Detalhe da pesquisa
1.
Alsinol, an arylamino alcohol derivative active against Plasmodium, Babesia, Trypanosoma, and Leishmania: past and new outcomes.
Parasitol Res
; 119(10): 3503-3515, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32772176
2.
Primaquine-quinoxaline 1,4-di-N-oxide hybrids with action on the exo-erythrocytic forms of Plasmodium induce their effect by the production of reactive oxygen species.
Malar J
; 18(1): 201, 2019 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217011
3.
New hydrazine and hydrazide quinoxaline 1,4-di-N-oxide derivatives: In silico ADMET, antiplasmodial and antileishmanial activity.
Bioorg Med Chem Lett
; 27(8): 1820-1825, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28291694
4.
Synthesis, biological evaluation and structure-activity relationships of new quinoxaline derivatives as anti-Plasmodium falciparum agents.
Molecules
; 19(2): 2166-80, 2014 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24552985
5.
New amide derivatives of quinoxaline 1,4-di-N-oxide with leishmanicidal and antiplasmodial activities.
Molecules
; 18(4): 4718-27, 2013 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23609622
6.
Antiplasmodial and leishmanicidal activities of 2-cyano-3-(4-phenylpiperazine-1-carboxamido) quinoxaline 1,4-dioxide derivatives.
Molecules
; 17(8): 9451-61, 2012 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22871647
7.
New quinoxaline derivatives as potential MT1 and MT2 receptor ligands.
Molecules
; 17(7): 7737-57, 2012 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22732886
8.
New salicylamide and sulfonamide derivatives of quinoxaline 1,4-di-N-oxide with antileishmanial and antimalarial activities.
Bioorg Med Chem Lett
; 21(15): 4498-502, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21724395
9.
New 1,4-di-N-oxide-quinoxaline-2-ylmethylene isonicotinic acid hydrazide derivatives as anti-Mycobacterium tuberculosis agents.
Bioorg Med Chem Lett
; 21(12): 3699-703, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570839
10.
Aryl piperazine and pyrrolidine as antimalarial agents. Synthesis and investigation of structure-activity relationships.
Exp Parasitol
; 128(2): 97-103, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21354139
11.
Building a MCHR1 homology model provides insight into the receptor-antagonist contacts that are important for the development of new anti-obesity agents.
Bioorg Med Chem
; 18(21): 7365-79, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20932767
12.
New 1-aryl-3-substituted propanol derivatives as antimalarial agents.
Molecules
; 14(10): 4120-35, 2009 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19924051
13.
Melanin-concentrating hormone receptor 1 antagonists: a new perspective for the pharmacologic treatment of obesity.
Curr Med Chem
; 15(10): 1025-43, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18393860
14.
Novel antimalarial chloroquine- and primaquine-quinoxaline 1,4-di-N-oxide hybrids: Design, synthesis, Plasmodium life cycle stage profile, and preliminary toxicity studies.
Eur J Med Chem
; 158: 68-81, 2018 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30199706
15.
Structure-activity relationship of new antimalarial 1-aryl-3-susbtituted propanol derivatives: Synthesis, preliminary toxicity profiling, parasite life cycle stage studies, target exploration, and targeted delivery.
Eur J Med Chem
; 152: 489-514, 2018 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754074
16.
Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease.
Curr Med Chem
; 24(11): 1066-1138, 2017 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28025938
17.
ImmunoPEGliposomes for the targeted delivery of novel lipophilic drugs to red blood cells in a falciparum malaria murine model.
Biomaterials
; 145: 178-191, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28869864
18.
Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration.
Int J Parasitol Drugs Drug Resist
; 6(3): 184-198, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27718413
19.
Synthesis and evaluation of new arylsulfonamidomethylcyclohexyl derivatives as human neuropeptide Y Y5 receptor antagonists for the treatment of obesity.
Eur J Med Chem
; 39(1): 49-58, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14987833
20.
Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents.
Eur J Med Chem
; 66: 324-34, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23811257