Detalhe da pesquisa
1.
High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for the Mycobacterium tuberculosis RNA polymerase.
Nucleic Acids Res
; 51(19): e99, 2023 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37739412
2.
Mycobacterium tuberculosis DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine.
Proc Natl Acad Sci U S A
; 119(8)2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35173050
3.
Molecular dissection of RbpA-mediated regulation of fidaxomicin sensitivity in mycobacteria.
J Biol Chem
; 298(4): 101752, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35189142
4.
CarD contributes to diverse gene expression outcomes throughout the genome of Mycobacterium tuberculosis.
Proc Natl Acad Sci U S A
; 116(27): 13573-13581, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217290
5.
The Context-Dependent Influence of Promoter Sequence Motifs on Transcription Initiation Kinetics and Regulation.
J Bacteriol
; 203(8)2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139481
6.
CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase.
Nucleic Acids Res
; 47(13): 6685-6698, 2019 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127308
7.
The calculation of transcript flux ratios reveals single regulatory mechanisms capable of activation and repression.
Proc Natl Acad Sci U S A
; 115(50): E11604-E11613, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30463953
8.
Single-molecule approach for studying RNAP II transcription initiation using magnetic tweezers.
Methods
; 159-160: 35-44, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30898685
9.
Mechanisms of backtrack recovery by RNA polymerases I and II.
Proc Natl Acad Sci U S A
; 113(11): 2946-51, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26929337
10.
Domains within RbpA Serve Specific Functional Roles That Regulate the Expression of Distinct Mycobacterial Gene Subsets.
J Bacteriol
; 200(13)2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29686140
11.
Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.
Nucleic Acids Res
; 44(15): 7304-13, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27342278
12.
Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.
J Bacteriol
; 199(4)2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27920294
13.
CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism.
Nucleic Acids Res
; 43(6): 3272-85, 2015 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25697505
14.
A Kinetic Signature for Parallel Pathways: Conformational Selection and Induced Fit. Links and Disconnects between Observed Relaxation Rates and Fractional Equilibrium Flux under Pseudo-First-Order Conditions.
Biochemistry
; 55(50): 7014-7022, 2016 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27992996
15.
CarD integrates three functional modules to promote efficient transcription, antibiotic tolerance, and pathogenesis in mycobacteria.
Mol Microbiol
; 93(4): 682-97, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24962732
16.
Mycobacterium tuberculosis Ku Stimulates Multi-round DNA Unwinding by UvrD1 Monomers.
J Mol Biol
; 436(2): 168367, 2024 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972687
17.
Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner.
Nature
; 446(7137): 820-3, 2007 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17361130
18.
High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for Mycobacterium tuberculosis RNA polymerase.
bioRxiv
; 2023 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993414
19.
Parallel path mechanisms lead to nonmonotonic force-velocity curves and an optimum load for molecular motor function.
Phys Rev E
; 105(3-1): 034405, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35428051
20.
Shelterin Components Modulate Nucleic Acids Condensation and Phase Separation in the Context of Telomeric DNA.
J Mol Biol
; 434(16): 167685, 2022 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35724929