Detalhe da pesquisa
1.
An 11-Beta Hydroxysteroid Dehydrogenase Type 1 Inhibitor, JTT-654 Ameliorates Insulin Resistance and Non-obese Type 2 Diabetes.
Biol Pharm Bull
; 46(7): 969-978, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37394647
2.
JTP-109192, a novel G protein-coupled receptor 119 agonist, prevents atherosclerosis by improving hypercholesterolaemia in congenic spontaneously hyperlipidaemic mice.
Clin Exp Pharmacol Physiol
; 48(3): 381-388, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33068442
3.
Lead generation and optimization of novel GPR119 agonists with a spirocyclic cyclohexane structure.
Bioorg Med Chem Lett
; 29(3): 373-379, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30587450
4.
Optimization of oxadiazole derivatives with a spirocyclic cyclohexane structure as novel GPR119 agonists.
Bioorg Med Chem Lett
; 29(16): 2100-2106, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31288965
5.
Chronic treatment of JTP-109192, a novel G-protein coupled receptor 119 agonist, improves metabolic abnormalities in Zucker Fatty rats.
Clin Exp Pharmacol Physiol
; 46(10): 910-919, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31380572
6.
Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure.
Bioorg Med Chem Lett
; 28(7): 1228-1233, 2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29519733
7.
Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle.
Elife
; 82019 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31545169
8.
Characterization of hepatic glucose metabolism disorder with the progress of diabetes in male Spontaneously Diabetic Torii rats.
J Vet Med Sci
; 70(11): 1239-45, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19057144
9.
Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity.
PLoS One
; 12(5): e0177516, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28498863
10.
Evidence of Notch-Hesr-Nrf2 Axis in Muscle Stem Cells, but Absence of Nrf2 Has No Effect on Their Quiescent and Undifferentiated State.
PLoS One
; 10(9): e0138517, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26418810
11.
Pharmacological effects of JTT-551, a novel protein tyrosine phosphatase 1B inhibitor, in diet-induced obesity mice.
J Diabetes Res
; 2014: 680348, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24987707
12.
Effect of food restriction on adipose tissue in spontaneously diabetic Torii fatty rats.
Exp Diabetes Res
; 2009: 715057, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19696902
13.
Pancreatic function of spontaneously diabetic torii rats in pre-diabetic stage.
Exp Anim
; 58(4): 363-74, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19654434
14.
Role of gamma delta T cells in the inflammatory response of experimental colitis mice.
J Immunol
; 171(10): 5507-13, 2003 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14607957