Detalhe da pesquisa
1.
Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.
Cell
; 172(5): 952-965.e18, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29474921
2.
Polyphosphate: A Conserved Modifier of Amyloidogenic Processes.
Mol Cell
; 63(5): 768-80, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27570072
3.
Mitochondrial calcium uniporter deficiency in dentate granule cells remodels neuronal metabolism and impairs reversal learning.
J Neurochem
; 2023 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37415312
4.
mTOR Attenuation with Rapamycin Reverses Neurovascular Uncoupling and Memory Deficits in Mice Modeling Alzheimer's Disease.
J Neurosci
; 41(19): 4305-4320, 2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33888602
5.
In Vivo Generation of Lung and Thyroid Tissues from Embryonic Stem Cells Using Blastocyst Complementation.
Am J Respir Crit Care Med
; 203(4): 471-483, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877203
6.
Mechanisms of Vascular Aging.
Circ Res
; 123(7): 849-867, 2018 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355080
7.
Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
Am J Physiol Heart Circ Physiol
; 314(4): H693-H703, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29351469
8.
A Perfect sTORm: The Role of the Mammalian Target of Rapamycin (mTOR) in Cerebrovascular Dysfunction of Alzheimer's Disease: A Mini-Review.
Gerontology
; 64(3): 205-211, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29320772
9.
Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease.
Biochim Biophys Acta
; 1862(5): 992-1007, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26639036
10.
Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in Aß internalization.
Hippocampus
; 26(2): 194-210, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26235241
11.
Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease.
Hippocampus
; 24(3): 257-69, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24132937
12.
Neurovascular coupling impairment as a mechanism for cognitive deficits in COVID-19.
Brain Commun
; 6(2): fcae080, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38495306
13.
Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.
J Neurochem
; 124(6): 880-93, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23121022
14.
Rapamycin restores peripheral blood flow in aged mice and in mouse models of atherosclerosis and Alzheimer's disease.
Geroscience
; 45(3): 1987-1996, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37052770
15.
Effect of Nrf2 loss on senescence and cognition of tau-based P301S mice.
Geroscience
; 45(3): 1451-1469, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976489
16.
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy.
Nat Commun
; 14(1): 2367, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37185259
17.
Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study.
PLoS One
; 18(8): e0289508, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37535668
18.
Age-related impairment of metabovascular coupling during cortical spreading depolarizations.
Am J Physiol Heart Circ Physiol
; 313(6): H1209-H1212, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28842440
19.
Development of a high-throughput screen targeting caspase-8-mediated cleavage of the amyloid precursor protein.
Anal Biochem
; 421(2): 467-76, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22178911
20.
Editorial: Comparison of antibody and T cell responses elicited by BBIBP-CorV (Sinopharm) and BNT162b2 (Pfizer-BioNTech) vaccines against SARS-CoV-2 in healthy adult humans.
Geroscience
; 44(1): 57-61, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935099