Low-Power Failure Detection for Environmental Monitoring Based on IoT.

Many environmental monitoring applications that are based on the Internet of Things (IoT) require robust and available systems. These systems must be able to tolerate the hardware or software failure of nodes and communication failure between nodes. However, node failure is inevitable due to environmental and human factors, and battery depletion in particular is a major contributor to node failure. The existing failure detection algorithms seldom consider the problem of node battery consumption. In order to rectify this, we propose a low-power failure detector (LP-FD) that can provide an acceptable failure detection service and can save on the battery consumption of nodes. From simulation experiments, results show that the LP-FD can provide better detection speed, accuracy, overhead and battery consumption than other failure detection algorithms.

[Splenic tyrosine kinase promotes pulmonary angiogenesis in rats with hepatopulmonary syndrome].

The present paper was aimed to study the role of spleen tyrosine kinase (Syk) in angiogenesis in hepatopulmonary syndrome (HPS) and the underlying mechanism. Sprague Dawley (SD) rats were randomly divided into three groups: sham operation group (sham group), common bile duct ligation (CBDL) 5-week group (5W group) and R788 intervention group (R788 group). HPS model was established by CBDL. Rats in R788 group were intraperitoneally injected with R788 (20 mg/kg) once daily to week 5 after CBDL operation. The protein expression levels and distribution of Syk, p-Erk1/2, and p-Akt in lung tissue were detected by Western blot and immunohistochemistry. Immunofluorescence staining was used to observe the location of Syk expression and the number of angiogenesis in lung tissue. The results showed that, compared with sham group, 5W group exhibited up-regulated protein expression level of Syk, increased phosphorylation levels of Erk1/2 and Akt, and increased number of pulmonary microvessels. Compared with 5W group, R788 group exhibited down-regulated protein expression level of Syk, decreased phosphorylation levels of Erk1/2 and Akt, and decreased number of pulmonary microvessels. These results suggest that Syk may promote pulmonary angiogenesis in HPS model rats by activating downstream Erk1/2 and Akt signaling pathways, which provides a theoretical basis and potential drug therapeutic targets for the clinical treatment of HPS.