Detalhe da pesquisa
1.
Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy.
Bioorg Chem
; 119: 105549, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34929517
2.
AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model.
Molecules
; 27(19)2022 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36235254
3.
Identification and structure-activity relationship studies of small molecule inhibitors of the human cathepsin D.
Bioorg Med Chem
; 29: 115879, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33271453
4.
Water-Promoted Regiospecific Azidolysis and Copper-Catalyzed Azide-Alkyne Cycloaddition: One-Pot Synthesis of 3-Hydroxy-1-alkyl-3-[(4-aryl/alkyl-1H-1,2,3-triazol-1-yl)methyl]indolin-2-ones.
J Org Chem
; 81(20): 9757-9764, 2016 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27657181
5.
High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes.
J Med Chem
; 64(15): 11379-11394, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34337941