1.
Clin Transl Sci
; 11(5): 461-470, 2018 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29877628
RESUMO
The Assay Guidance Manual (AGM) is an eBook of best practices for the design, development, and implementation of robust assays for early drug discovery. Initiated by pharmaceutical company scientists, the manual provides guidance for designing a "testing funnel" of assays to identify genuine hits using high-throughput screening (HTS) and advancing them through preclinical development. Combined with a workshop/tutorial component, the overall goal of the AGM is to provide a valuable resource for training translational scientists.
Assuntos
Bioensaio/métodos , Descoberta de Drogas , Geografia , Ensaios de Triagem em Larga Escala , Humanos , Pesquisa Translacional Biomédica
2.
Sci Transl Med
; 5(171): 171cm1, 2013 Feb 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23390245
RESUMO
A new map is presented for creating an open, collaborative, and coordinated system for drug development.