Detalhe da pesquisa
1.
Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation.
Am J Hum Genet
; 110(10): 1769-1786, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37729906
2.
Shifting landscapes of human MTHFR missense-variant effects.
Am J Hum Genet
; 108(7): 1283-1300, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34214447
3.
The geometric influence on the Cys2His2 zinc finger domain and functional plasticity.
Nucleic Acids Res
; 48(11): 6382-6402, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32383734
4.
Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB.
Proc Natl Acad Sci U S A
; 115(7): 1505-1510, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378946
5.
Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads.
Annu Rev Pharmacol Toxicol
; 57: 39-60, 2017 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27618737
6.
Rapid and accurate structure-based therapeutic peptide design using GPU accelerated thermodynamic integration.
Proteins
; 87(3): 236-244, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520126
7.
A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity.
Nucleic Acids Res
; 43(19): 9147-57, 2015 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26384429
8.
Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation.
bioRxiv
; 2023 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798224
9.
Dawn of a New Era for Membrane Protein Design.
Biodes Res
; 2022: 9791435, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850134
10.
Interplay of self-association and conformational flexibility in regulating protein function.
Philos Trans R Soc Lond B Biol Sci
; 373(1749)2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735742
11.
A computational approach for designing D-proteins with non-canonical amino acid optimised binding affinity.
PLoS One
; 12(11): e0187524, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29108013
12.
Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding.
Genome Biol
; 18(1): 167, 2017 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877740
13.
C2H2 zinc finger proteins greatly expand the human regulatory lexicon.
Nat Biotechnol
; 33(5): 555-62, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25690854
14.
A comprehensive model for the recognition of human telomeres by TRF1.
J Mol Biol
; 425(16): 2910-21, 2013 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23702294