Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Centrosome function is critical during terminal erythroid differentiation.

Tátrai, Péter; Gergely, Fanni.

EMBO J ; 41(14): e108739, 2022 07 18.

Artigo em Inglês | MEDLINE | ID: mdl-35678476

2.

Centriolar satellites are acentriolar assemblies of centrosomal proteins.

Quarantotti, Valentina; Chen, Jia-Xuan; Tischer, Julia; Gonzalez Tejedo, Carmen; Papachristou, Evaggelia K; D'Santos, Clive S; Kilmartin, John V; Miller, Martin L; Gergely, Fanni.

EMBO J ; 38(14): e101082, 2019 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-31304626

3.

Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix.

Burgess, Selena G; Mukherjee, Manjeet; Sabir, Sarah; Joseph, Nimesh; Gutiérrez-Caballero, Cristina; Richards, Mark W; Huguenin-Dezot, Nicolas; Chin, Jason W; Kennedy, Eileen J; Pfuhl, Mark; Royle, Stephen J; Gergely, Fanni; Bayliss, Richard.

EMBO J ; 37(8)2018 04 13.

Artigo em Inglês | MEDLINE | ID: mdl-29510984

4.

Molecular causes of primary microcephaly and related diseases: a report from the UNIA Workshop.

Stracker, Travis H; Morrison, Ciaran G; Gergely, Fanni.

Chromosoma ; 129(2): 115-120, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32424716

5.

Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis.

Stojic, Lovorka; Lun, Aaron T L; Mangei, Jasmin; Mascalchi, Patrice; Quarantotti, Valentina; Barr, Alexis R; Bakal, Chris; Marioni, John C; Gergely, Fanni; Odom, Duncan T.

Nucleic Acids Res ; 46(12): 5950-5966, 2018 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-29860520

6.

Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly.

Burgess, Selena G; Peset, Isabel; Joseph, Nimesh; Cavazza, Tommaso; Vernos, Isabelle; Pfuhl, Mark; Gergely, Fanni; Bayliss, Richard.

PLoS Genet ; 11(7): e1005345, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-26134678

7.

Hitting the brakes: targeting microtubule motors in cancer.

Chandrasekaran, Gayathri; Tátrai, Péter; Gergely, Fanni.

Br J Cancer ; 113(5): 693-8, 2015 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-26180922

8.

Centrosomes and mitotic spindle poles: a recent liaison?

Chavali, Pavithra L; Peset, Isabel; Gergely, Fanni.

Biochem Soc Trans ; 43(1): 13-8, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25619241

9.

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

McIntyre, Rebecca E; Lakshminarasimhan Chavali, Pavithra; Ismail, Ozama; Carragher, Damian M; Sanchez-Andrade, Gabriela; Forment, Josep V; Fu, Beiyuan; Del Castillo Velasco-Herrera, Martin; Edwards, Andrew; van der Weyden, Louise; Yang, Fengtang; Ramirez-Solis, Ramiro; Estabel, Jeanne; Gallagher, Ferdia A; Logan, Darren W; Arends, Mark J; Tsang, Stephen H; Mahajan, Vinit B; Scudamore, Cheryl L; White, Jacqueline K; Jackson, Stephen P; Gergely, Fanni; Adams, David J.

PLoS Genet ; 8(11): e1003022, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-23166506

10.

The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.

Bakircioglu, Mehmet; Carvalho, Ofélia P; Khurshid, Maryam; Cox, James J; Tuysuz, Beyhan; Barak, Tanyeri; Yilmaz, Saliha; Caglayan, Okay; Dincer, Alp; Nicholas, Adeline K; Quarrell, Oliver; Springell, Kelly; Karbani, Gulshan; Malik, Saghira; Gannon, Caroline; Sheridan, Eamonn; Crosier, Moira; Lisgo, Steve N; Lindsay, Susan; Bilguvar, Kaya; Gergely, Fanni; Gunel, Murat; Woods, C Geoffrey.

Am J Hum Genet ; 88(5): 523-35, 2011 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-21529752

11.

Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.

Carden, Sarah; Vitiello, Elisa; Rosa E Silva, Ivan; Holder, James; Quarantotti, Valentina; Kishore, Kamal; Roamio Franklin, Valar Nila; D'Santos, Clive; Ochi, Takashi; van Breugel, Mark; Gergely, Fanni.

Dev Cell ; 58(21): 2393-2410.e9, 2023 11 06.

Artigo em Inglês | MEDLINE | ID: mdl-37852252

12.

A histone deacetylase 3 and mitochondrial complex I axis regulates toxic formaldehyde production.

Wit, Niek; Gogola, Ewa; West, James A; Vornbäumen, Tristan; Seear, Rachel V; Bailey, Peter S J; Burgos-Barragan, Guillermo; Wang, Meng; Krawczyk, Patrycja; Huberts, Daphne H E W; Gergely, Fanni; Matheson, Nicholas J; Kaser, Arthur; Nathan, James A; Patel, Ketan J.

Sci Adv ; 9(20): eadg2235, 2023 05 19.

Artigo em Inglês | MEDLINE | ID: mdl-37196082

13.

Cilia born out of shock and stress.

Chavali, Pavithra L; Gergely, Fanni.

EMBO J ; 32(23): 3011-3, 2013 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-24185901

14.

Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells.

Bulstrode, Harry; Girdler, Gemma C; Gracia, Tannia; Aivazidis, Alexander; Moutsopoulos, Ilias; Young, Adam M H; Hancock, John; He, Xiaoling; Ridley, Katherine; Xu, Zhaoyang; Stockley, John H; Finlay, John; Hallou, Clement; Fajardo, Teodoro; Fountain, Daniel M; van Dongen, Stijn; Joannides, Alexis; Morris, Robert; Mair, Richard; Watts, Colin; Santarius, Thomas; Price, Stephen J; Hutchinson, Peter J A; Hodson, Emma J; Pollard, Steven M; Mohorianu, Irina; Barker, Roger A; Sweeney, Trevor R; Bayraktar, Omer; Gergely, Fanni; Rowitch, David H.

Neuron ; 110(23): 3936-3951.e10, 2022 12 07.

Artigo em Inglês | MEDLINE | ID: mdl-36174572

15.

Mitosis: Cdh1 clears the way for anaphase spindle assembly.

Gergely, Fanni.

Curr Biol ; 18(21): R1009-12, 2008 Nov 11.

Artigo em Inglês | MEDLINE | ID: mdl-19000797

16.

Accessorizing the centrosome: new insights into centriolar appendages and satellites.

Tischer, Julia; Carden, Sarah; Gergely, Fanni.

Curr Opin Struct Biol ; 66: 148-155, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33279729

17.

A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division.

Stojic, Lovorka; Lun, Aaron T L; Mascalchi, Patrice; Ernst, Christina; Redmond, Aisling M; Mangei, Jasmin; Barr, Alexis R; Bousgouni, Vicky; Bakal, Chris; Marioni, John C; Odom, Duncan T; Gergely, Fanni.

Nat Commun ; 11(1): 1851, 2020 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-32296040

18.

CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.

Ochi, Takashi; Quarantotti, Valentina; Lin, Huawen; Jullien, Jerome; Rosa E Silva, Ivan; Boselli, Francesco; Barnabas, Deepak D; Johnson, Christopher M; McLaughlin, Stephen H; Freund, Stefan M V; Blackford, Andrew N; Kimata, Yuu; Goldstein, Raymond E; Jackson, Stephen P; Blundell, Tom L; Dutcher, Susan K; Gergely, Fanni; van Breugel, Mark.

Structure ; 28(6): 674-689.e11, 2020 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-32375023

19.

Knock-in and knock-out: the use of reverse genetics in somatic cells to dissect mitotic pathways.

Barr, Alexis R; Zyss, Deborah; Gergely, Fanni.

Methods Mol Biol ; 545: 1-19, 2009.

Artigo em Inglês | MEDLINE | ID: mdl-19475379

20.

BRCTx is a novel, highly conserved RAD18-interacting protein.

Adams, David J; van der Weyden, Louise; Gergely, Fanni V; Arends, Mark J; Ng, Bee Ling; Tannahill, David; Kanaar, Roland; Markus, Andrea; Morris, Brian J; Bradley, Allan.

Mol Cell Biol ; 25(2): 779-88, 2005 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-15632077

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