Detalhe da pesquisa
1.
Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform.
Bioorg Med Chem Lett
; 24(23): 5450-4, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25454270
2.
N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.
J Am Chem Soc
; 135(27): 9968-71, 2013 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23782398
3.
Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.
Biochem J
; 430(3): 461-76, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20632995
4.
Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route.
J Med Chem
; 64(10): 6902-6923, 2021 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34000802
5.
Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome.
Bioorg Med Chem Lett
; 20(22): 6581-6, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20875739
6.
Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8.
J Med Chem
; 50(3): 566-84, 2007 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17266208
7.
N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists.
J Med Chem
; 48(26): 8182-93, 2005 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16366600
8.
Discovery of an opioid kappa receptor selective pure antagonist from a library of N-substituted 4beta-methyl-5-(3-hydroxyphenyl)morphans.
J Med Chem
; 45(16): 3524-30, 2002 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12139463
9.
Potent histone deacetylase inhibitors derived from 4-(aminomethyl)-N-hydroxybenzamide with high selectivity for the HDAC6 isoform.
J Med Chem
; 56(18): 7201-11, 2013 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23964961