolds for regenerative medicine.
J Biotechnol
; 324: 233-238, 2020 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33157195
19.
Dynamic behavior of avian influenza A virus neuraminidase subtype H5N1 in complex with oseltamivir, zanamivir, peramivir, and their phosphonate analogues.
J Chem Inf Model
; 49(10): 2323-32, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19780597
20.
Oguchi type I caused by a homozygous missense variation in the SAG gene.
Eur J Med Genet
; 62(9): 103548, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30267901