Detalhe da pesquisa
1.
Stem Leydig cells: Current research and future prospects of regenerative medicine of male reproductive health.
Semin Cell Dev Biol
; 121: 63-70, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001436
2.
Curcuminoid PBPD induces cuproptosis and endoplasmic reticulum stress in cervical cancer via the Notch1/RBP-J/NRF2/FDX1 pathway.
Mol Carcinog
; 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38801356
3.
Structure-activity relationship and mechanistic study of organotins as inhibitors of human, pig, and rat gonadal 3ß-hydroxysteroid dehydrogenases.
Toxicol Appl Pharmacol
; 486: 116942, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38692360
4.
Butorphanol inhibits androgen biosynthesis and metabolism in rat immature Leydig cells in vitro.
Can J Physiol Pharmacol
; 102(4): 270-280, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38258745
5.
Fecal transplantation of young mouse donors effectively improves enterotoxicity in elderly recipients exposed to triphenyltin.
Ecotoxicol Environ Saf
; 273: 116140, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417315
6.
Per- and polyfluoroalkyl substances inhibit human and rat 17ß-hydroxysteroid dehydrogenase 1: Quantitative structure-activity relationship and molecular docking analysis.
Ecotoxicol Environ Saf
; 273: 116173, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38452703
7.
Prenatal diethylhexylphthalate exposure disturbs adult Leydig cell function via epigenetic downregulation of METTL4 expression in male rats.
Ecotoxicol Environ Saf
; 277: 116391, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38678792
8.
The impact of tetrachlorobisphenol A exposure during puberty: Altered Leydig cell development and induced endoplasmic reticulum stress in male mice.
Ecotoxicol Environ Saf
; 270: 115895, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38159341
9.
Perfluorotetradecanoic acid exposure to adult male rats stimulates corticosterone biosynthesis but inhibits aldosterone production.
Environ Toxicol
; 39(5): 2610-2622, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38205621
10.
Halogenated bisphenol A derivatives potently inhibit human and rat 11ß-hydroxysteroid dehydrogenase 1: Structure-activity relationship and molecular docking.
Environ Toxicol
; 39(5): 2560-2571, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38189224
11.
Glucagon-like peptide-1 promotes Leydig cell regeneration from stem cells in rats.
Reproduction
; 165(1): 19-30, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36194433
12.
Curcumin analogues exert potent inhibition on human and rat gonadal 3ß-hydroxysteroid dehydrogenases as potential therapeutic agents: structure-activity relationship and in silico docking.
J Enzyme Inhib Med Chem
; 38(1): 2205052, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37184069
13.
Distinct inhibitory strength of bisphenol A analogues on human and rat 11ß-hydroxysteroid dehydrogenase 1: 3D quantitative structure-activity relationship and in silico molecular docking analysis.
Ecotoxicol Environ Saf
; 267: 115638, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37918333
14.
Citrinin inhibits the function of Leydig cells in male rats in prepuberty.
Ecotoxicol Environ Saf
; 252: 114568, 2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696728
15.
Benzene ring bisphenol A substitutes potently inhibit human, rat, and mouse gonadal 3ß-hydroxysteroid dehydrogenases: Structure-activity relationship and in silico docking analysis.
Ecotoxicol Environ Saf
; 264: 115461, 2023 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703809
16.
Direct inhibition of bisphenols on human and rat 11ß-hydroxysteroid dehydrogenase 2: Structure-activity relationship and docking analysis.
Ecotoxicol Environ Saf
; 254: 114715, 2023 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36871355
17.
Exposure to 4-nonylphenol compromises Leydig cell development in pubertal male mice.
Ecotoxicol Environ Saf
; 266: 115612, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37866035
18.
Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation.
Environ Toxicol
; 38(5): 997-1010, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715143
19.
Bisphenol S stimulates Leydig cell proliferation but inhibits differentiation in pubertal male rats through multiple mechanisms.
Environ Toxicol
; 38(10): 2361-2376, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37357847
20.
Bisphenol A Analogues Inhibit Human and Rat 11ß-Hydroxysteroid Dehydrogenase 1 Depending on Its Lipophilicity.
Molecules
; 28(13)2023 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446556