Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex.

Papadopoulos, Dimitrios; Ha, Stefanie Anh; Fleischhauer, Daniel; Uhl, Leonie; Russell, Timothy J; Mikicic, Ivan; Schneider, Katharina; Brem, Annika; Valanju, Omkar Rajendra; Cossa, Giacomo; Gallant, Peter; Schuelein-Voelk, Christina; Maric, Hans Michael; Beli, Petra; Büchel, Gabriele; Vos, Seychelle M; Eilers, Martin.

Mol Cell ; 84(11): 2070-2086.e20, 2024 Jun 06.

Artigo em Inglês | MEDLINE | ID: mdl-38703770

2.

Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters.

Endres, Theresa; Solvie, Daniel; Heidelberger, Jan B; Andrioletti, Valentina; Baluapuri, Apoorva; Ade, Carsten P; Muhar, Matthias; Eilers, Ursula; Vos, Seychelle M; Cramer, Patrick; Zuber, Johannes; Beli, Petra; Popov, Nikita; Wolf, Elmar; Gallant, Peter; Eilers, Martin.

Mol Cell ; 81(4): 830-844.e13, 2021 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-33453168

3.

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation.

Baluapuri, Apoorva; Hofstetter, Julia; Dudvarski Stankovic, Nevenka; Endres, Theresa; Bhandare, Pranjali; Vos, Seychelle Monique; Adhikari, Bikash; Schwarz, Jessica Denise; Narain, Ashwin; Vogt, Markus; Wang, Shuang-Yan; Düster, Robert; Jung, Lisa Anna; Vanselow, Jens Thorsten; Wiegering, Armin; Geyer, Matthias; Maric, Hans Michael; Gallant, Peter; Walz, Susanne; Schlosser, Andreas; Cramer, Patrick; Eilers, Martin; Wolf, Elmar.

Mol Cell ; 74(4): 674-687.e11, 2019 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-30928206

4.

Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts.

Trifault, Barbara; Mamontova, Victoria; Cossa, Giacomo; Ganskih, Sabina; Wei, Yuanjie; Hofstetter, Julia; Bhandare, Pranjali; Baluapuri, Apoorva; Nieto, Blanca; Solvie, Daniel; Ade, Carsten P; Gallant, Peter; Wolf, Elmar; Larsen, Dorthe H; Munschauer, Mathias; Burger, Kaspar.

Nucleic Acids Res ; 52(6): 3050-3068, 2024 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-38224452

5.

PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters.

Gerlach, Jennifer M; Furrer, Michael; Gallant, Maria; Birkel, Dirk; Baluapuri, Apoorva; Wolf, Elmar; Gallant, Peter.

Proc Natl Acad Sci U S A ; 114(44): E9224-E9232, 2017 10 31.

Artigo em Inglês | MEDLINE | ID: mdl-29078288

6.

Max-independent functions of Myc in Drosophila melanogaster.

Steiger, Dominik; Furrer, Michael; Schwinkendorf, Daniela; Gallant, Peter.

Nat Genet ; 40(9): 1084-91, 2008 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-19165923

7.

snoRNAs are a novel class of biologically relevant Myc targets.

Herter, Eva K; Stauch, Maria; Gallant, Maria; Wolf, Elmar; Raabe, Thomas; Gallant, Peter.

BMC Biol ; 13: 25, 2015 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-25888729

8.

Spt5 interacts genetically with Myc and is limiting for brain tumor growth in Drosophila.

Hofstetter, Julia; Ogunleye, Ayoola; Kutschke, André; Buchholz, Lisa Marie; Wolf, Elmar; Raabe, Thomas; Gallant, Peter.

Life Sci Alliance ; 7(1)2024 01.

Artigo em Inglês | MEDLINE | ID: mdl-37935464

9.

PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma.

Gaballa, Abdallah; Gebhardt-Wolf, Anneli; Krenz, Bastian; Mattavelli, Greta; John, Mara; Cossa, Giacomo; Andreani, Silvia; Schülein-Völk, Christina; Montesinos, Francisco; Vidal, Raphael; Kastner, Carolin; Ade, Carsten P; Kneitz, Burkhard; Gasteiger, Georg; Gallant, Peter; Rosenfeldt, Mathias; Riedel, Angela; Eilers, Martin.

Nat Commun ; 15(1): 1446, 2024 Feb 16.

Artigo em Inglês | MEDLINE | ID: mdl-38365788

10.

Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth.

Furrer, Michael; Balbi, Mirjam; Albarca-Aguilera, Monica; Gallant, Maria; Herr, Winship; Gallant, Peter.

J Biol Chem ; 285(51): 39623-36, 2010 Dec 17.

Artigo em Inglês | MEDLINE | ID: mdl-20937797

11.

MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma.

Krenz, Bastian; Gebhardt-Wolf, Anneli; Ade, Carsten P; Gaballa, Abdallah; Roehrig, Florian; Vendelova, Emilia; Baluapuri, Apoorva; Eilers, Ursula; Gallant, Peter; D'Artista, Luana; Wiegering, Armin; Gasteiger, Georg; Rosenfeldt, Mathias T; Bauer, Stefan; Zender, Lars; Wolf, Elmar; Eilers, Martin.

Cancer Res ; 81(16): 4242-4256, 2021 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-34145038

12.

Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma.

Roeschert, Isabelle; Poon, Evon; Henssen, Anton G; Garcia, Heathcliff Dorado; Gatti, Marco; Giansanti, Celeste; Jamin, Yann; Ade, Carsten P; Gallant, Peter; Schülein-Völk, Christina; Beli, Petra; Richards, Mark; Rosenfeldt, Mathias; Altmeyer, Matthias; Anderson, John; Eggert, Angelika; Dobbelstein, Matthias; Bayliss, Richard; Chesler, Louis; Büchel, Gabriele; Eilers, Martin.

Nat Cancer ; 2(3): 312-326, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33768209

13.

Induction of apoptosis by Drosophila Myc.

Montero, Lilian; Müller, Nadine; Gallant, Peter.

Genesis ; 46(2): 104-11, 2008 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-18257071

14.

Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes.

Hulf, Toby; Bellosta, Paola; Furrer, Michael; Steiger, Dominik; Svensson, David; Barbour, Andrew; Gallant, Peter.

Mol Cell Biol ; 25(9): 3401-10, 2005 May.

Artigo em Inglês | MEDLINE | ID: mdl-15831447

15.

Getting started : an overview on raising and handling Drosophila.

Stocker, Hugo; Gallant, Peter.

Methods Mol Biol ; 420: 27-44, 2008.

Artigo em Inglês | MEDLINE | ID: mdl-18641939

16.

Myc, cell competition, and compensatory proliferation.

Gallant, Peter.

Cancer Res ; 65(15): 6485-7, 2005 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-16061622

17.

Drosophila mbm is a nucleolar myc and casein kinase 2 target required for ribosome biogenesis and cell growth of central brain neuroblasts.

Hovhanyan, Anna; Herter, Eva K; Pfannstiel, Jens; Gallant, Peter; Raabe, Thomas.

Mol Cell Biol ; 34(10): 1878-91, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24615015

18.

Myc function in Drosophila.

Gallant, Peter.

Cold Spring Harb Perspect Med ; 3(10): a014324, 2013 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-24086064

19.

Flower dooms cells to death.

Gallant, Peter.

Dev Cell ; 18(6): 882-3, 2010 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-20627071

20.

Myc Function in Drosophila.

Bellosta, Paola; Gallant, Peter.

Genes Cancer ; 1(6): 542-546, 2010 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-21072325

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The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex.

Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters.

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation.

Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts.

PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters.

Max-independent functions of Myc in Drosophila melanogaster.

snoRNAs are a novel class of biologically relevant Myc targets.

Spt5 interacts genetically with Myc and is limiting for brain tumor growth in Drosophila.

PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma.

Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth.

MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma.

Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma.

Induction of apoptosis by Drosophila Myc.

Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes.

Getting started : an overview on raising and handling Drosophila.

Myc, cell competition, and compensatory proliferation.

Drosophila mbm is a nucleolar myc and casein kinase 2 target required for ribosome biogenesis and cell growth of central brain neuroblasts.

Myc function in Drosophila.

Flower dooms cells to death.

Myc Function in Drosophila.