Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells.

Medina Sanchez, Luzmariel; Siller, Magdalena; Zeng, Yanlin; Brigleb, Pamela H; Sangani, Kishan A; Soto, Ariadna S; Engl, Clarisse; Laughlin, Colin R; Rana, Mohit; Van Der Kraak, Lauren; Pandey, Surya P; Bender, Mackenzie J; Fitzgerald, Britney; Hedden, Lee; Fiske, Kay; Taylor, Gwen M; Wright, Austin P; Mehta, Isha D; Rahman, Syed A; Galipeau, Heather J; Mullett, Steven J; Gelhaus, Stacy L; Watkins, Simon C; Bercik, Premysl; Nice, Timothy J; Jabri, Bana; Meisel, Marlies; Das, Jishnu; Dermody, Terence S; Verdú, Elena F; Hinterleitner, Reinhard.

Immunity ; 56(8): 1862-1875.e9, 2023 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-37478853

2.

Non-Host Factors Influencing Onset and Severity of Celiac Disease.

Galipeau, Heather J; Hinterleitner, Reinhard; Leonard, Maureen M; Caminero, Alberto.

Gastroenterology ; 2024 Jan 28.

Artigo em Inglês | MEDLINE | ID: mdl-38286392

3.

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Meisel, Marlies; Hinterleitner, Reinhard; Pacis, Alain; Chen, Li; Earley, Zachary M; Mayassi, Toufic; Pierre, Joseph F; Ernest, Jordan D; Galipeau, Heather J; Thuille, Nikolaus; Bouziat, Romain; Buscarlet, Manuel; Ringus, Daina L; Wang, Yitang; Li, Ye; Dinh, Vu; Kim, Sangman M; McDonald, Benjamin D; Zurenski, Matthew A; Musch, Mark W; Furtado, Glaucia C; Lira, Sergio A; Baier, Gottfried; Chang, Eugene B; Eren, A Murat; Weber, Christopher R; Busque, Lambert; Godley, Lucy A; Verdú, Elena F; Barreiro, Luis B; Jabri, Bana.

Nature ; 557(7706): 580-584, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29769727

4.

Biogeographic Variation and Functional Pathways of the Gut Microbiota in Celiac Disease.

Constante, Marco; Libertucci, Josie; Galipeau, Heather J; Szamosi, Jake C; Rueda, Gaston; Miranda, Pedro M; Pinto-Sanchez, Maria Ines; Southward, Carolyn M; Rossi, Laura; Fontes, Michelle E; Chirdo, Fernando G; Surette, Michael G; Bercik, Premysl; Caminero, Alberto; Verdu, Elena F.

Gastroenterology ; 163(5): 1351-1363.e15, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-35810781

5.

Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis.

Galipeau, Heather J; Caminero, Alberto; Turpin, Williams; Bermudez-Brito, Miriam; Santiago, Alba; Libertucci, Josie; Constante, Marco; Raygoza Garay, Juan Antonio; Rueda, Gaston; Armstrong, Sarah; Clarizio, Alex; Smith, Michelle I; Surette, Michael G; Bercik, Premysl; Croitoru, Kenneth; Verdu, Elena F.

Gastroenterology ; 160(5): 1532-1545, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33310084

6.

A Riddle, Wrapped in a Mystery, Inside an Enigma: Another Key to Wheat Sensitivity?

Galipeau, Heather J; Verdu, Elena F.

Am J Gastroenterol ; 116(5): 943-945, 2021 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-33767100

7.

Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins.

Caminero, Alberto; McCarville, Justin L; Zevallos, Victor F; Pigrau, Marc; Yu, Xuechen B; Jury, Jennifer; Galipeau, Heather J; Clarizio, Alexandra V; Casqueiro, Javier; Murray, Joseph A; Collins, Stephen M; Alaedini, Armin; Bercik, Premysl; Schuppan, Detlef; Verdu, Elena F.

Gastroenterology ; 156(8): 2266-2280, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30802444

8.

Lifelong memory responses perpetuate humoral T_H2 immunity and anaphylaxis in food allergy.

Jiménez-Saiz, Rodrigo; Chu, Derek K; Mandur, Talveer S; Walker, Tina D; Gordon, Melissa E; Chaudhary, Roopali; Koenig, Joshua; Saliba, Sarah; Galipeau, Heather J; Utley, Adam; King, Irah L; Lee, Kelvin; Ettinger, Rachel; Waserman, Susan; Kolbeck, Roland; Jordana, Manel.

J Allergy Clin Immunol ; 140(6): 1604-1615.e5, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28216433

9.

Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity.

Caminero, Alberto; Galipeau, Heather J; McCarville, Justin L; Johnston, Chad W; Bernier, Steve P; Russell, Amy K; Jury, Jennifer; Herran, Alexandra R; Casqueiro, Javier; Tye-Din, Jason A; Surette, Michael G; Magarvey, Nathan A; Schuppan, Detlef; Verdu, Elena F.

Gastroenterology ; 151(4): 670-83, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27373514

10.

Intestinal microbiota modulates gluten-induced immunopathology in humanized mice.

Galipeau, Heather J; McCarville, Justin L; Huebener, Sina; Litwin, Owen; Meisel, Marlies; Jabri, Bana; Sanz, Yolanda; Murray, Joseph A; Jordana, Manel; Alaedini, Armin; Chirdo, Fernando G; Verdu, Elena F.

Am J Pathol ; 185(11): 2969-82, 2015 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-26456581

11.

Novel role of the serine protease inhibitor elafin in gluten-related disorders.

Galipeau, Heather J; Wiepjes, Michelle; Motta, Jean-Paul; Schulz, Jessica D; Jury, Jennifer; Natividad, Jane M; Pinto-Sanchez, Ines; Sinclair, Daniel; Rousset, Perrine; Martin-Rosique, Rebeca; Bermudez-Humaran, Luis; Leroux, Jean Christophe; Murray, Joseph A; Smecuol, Edgardo; Bai, Julio C; Vergnolle, Nathalie; Langella, Philippe; Verdu, Elena F.

Am J Gastroenterol ; 109(5): 748-56, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24710505

12.

Evaluating the Effects of Chronic Oral Exposure to the Food Additive Silicon Dioxide on Oral Tolerance Induction and Food Sensitivities in Mice.

Lamas, Bruno; Martins Breyner, Natalia; Malaisé, Yann; Wulczynski, Mark; Galipeau, Heather J; Gaultier, Eric; Cartier, Christel; Verdu, Elena F; Houdeau, Eric.

Environ Health Perspect ; 132(2): 27007, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38380914

13.

The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues.

Pinier, Maud; Fuhrmann, Gregor; Galipeau, Heather J; Rivard, Nathalie; Murray, Joseph A; David, Chella S; Drasarova, Hana; Tuckova, Ludmila; Leroux, Jean-Christophe; Verdu, Elena F.

Gastroenterology ; 142(2): 316-25.e1-12, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22079593

14.

Differential induction of antimicrobial REGIII by the intestinal microbiota and Bifidobacterium breve NCC2950.

Natividad, Jane M M; Hayes, Christina L; Motta, Jean-Paul; Jury, Jennifer; Galipeau, Heather J; Philip, Vivek; Garcia-Rodenas, Clara L; Kiyama, Hiroshi; Bercik, Premysl; Verdu, Elena F.

Appl Environ Microbiol ; 79(24): 7745-54, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24096422

15.

Sensitization to gliadin induces moderate enteropathy and insulitis in nonobese diabetic-DQ8 mice.

Galipeau, Heather J; Rulli, Nestor E; Jury, Jennifer; Huang, Xianxi; Araya, Romina; Murray, Joseph A; David, Chella S; Chirdo, Fernando G; McCoy, Kathy D; Verdu, Elena F.

J Immunol ; 187(8): 4338-46, 2011 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-21911598

16.

Protection from inflammatory bowel disease.

Galipeau, Heather J; Verdu, Elena F.

Science ; 381(6663): 1153-1154, 2023 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-37708269

17.

Elucidating the role of microbes in celiac disease through gnotobiotic modeling.

Caminero, Alberto; Verdu, Elena F; Galipeau, Heather J.

Methods Cell Biol ; 179: 77-101, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37625882

18.

Gut microbiota modulates visceral sensitivity through calcitonin gene-related peptide (CGRP) production.

Pujo, Julien; De Palma, Giada; Lu, Jun; Galipeau, Heather J; Surette, Michael G; Collins, Stephen M; Bercik, Premysl.

Gut Microbes ; 15(1): 2188874, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-36939195

19.

The double-edged sword of gut bacteria in celiac disease and implications for therapeutic potential.

Galipeau, Heather J; Verdu, Elena F.

Mucosal Immunol ; 15(2): 235-243, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-35031683

20.

Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation.

Lamas, Bruno; Hernandez-Galan, Leticia; Galipeau, Heather J; Constante, Marco; Clarizio, Alexandra; Jury, Jennifer; Breyner, Natalia M; Caminero, Alberto; Rueda, Gaston; Hayes, Christina L; McCarville, Justin L; Bermudez Brito, Miriam; Planchais, Julien; Rolhion, Nathalie; Murray, Joseph A; Langella, Philippe; Loonen, Linda M P; Wells, Jerry M; Bercik, Premysl; Sokol, Harry; Verdu, Elena F.

Sci Transl Med ; 12(566)2020 10 21.

Artigo em Inglês | MEDLINE | ID: mdl-33087499

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The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells.

Non-Host Factors Influencing Onset and Severity of Celiac Disease.

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Biogeographic Variation and Functional Pathways of the Gut Microbiota in Celiac Disease.

Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis.

A Riddle, Wrapped in a Mystery, Inside an Enigma: Another Key to Wheat Sensitivity?

Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins.

Lifelong memory responses perpetuate humoral T_H2 immunity and anaphylaxis in food allergy.

Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity.

Intestinal microbiota modulates gluten-induced immunopathology in humanized mice.

Novel role of the serine protease inhibitor elafin in gluten-related disorders.

Evaluating the Effects of Chronic Oral Exposure to the Food Additive Silicon Dioxide on Oral Tolerance Induction and Food Sensitivities in Mice.

The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues.

Differential induction of antimicrobial REGIII by the intestinal microbiota and Bifidobacterium breve NCC2950.

Sensitization to gliadin induces moderate enteropathy and insulitis in nonobese diabetic-DQ8 mice.

Protection from inflammatory bowel disease.

Elucidating the role of microbes in celiac disease through gnotobiotic modeling.

Gut microbiota modulates visceral sensitivity through calcitonin gene-related peptide (CGRP) production.

The double-edged sword of gut bacteria in celiac disease and implications for therapeutic potential.

Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation.