Detalhe da pesquisa
1.
Expression and function of the P2X7 receptor in human osteoblasts: The role of NFATc1 transcription factor.
J Cell Physiol
; 236(1): 641-652, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32583512
2.
The P2Y6 receptor signals through Gαq /Ca2+ /PKCα and Gα13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
J Cell Physiol
; 235(12): 9676-9690, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32420639
3.
The expression of the P2Y6 receptor is regulated at the transcriptional level by p53.
Biochem Biophys Res Commun
; 524(4): 798-802, 2020 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037085
4.
Reviewing the role of P2Y receptors in specific gastrointestinal cancers.
Purinergic Signal
; 15(4): 451-463, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31478181
5.
The G protein-coupled P2Y6 receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis.
Biochim Biophys Acta Mol Basis Dis
; 1864(5 Pt A): 1539-1551, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454075
6.
P2Y2 Receptor Functions in Cancer: A Perspective in the Context of Colorectal Cancer.
Adv Exp Med Biol
; 1051: 91-106, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28815512
7.
C/EBPß regulates P2X7 receptor expression in response to glucose challenge in intestinal epithelial cells.
Biochem Cell Biol
; 93(1): 38-46, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25403356
8.
Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists.
Bioorg Med Chem
; 23(17): 5764-73, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26233801
9.
The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.
Am J Physiol Gastrointest Liver Physiol
; 306(7): G594-605, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24525021
10.
P2Y2 receptor promotes intestinal microtubule stabilization and mucosal re-epithelization in experimental colitis.
J Cell Physiol
; 228(1): 99-109, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22553130
11.
Glucose transporter 2 expression is down regulated following P2X7 activation in enterocytes.
J Cell Physiol
; 228(1): 120-9, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566162
12.
Ligand-dependent intracellular trafficking of the G protein-coupled P2Y6 receptor.
Biochim Biophys Acta Mol Cell Res
; 1870(5): 119476, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059189
13.
UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety.
Bioorg Med Chem
; 20(18): 5483-95, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22901672
14.
Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells.
J Biol Chem
; 285(52): 40448-60, 2010 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20871093
15.
P2Y2 receptor transcription is increased by NF-kappa B and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells.
J Immunol
; 183(7): 4521-9, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19734210
16.
The expression of P2Y6 receptor promotes the quality of mucus in colitic mice.
FEBS J
; 288(18): 5459-5473, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33713543
17.
A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.
NAR Cancer
; 3(2): zcab019, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34316707
18.
Promoting MPhi transepithelial migration by stimulating the epithelial cell P2Y(2) receptor.
Eur J Immunol
; 39(10): 2895-905, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19634190
19.
Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-ß-phosphate scaffold.
Eur J Med Chem
; 184: 111754, 2019 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31610377
20.
Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-Pα,α-Dithiophosphate Analogues.
J Med Chem
; 61(9): 3939-3951, 2018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29681152