[Clinical course of cryptococcosis in HIV infection]. / Klinicheskoe techenie kriptokokkoza pri BICh-infektsii.

Cryptococcosis was detected in 17% of examines with AIDS. The disease was caused by fungus Cryptococcus neoformans. Most frequently cryptococcosis affected CNS (meningitis and encephalitis). The symptoms were scare and nonspecific, e.g. positive meningitis indicators occurred only in 9% of the patients. Cryptococcosis tends to hematogenic spread with severe dissemination. The diagnosis was made primarily basing on the results of mycological investigations of the biosubstrates, i.e. discovery of Cryptococcus neoformans.

[The clinical picture of mycotic complications in HIV-infected patients]. / Klinika mikoticheskikh oslozhnenii u VICh-infitsirovannykh bol'nykh.

Mycotic complications were registered in 21 out of 37 HIV-infected subjects. Oropharyngeal candidiasis was most common. It occurred prior to or concurrently with esophageal and skin candidiasis, fungemia, meningoencephalitis and disseminated lesions. With immunodeficiency progression, the prevalence and severity of mycosis go up. The causing fungi vary in great range: Candida albicans, Candida krusei. Candida tropicalis, Candida pseudotropicalis, Candida parapsilosis. Cryptococcus neoformans, Rhodotorula rubra, Penicillium chrysogenum.

[Current principles of diagnosis of cavitary formations in the lungs]. / Sovremennye printsipy diagnostiki polostnykh obrazovanii v legkikh.

Tuberculosis, cancer or abscessed pneumonia were diagnosed in 141 (84%) of the 168 patients who had solitary cavities in the lungs in the absence of M. tuberculosis or cancer cells isolation. The most informative diagnostic signs in these cases are provided by sex, age, special features of the onset and course of the disease in the period between diagnosis establishment and patients' hospitalization, data obtained when fluorograms taken from archives were compared with the X-ray picture at the moment of disease detection as well as by the results of serological reactions such as tuberculous antigen detection and Mantoux test, and blood level fibrinogen determination. On the second stage of examination the supplementary signs were obtained in bronchoscopy, cytologic examination of the bronchial contents after prescription of irritating inhalations and prednisolone test and immunologic study. Correct diagnosis can be established in 99% of the cases in the presence of simultaneously five and more significant signs.

[Tuberculosis and pneumonia]. / Tuberkulez i pnevmonia.

Analysis of the clinical course of acute pneumonia in pulmonary tuberculosis patients is presented. The lowest rate of acute pneumonia morbidity was found in patients with active tuberculosis during antituberculosis therapy. As soon as the specific process subsides and its activity diminishes acute pneumonia morbidity grows. Specific features of the course of acute pneumonia in patients with different phases of tuberculosis development are shown. Data on the study of liquid-crystal thermography are presented as well as the assessment of the capillary blood flow and the results of immunologic study in the presence of combined pathology. The terms of alleviation of acute pneumonia in tuberculosis patients are delayed, especially in inflammation development in the zones of post-tuberculosis changes.