Detalhe da pesquisa
1.
Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPß in Microglia.
Cell
; 182(5): 1156-1169.e12, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32795415
2.
LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity.
Nature
; 611(7934): 148-154, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36171287
3.
Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease.
J Med Chem
; 67(5): 3287-3306, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38431835
4.
TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice.
Elife
; 122023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37555828
5.
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Nat Aging
; 2(9): 837-850, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118504
6.
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by ß-amyloid pathology.
Neuron
; 109(8): 1283-1301.e6, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675684
7.
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
J Exp Med
; 218(4)2021 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620419
8.
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Cell Rep
; 28(8): 2111-2123.e6, 2019 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31433986
9.
Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer.
Front Immunol
; 10: 2019, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31552020
10.
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Neuron
; 100(6): 1322-1336.e7, 2018 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30392797
11.
IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice.
PLoS One
; 12(1): e0170639, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28125663
12.
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Sci Transl Med
; 9(403)2017 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28814543
13.
Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/ßKlotho Complex.
EBioMedicine
; 2(7): 730-43, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26288846
14.
CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and ß1-integrin signaling pathways.
J Invest Dermatol
; 133(1): 221-9, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22832488
15.
Antibody-mediated activation of FGFR1 induces FGF23 production and hypophosphatemia.
PLoS One
; 8(2): e57322, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23451204