Detalhe da pesquisa
1.
Novel oxazolidinone calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraine.
Bioorg Med Chem Lett
; 25(21): 4777-4781, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26231160
2.
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses.
Bioorg Med Chem Lett
; 24(3): 917-22, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24412110
3.
CRTH2 antagonist MK-7246: a synthetic evolution from discovery through development.
J Org Chem
; 77(5): 2299-309, 2012 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22335767
4.
Acute injection of ASP in the third ventricle inhibits food intake and locomotor activity in rats.
Am J Physiol Endocrinol Metab
; 301(1): E232-41, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21540449
5.
Evaluation of chylomicron effect on ASP production in 3T3-L1 adipocytes.
Acta Biochim Biophys Sin (Shanghai)
; 43(2): 154-9, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21266544
6.
Hormone and pharmaceutical regulation of ASP production in 3T3-L1 adipocytes.
J Cell Biochem
; 109(5): 896-905, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20069551
7.
Scalable synthesis of a prostaglandin EP4 receptor antagonist.
J Org Chem
; 75(12): 4078-85, 2010 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20469914
8.
A practical synthesis of 5-lipoxygenase inhibitor MK-0633.
J Org Chem
; 75(12): 4154-60, 2010 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20486715
9.
Practical synthesis of a potent bradykinin B(1) antagonist via enantioselective hydrogenation of a pyridyl N-acyl enamide.
J Org Chem
; 74(12): 4547-53, 2009 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19456171
10.
A practical enantioselective synthesis of odanacatib, a potent Cathepsin K inhibitor, via triflate displacement of an alpha-trifluoromethylbenzyl triflate.
J Org Chem
; 74(4): 1605-10, 2009 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19140725
11.
Remote electronic control in the regioselective reduction of succinimides: a practical, scalable synthesis of Ep4 antagonist MF-310.
J Org Chem
; 74(17): 6863-6, 2009 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19663395
12.
Hormonal and spatial regulation of nitric oxide synthases (NOS) (neuronal NOS, inducible NOS, and endothelial NOS) in the oviducts.
Endocrinology
; 147(12): 5600-10, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16935840
13.
Deficiency of C5L2 increases macrophage infiltration and alters adipose tissue function in mice.
PLoS One
; 8(4): e60795, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23630572
14.
C5L2 and C5aR interaction in adipocytes and macrophages: insights into adipoimmunology.
Cell Signal
; 25(4): 910-8, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23268185
15.
Differential chemoattractant response in adipocytes and macrophages to the action of acylation stimulating protein.
Eur J Cell Biol
; 92(2): 61-9, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23245988
16.
[Effect of metabolic drugs on the secretion of acylation stimulating protein in 3T3-L1 adipocytes].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
; 28(10): 1051-4, 2012 Oct.
Artigo
em Zh
| MEDLINE | ID: mdl-23046937
17.
Recombinant acylation stimulating protein administration to C3-/- mice increases insulin resistance via adipocyte inflammatory mechanisms.
PLoS One
; 7(10): e46883, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23056509
18.
A new effector of lipid metabolism: complement factor properdin.
Mol Immunol
; 51(1): 73-81, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22387270
19.
Practical synthesis of a renin inhibitor via a diastereoselective Dieckmann cyclization.
Org Lett
; 12(22): 5146-9, 2010 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20945851
20.
Recombinant C3adesArg/acylation stimulating protein (ASP) is highly bioactive: a critical evaluation of C5L2 binding and 3T3-L1 adipocyte activation.
Mol Immunol
; 46(16): 3207-17, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19767107