[Training of health care workers on the Chronic Care Model]. / Intervención dirigida al equipo de salud para fortalecer la implementación del Modelo de Cuidados Crónicos.

BACKGROUND: The Chronic Care Model promotes the link between informed, activated patients with proactive and prepared health care teams. AIM: To evaluate the effect of an intervention aimed at strengthening the implementation of the Chronic Care Model in the care provided by health teams to users with chronic diseases. MATERIAL AND METHODS: Quasi-experiment study. Four health centers were randomly selected, divided into intervention and control groups, with 86 participants who met the selection criteria and agreed to participate in the study. A blended learning training program, lasting six months, was applied in intervened centers to incorporate the elements of the Chronic Care Model. The results were assessed using the questionnaire "Assessment of chronic illness care, internal client version 3.5" adapted to Chilean Spanish. RESULTS: A significant post-intervention improvement in the global score of attention evaluation was observed in the group that received the intervention, changing from basic su- pport to reasonably good support. Also, specific improvements were seen in five sections of the attention assessment. CONCLUSIONS: This intervention improved the evaluation of chronic disease care in the intervention group.

How effective are mobile apps in managing people with type 2 diabetes mellitus? A systematic literature review protocol.

INTRODUCTION: The rise of new technologies in the field of health is yielding promising results. In certain chronic conditions such as type 2 diabetes mellitus, which ranks among the top five causes of global mortality, it could be useful in supporting patient management. MATERIALS AND METHODS: A systematic review will be conducted on scientific publications from the last 5 years (January 2019 to October 2023) to describe the effect of mobile app usage on glycated hemoglobin for the management of adult patients with type 2 diabetes mellitus who participated in randomized controlled clinical trials. The search will be carried out in the databases of MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), CENTRAL, WoS, Scopus, Epistemonikos, and LILACS. The search strategy will be constructed using both controlled and natural language. Additionally, the Cochrane filter will be applied to identify randomized controlled trials. The review will include scientific articles reporting studies that present results from randomized controlled trials, with texts in Spanish, English, or French, utilizing mobile applications for the management of adult individuals (over 18 years) with type 2 diabetes mellitus, and whose outcomes report the effects on glycated hemoglobin. The Cochrane Risk of Bias Tool will be used to assess the quality of the studies, and the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology will be implemented to evaluate the certainty of the evidence. RESULTS: The analysis will be conducted by observing the value of the glycated hemoglobin levels of the participants. Given that this data is a quantitative and continuous value, it facilitates the identification of the effects of the mobile applications used for the management of type 2 diabetes mellitus (T2DM) in adults. Furthermore, if sufficient data are available, a meta-analysis will be conducted using IBM-SPSS. The effect of the intervention will be estimated by the mean difference. All point estimates will be accompanied by 95% confidence intervals. A random effects model will be used. The heterogeneity of the results will be assessed using Cochrane's Q and I2 statistics. DISCUSSION: Considering that the quality of content and functionality of certain applications in the healthcare field is highly variable, it is necessary to evaluate the scientific evidence reported on the effect of the use of this type of technology in people with T2DM.

La teoría de las transiciones como paradigma de apoyo al automanejo en personas con condiciones crónicas / Transitions theory as a paradigm for supporting self-management in people with chronic conditions / A teoria das transições como paradigma para apoiar a autogestão em pessoas com condições crónicas

Resumen Introducción: La experiencia de vivir con una enfermedad crónica no es una tarea sencilla, se requiere de herramientas que permitan aumentar el grado de conciencia para enfrentar las necesidades y superar desafíos sobre el estado de salud y enfermedad. En los últimos años, se ha instaurado el apoyo al automanejo, con la finalidad de potenciar las habilidades en personas con este tipo de afecciones. Resulta trascendental considerar como desde enfermería se puede contribuir al logro de aquello. El objetivo del presente ensayo es reflexionar acerca de la teoría de las transiciones de Meléis como paradigma de apoyo al automanejo en personas con condiciones crónicas. Desarrollo: La teoría de las transiciones de Meléis establece que las personas están en constante cambio, tal como ocurre en el proceso de transición de salud-enfermedad. Recibir el diagnóstico de una enfermedad crónica, conlleva una serie de procesos complejos para la persona, debido a la multiplicidad de variables que ello implica. La teoría de Meléis entrega lineamientos para orientar a la persona profesional de enfermería sobre elementos claves e interrelacionados, como la concepción previa de la naturaleza de la transición y sus condiciones, lo que servirá para la planificación de modalidades de intervención congruentes con las experiencias de la persona y su evaluación en el transcurso del proceso de salud y enfermedad. Conclusión: El paradigma ofrecido por Meléis puede ser considerado un enfoque clave para emprender el proceso de cuidado de enfermería tendiente a apoyar a las personas con enfermedad crónica en el logro del automanejo.

Abstract Introduction: The experience of living with a chronic disease is not a simple task, since it requires tools that allow increasing the degree of awareness to face the needs and overcome challenges about the state of health and disease. In recent years, support for self-management has been established, with the aim of enhancing the skills of people with this type of condition. It is important to consider how the nursing discipline can contribute to achieve this. The aim of this paper is to reflect on Meléis' theory of transitions as a paradigm to support self-management in people with chronic conditions. Development: Meléis' theory of transitions establishes that people are in constant change, as occurs in the health-illness transition process. Receiving the diagnosis of a chronic disease involves a series of complex processes for the person, due to the multiplicity of variables involved. Meléis' theory provides guidelines to orient the nursing professional on key and interrelated elements, such as the previous conception of the nature of the transition and its conditions, which will serve for the planning of intervention modalities congruent with the person's experiences and their evaluation in the course of the health and disease process. Conclusion: The paradigm offered by Meléis can be considered a key approach to undertake the nursing care process aimed at supporting people with chronic illness in achieving self-management.

Resumo Introdução: A experiênca de viver com uma doença crônica não é uma tarefa simple, pois requer ferramentas que permitam aumentar o nível de consciência para enfrentar as necessidades e superar desafios relativos ao estado de saúde e doença. Nos últimos anos, foi estabelecido o apoio à autogestão, com o objetivo de melhorar as habilidades das pessoas com este tipo de condições. É transcendental considerar como a disciplina de Enfermagem pode contribuir para isso. O objetivo deste ensaio é refletir sobre a teoria das transições de Meleis como paradigma de apoio à autogestão em pessoas com condições crônicas. Desenvolvimento: A teoria das transições de Meléis estabelece que as pessoas estão em constante mudança, como acontece no processo de transição saúde-doença. Receber o diagnóstico de uma doença crónica implica uma série de processos complexos para a pessoa, devido à multiplicidade de variáveis envolvidas. A teoria de Meléis fornece directrizes para orientar o profissional de enfermagem sobre elementos-chave e inter-relacionados, como a conceção prévia da natureza da transição e das suas condições, que servirão para o planeamento de modalidades de intervenção congruentes com as experiências da pessoa e a sua avaliação no decurso do processo saúde-doença. Conclusão: O paradigma oferecido por Meleis pode ser considerado uma abordagem chave para empreender o processo de cuidado de enfermagem que visa apoiar as pessoas com doenças crônicas no alcance do autogerenciamento.

Analysis of the protective capacity of three Streptococcus suis proteins induced under divalent-cation-limited conditions.

Streptococcus suis is a gram-positive pathogen that causes serious diseases in pigs and, in some cases, humans. Three genes of the virulent S. suis 89/1591 strain, encoding putative divalent-cation-binding lipoproteins, were isolated based on information obtained from the draft annotation files of this organism's genome. The products of these genes, which are inducible by divalent-cation deprivation, were subsequently purified, and their immunogenic and protective abilities were analyzed. All three proteins (SsuiDRAFT 0103, SsuiDRAFT 0174, and SsuiDRAFT 1237) were found to be immunogenic, but only one of them (SsuiDRAFT 0103) induced a significant protective response (87.5%, P = 0.01) against the same S. suis strain. Furthermore, the S. suis ssuiDRAFT 1240 gene (adcR), which encodes a predicted regulator of Zn2+ and/or Mn2+ uptake in streptococci, was cloned, and its protein product was purified. Electrophoretic mobility shift assays with purified S. suis AdcR protein showed experimentally, for the first time, that the AdcR DNA-binding sequence corresponds to the TTAACNRGTTAA motif. In addition, a requirement for either Zn2+ or Mn2+, but not Fe2+, to establish in vitro binding of AdcR to its target sequence and the ability of AdcR to bind the ssuiDRAFT 0103 and ssuiDRAFT 1237 gene promoters but not the promoter of the ssuiDRAFT 0174 gene were demonstrated. Taken together, these data suggest that SsuiDRAFT 0103 is a good candidate for vaccines against S. suis and support preliminary results indicating that bacterial envelope proteins involved in the uptake of divalent cations other than iron may be useful for protective purposes.

El Modelo Transteórico y la Teoría del Automanejo Individual y Familiar como paradigma para comprender el cambio de comportamiento y el automanejo en personas con enfermedades crónicas / The Transtheoretical Model and the Individual and Family Self-Management Theory as a paradigm to understand behavior change and self-management in people with chronic diseases

INTRODUCCIÓN: El automanejo y el cambio de conducta siguen siendo retos para quienes padecen enfermedades crónicas. Para su abordaje existen modelos y estrategias que orientan a alcanzar mejores resultados en salud. OBJETIVO: Analizar la Teoría del Automanejo Individual y Familiar junto con el Modelo Transteórico como paradigmas para comprender los desafíos e identificar factores involucrados en el cambio conductual y el automanejo de personas con enfermedades crónicas. DESARROLLO: El Modelo Transteórico comprende cinco etapas que explican el proceso cíclico de cambio. Por otro lado, la Teoría del Automanejo Individual y Familiar se distingue por tres dimensiones: contexto, proceso y resultados. Al interrelacionar ambos modelos, se observa que el contexto dado por la Teoría del Automanejo Individual y Familiar puede determinar la etapa del cambio. Los procesos, como la autoeficacia, la facilitación social o la autorregulación, son implementados de formas distintas según la etapa del cambio en la que la persona se encuentre. CONCLUSIÓN: La integración de ambos modelos potencia la comprensión acerca del cambio de conducta en personas con enfermedades crónicas. Esta articulación favorece enfoques más personalizados, lo que permitiría que los profesionales de enfermería reconocer la etapa de cambio en la que se encuentra la persona y, con base en la Teoría del Automanejo, atender las necesidades del individuo y familia, propiciando un cuidado integral.

INTRODUCTION: Self-management and behavioral change continue to be challenges for those suffering from chronic diseases. There are models and strategies for approaching them that aim to achieve better health outcomes. OBJECTIVE: Analyze the Individual and Family Self-Management Theory together with the Transtheoretical Model as paradigms to understand the challenges and identify factors involved in behavioral change and self-management of people with chronic diseases. DEVELOPMENT: The Transtheoretical Model comprises five stages that explain the cyclical process of change. On the other hand, the Individual and Family Self-Management Theory is distinguished by three dimensions: context, process and outcomes. By interrelating both models, it is observed that the context given by the Individual and Family Self-Management Theory can determine the stage of change. Processes, such as self-efficacy, social facilitation or self-regulation, are implemented in different ways depending on the stage of change the person is in. Finally, outcomes, such as self-management, emerge from the effective joint application of both models. CONCLUSION: The integration of both models enhances the understanding of behavior change in people with chronic diseases. This articulation favors more personalized approaches, which would allow nursing professionals to recognize the stage of change in which the person is and, based on the Self-Management Theory, address the needs of the individual and family, promoting comprehensive care.

Transitando desde las fases de cambio de comportamiento hacia el automanejo de personas con condiciones crónicas / Transiting from phases of behavior change to the self-management of people with chronic conditions

Introducción: A nivel mundial existe una constante preocupación debido a que cada día proliferan más personas con enfermedades crónicas. Para su abordaje, se han propuesto una serie de medidas que enfatizan el rol preponderante que tiene la persona en el logro del automanejo de su salud y enfermedad. El objetivo de este trabajo fue reflexionar acerca de elementos que favorecen el avance desde las etapas de cambio hacia el automanejo de personas con condiciones crónicas. Desarrollo: Para lograr el automanejo, resulta trascendental considerar en la atención a la persona con enfermedades crónicas, entre otros aspectos, el proceso de cambio de comportamiento y el grado de autoeficacia percibida. Asimismo, el personal profesional de la atención primaria de salud y enfermería requieren desarrollar habilidades específicas y de alta idoneidad para una atención integral, oportuna y continuada. Todos estos aspectos se interrelacionan para converger juntos en un plan de atención de salud colaborativo, consensuado y centrado en la persona. Conclusión: Para favorecer el avance del automanejo existen elementos tanto de la persona con enfermedad crónica como de la profesional que se articulan. Entre estas personas se dan relaciones de bidireccionalidad, que han de ser vistas como un proceso funcional continuo y no como elementos discretos en el cuidado en salud.

Introdução: Em todo o mundo existe uma preocupação constante, pois a cada dia proliferam mais pessoas com doenças crônicas. Para sua abordagem, foi proposta uma série de medidas que enfatizam o papel preponderante que a pessoa tem na realização do autogerenciamento de sua saúde e doença. O objetivo deste trabalho foi refletir sobre elementos que favorecem a passagem das etapas de mudança para a autogestão de pessoas com condições crônicas. Desenvolvimento: A fim de alcançar a autogestão, é crucial considerar, entre outros aspectos, o processo de mudança de comportamento e o grau de auto-eficácia percebido no cuidado da pessoa cronicamente doente. Do mesmo modo, os profissionais de cuidados de saúde primários e de enfermagem precisam desenvolver competências específicas e altamente qualificadas para cuidados abrangentes, atempados e contínuos. Todos estes aspectos se inter-relacionam para convergir em um plano de cuidados de saúde colaborativo, consensual e centrado na pessoa. Conclusão: Para favorecer o avanço da autogestão, há elementos tanto da pessoa quanto do profissional que se articulam, existindo relações bidirecionais entre eles, que devem ser vistos como um processo funcional contínuo e não como elementos discretos no cuidado à saúde.

Introduction: There is worldwide constant concern because of the increasing number of people with chronic diseases every day. When it comes to approaching this situation, a series of measures have been proposed to emphasize the preponderant role that the people have has in achieving the self-management of their health and disease. The objective of this work was to reflect on the elements that favor progress from the stages of change towards self-management in people with chronic conditions. Development: To achieve self-management, it is essential to consider - among other aspects - the process of behavioral change and the degree of perceived self-efficacy in the care of chronically ill people. Likewise, primary healthcare and nursing professionals need to develop specific and highly suitable skills for comprehensive, timely, and continuous care. All these aspects interrelate to converge together in a collaborative, consensual, and person-centered healthcare plan. Conclusion: To favor the advancement of self-management, there are elements that both the person and the professional need to articulate, for instance, the existing bidirectional relationships between them must be seen as a continuous functional process and not as discrete elements in healthcare.

Fortalecimiento del recurso humano para la atención de personas con enfermedades crónicas / Strengthening Human Resources for Providing Care to People with Chronic Diseases

Introducción: Las enfermedades crónicas implican un reto sanitario e intersectorial. Por ello, los prestadores requieren adquirir competencias específicas según estándares nacionales e internacionales para implantar una atención primaria de salud que provea acceso y cobertura universal. Objetivo: Reflexionar sobre elementos relevantes vinculados a las competencias de los proveedores de salud para la atención de personas con condiciones crónicas, en el contexto de la atención primaria de salud. Métodos: Se discuten estrategias, la implementación del Modelo de Cuidados Crónicos y la adquisición de competencias, analizando aspectos de la formación profesional, el aseguramiento de la educación continua y la disposición de los proveedores para estar a la vanguardia de los cuidados. Conclusiones: Para proveer una atención integral a personas con enfermedades crónicas es necesario el fortalecimiento del capital humano y la instalación de relaciones coproductivas entre el equipo multidisciplinario. Además, es fundamental que los equipos conozcan e incorporen estrategias con demostración de eficacia a nivel internacional, entre ellos se encuentra el Modelo de Cuidados Crónicos, cuya implementación ha sido lenta y con desarrollo parcial(AU)

Introduction: Chronic diseases represent a health and intersectoral challenge. Therefore, providers need to acquire specific competences according to national and international standards, in order to implement primary healthcare providing universal access and coverage. Objective: To reflect on the relevant elements related to the competences of healthcare providers for the care of people with chronic conditions in the context of primary healthcare. Methods: Strategies are discussed, together with the implementation of the chronic care model and the acquisition of competences, analyzing aspects of professional training, the assurance of continuing education and the willingness of providers to be at the forefront of care. Conclusions: In order to provide comprehensive care to people with chronic diseases, it is necessary to strengthen human capital and create coproductive relationships among the multidisciplinary team. In addition, it is essential that the teams be aware of and incorporate strategies that have been shown to be effective at the international level, including the chronic care model, whose implementation has been slow and only partially developed(AU)

Intervención dirigida al equipo de salud para fortalecer la implementación del Modelo de Cuidados Crónicos / Training of health care workers on the Chronic Care Model

BACKGROUND: The Chronic Care Model promotes the link between informed, activated patients with proactive and prepared health care teams. AIM: To evaluate the effect of an intervention aimed at strengthening the implementation of the Chronic Care Model in the care provided by health teams to users with chronic diseases. MATERIAL AND METHODS: Quasi-experiment study. Four health centers were randomly selected, divided into intervention and control groups, with 86 participants who met the selection criteria and agreed to participate in the study. A blended learning training program, lasting six months, was applied in intervened centers to incorporate the elements of the Chronic Care Model. The results were assessed using the questionnaire "Assessment of chronic illness care, internal client version 3.5" adapted to Chilean Spanish. RESULTS: A significant post-intervention improvement in the global score of attention evaluation was observed in the group that received the intervention, changing from basic su- pport to reasonably good support. Also, specific improvements were seen in five sections of the attention assessment. CONCLUSIONS: This intervention improved the evaluation of chronic disease care in the intervention group.

Trabajo en equipo y calidad de la atención en salud

RESUMEN Todas las organizaciones aspiran a alcanzar resultados funcionales e integrales para dar respuesta a las necesidades del medio interno y externo en el que se encuentran inmersas. La organización sanitaria no ha sido la excepción, por lo que proveer una atención con altos estándares de calidad se ha transformado en una prioridad a nivel mundial. En este sentido, se precisa poner en práctica una serie de elementos que confluyan funcionalmente para avanzar hacia la calidad de la atención en salud, en donde el trabajo en equipo, sus integrantes, el compromiso y la confianza entre las personas son claves para el logro de esta meta, especialmente para enfermería. El objetivo de este trabajo es describir la importancia del trabajo en equipo para la calidad de la atención en salud.

ABSTRACT All organizations aspire to achieve functional and comprehensive results in order to meet the needs of the internal and external environment in which they are immersed. The healthcare organization has been no exception, and providing high quality care has become a worldwide priority. In this sense, it is necessary to put into practice a series of elements that functionally converge to move towards the quality of health care, where teamwork, team members, commitment and trust between people are keys to achieving this goal, especially for nursing. The objective of this work is to describe the importance of teamwork for the quality of health care.

RESUMO Todas as organizações aspiram a resultados funcionais e abrangentes para responder às necessidades do ambiente interno e externo em que estão inseridas. A organização de saúde não tem sido exceção, portanto, prestar cuidados com elevados padrões de qualidade tornou-se uma prioridade em todo o mundo. Nesse sentido, é necessário colocar em prática uma série de elementos que convergem funcionalmente para caminhar rumo à qualidade da assistência à saúde, onde o trabalho em equipe, seus integrantes, o compromisso e a confiança entre as pessoas são fundamentais para o alcance desse objetivo, especialmente para enfermagem. O objetivo deste documento é descrever a importância do trabalho de equipa para a qualidade dos cuidados de saúde.

Generación, difusión y transferencia del conocimiento de enfermería a la práctica del cuidado / Generation, diffusion and transfer of nursing care knowledge into practice

El objetivo de este artículo es analizar y reflexionar sobre los aspectos relacionados con la generación, difusión y transferencia del conocimiento de enfermería a la práctica del cuidado. La generación del conocimiento de enfermería ha evolucionado gracias al desarrollo de la investigación científica, la cual ha producido conocimiento para dar respuestas a las necesidades de la profesión y de la sociedad, la difusión del mismo es imprescindible para que se produzca la transferencia de este conocimiento a la práctica de enfermería; sin embargo existen limitaciones y problemas en estas etapas del proceso que deben ser superados para lograr que este conocimiento permita ser contrastado con los cuidados proporcionados a las personas, familias y comunidades de la sociedad humana.

The aim of this paper is to analyze and meditate about the aspects related to the generation, dissemination and knowledge transfer to nursing care practice. The nursing knowledge generation has evolved thanks to the scientific research development, which has produced knowledge to respond to the profession and society requirements. Knowledge dissemination is essential to produce the transfer of this knowledge to nursing practice; however there are limitations and problems in these stages of the process that must be overcome to make this knowledge allowed to be contrasted with the care provided to individuals, families and communities of human society.

The cation-uptake regulators AdcR and Fur are necessary for full virulence of Streptococcus suis.

In streptococci, the pleiotropic regulators AdcR and Fur control the transport of, zinc and iron, respectively, which are essential components of many proteins. In this work, DeltaadcR, Deltafur, and DeltaadcR Deltafur mutants of Streptococcus suis, a serious pathogen in pigs and humans, were assayed in a mouse model to determine their involvement in the virulence of this bacterium. The results showed, for the first time, that the virulence of S. suis mutants carrying an inactivation of adcR, fur, or both genes is significantly attenuated compared to the wild-type parent strain. Furthermore, all mutants were found to be more sensitive to oxidative stress. Our data provide evidence that the adcR and fur genes play important roles in the oxidative stress response of S. suis as well as in the full virulence of this bacterium.

Protective capacities of cell surface-associated proteins of Streptococcus suis mutants deficient in divalent cation-uptake regulators.

Many cell surface-associated, divalent cation-regulated proteins are immunogenic, and some of them confer protection against the bacterial species from which they are derived. In this work, two Streptococcus suis divalent cation uptake regulator genes controlling zinc/manganese and iron uptake (adcR and fur, respectively) were inactivated in order to study the protective capacities of their cell surface-associated proteins. The results obtained showed overexpression of a set of immunogenic proteins (including members of the pneumococcal histidine triad family previously reported to confer protection against streptococcal pathogens) in S. suis adcR mutant cell surface extracts. Likewise, genes encoding zinc transporters, putative virulence factors and a ribosomal protein paralogue related to zinc starvation appeared to be derepressed in this mutant strain. Moreover, protection assays in mice showed that although neither adcR- nor fur-regulated cell surface-associated proteins were sufficient to confer protection in mice, the combination of both adcR- and fur-regulated cell surface-associated proteins is able to confer significant protection (50 %, P=0.038) against a challenge to mice vaccinated with them.