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1.
IEEE Trans Robot ; 34(3): 748-763, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30662378

RESUMO

In this paper, we develop theoretical foundations for a new class of rehabilitation robot: body powered devices that route power between a user's joints. By harvesting power from a healthy joint to assist an impaired joint, novel bimanual and self-assist therapies are enabled. This approach complements existing robotic therapies aimed at promoting recovery of motor function after neurological injury. We employ hydraulic transmissions for routing power, or equivalently for coupling the motions of a user's joints. Fluid power routed through flexible tubing imposes constraints within a limb or between homologous joints across the body. Variable transmissions allow constraints to be steered on the fly, and simple valve switching realizes free space and locked motion. We examine two methods for realizing variable hydraulic transmissions: using valves to switch among redundant cylinders (digital hydraulics) or using an intervening electromechanical link. For both methods, we present a rigorous mathematical framework for describing and controlling the resulting constraints. Theoretical developments are supported by experiments using a prototype fluid-power exoskeleton.

2.
J Neuroeng Rehabil ; 14(1): 33, 2017 04 24.
Artigo em Inglês | MEDLINE | ID: mdl-28438166

RESUMO

BACKGROUND: Regenerative Peripheral Nerve Interfaces (RPNIs) are neurotized muscle grafts intended to produce electromyographic signals suitable for motorized prosthesis control. Two RPNIs producing independent agonist/antagonist signals are required for each control axis; however, it is unknown whether signals from adjacent RPNIs are independent. The purpose of this work was to determine signaling characteristics from two adjacent RPNIs, the first neurotized by a foot dorsi-flexor nerve and the second neurotized by a foot plantar-flexor nerve in a rodent model. METHODS: Two Control group rats had electrodes implanted onto the soleus (tibial nerve) and extensor digitorum longus (peroneal nerve) muscles in the left hind limb. Two Dual-RPNI group rats had two separate muscles grafted to the left thigh and each implanted with electrodes: the extensor digitorum longus was neurotized with a transected fascicle from the tibial nerve, and the tibialis anterior was implanted with a transected peroneal nerve. Four months post-surgery, rats walked on a treadmill, were videographed, and electromyographic signals were recorded. Amplitude and periodicity of all signals relative to gait period were quantified. To facilitate comparisons across groups, electromyographic signals were expressed as a percent of total stepping cycle activity for each stance and swing gait phase. Independence between peroneal and tibial nerve activations were assessed by statistical comparisons between groups during stance and swing. RESULTS: Electromyographic activity for Control and Dual-RPNI rats displayed alternating activation patterns coinciding with stance and swing. Significant signal amplitude differences between the peroneal and tibial nerves were found in both the Control and Dual-RPNI groups. Non-inferiority tests performed on Dual-RPNI group signal confidence intervals showed that activation was equivalent to the Control group in all but the peroneal RPNI construct during stance. The similar electromyographic activity obtained for Control and RPNI suggests the latter constructs activate independently during both stance and swing, and contain minimal crosstalk. CONCLUSIONS: In-vivo myoelectric RPNI activity encodes neural activation patterns associated with gait. Adjacent RPNIs neurotized with agonist/antagonist nerves display activity amplitudes similar to Control during voluntary walking. The distinct and expected activation patterns indicate the RPNI may provide independent signaling in humans, suitable for motorized prosthesis control.


Assuntos
Regeneração Nervosa/fisiologia , Nervos Periféricos/fisiologia , Caminhada/fisiologia , Animais , Eletrodos Implantados , Eletromiografia , Pé/inervação , Pé/fisiologia , Marcha/fisiologia , Membro Posterior/inervação , Membro Posterior/fisiologia , Masculino , Músculo Esquelético/inervação , Músculo Esquelético/fisiologia , Nervo Fibular/fisiologia , Ratos , Ratos Endogâmicos F344 , Nervo Tibial/fisiologia
3.
J Neuroeng Rehabil ; 12: 104, 2015 Nov 25.
Artigo em Inglês | MEDLINE | ID: mdl-26602538

RESUMO

BACKGROUND: Haptic display technologies are well suited to relay proprioceptive, force, and contact cues from a prosthetic terminal device back to the residual limb and thereby reduce reliance on visual feedback. The ease with which an amputee interprets these haptic cues, however, likely depends on whether their dynamic signal behavior corresponds to expected behaviors-behaviors consonant with a natural limb coupled to the environment. A highly geared motor in a terminal device along with the associated high back-drive impedance influences dynamic interactions with the environment, creating effects not encountered with a natural limb. Here we explore grasp and lift performance with a backdrivable (low backdrive impedance) terminal device placed under proportional myoelectric position control that features referred haptic feedback. METHODS: We fabricated a back-drivable terminal device that could be used by amputees and non-amputees alike and drove aperture (or grip force, when a stiff object was in its grasp) in proportion to a myoelectric signal drawn from a single muscle site in the forearm. In randomly ordered trials, we assessed the performance of N=10 participants (7 non-amputee, 3 amputee) attempting to grasp and lift an object using the terminal device under three feedback conditions (no feedback, vibrotactile feedback, and joint torque feedback), and two object weights that were indiscernible by vision. RESULTS: Both non-amputee and amputee participants scaled their grip force according to the object weight. Our results showed only minor differences in grip force, grip/load force coordination, and slip as a function of sensory feedback condition, though the grip force at the point of lift-off for the heavier object was significantly greater for amputee participants in the presence of joint torque feedback. An examination of grip/load force phase plots revealed that our amputee participants used larger safety margins and demonstrated less coordination than our non-amputee participants. CONCLUSIONS: Our results suggest that a backdrivable terminal device may hold advantages over non-backdrivable devices by allowing grip/load force coordination consistent with behaviors observed in the natural limb. Likewise, the inconclusive effect of referred haptic feedback on grasp and lift performance suggests the need for additional testing that includes adequate training for participants.


Assuntos
Amputados/reabilitação , Membros Artificiais , Retroalimentação Sensorial/fisiologia , Força da Mão/fisiologia , Adulto , Impedância Elétrica , Feminino , Antebraço , Humanos , Masculino , Adulto Jovem
4.
J Neuroeng Rehabil ; 11: 102, 2014 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-24920401

RESUMO

BACKGROUND: Control of reaching movements for manual work, vehicle operation, or interactions with manual interfaces requires concurrent gaze control for visual guidance of the hand. We hypothesize that reaching movements are based on negotiated strategies to resolve possible conflicting demands placed on body segments shared by the visual (gaze) and manual (hand) control systems. Further, we hypothesize that a multiplicity of possible spatial configurations (redundancy) in a movement system enables a resolution of conflicting demands that does not require sacrificing the goals of the two systems. METHODS: The simultaneous control of manual reach and gaze during seated reaching movements was simulated by solving an inverse kinematics model wherein joint trajectories were estimated from a set of recorded hand and head movements. A secondary objective function, termed negotiation function, was introduced to describe a means for the manual reach and gaze directing systems to balance independent goals against (possibly competing) demands for shared resources, namely the torso movement. For both systems, the trade-off may be resolved without sacrificing goal achievement by taking advantage of redundant degrees of freedom. Estimated joint trajectories were then compared to joint movement recordings from ten participants. Joint angles were predicted with and without the negotiation function in place, and model accuracy was determined using the root-mean-square errors (RMSEs) and differences between estimated and recorded joint angles. RESULTS: The prediction accuracy was generally improved when negotiation was included: the negotiated control reduced RMSE by 16% and 30% on average when compared to the systems with only manual or visual control, respectively. Furthermore, the RMSE in the negotiated control system tended to improve with torso movement amplitude. CONCLUSIONS: The proposed model describes how multiple systems cooperate to perform goal-directed human movements when those movements draw upon shared resources. Allocation of shared resources can be undertaken by a negotiation process that is aware of redundancies and the existence of multiple solutions within the individual systems.


Assuntos
Algoritmos , Simulação por Computador , Destreza Motora/fisiologia , Fenômenos Biomecânicos , Feminino , Fixação Ocular/fisiologia , Mãos/fisiologia , Humanos , Masculino , Adulto Jovem
5.
Emerg Radiol ; 19(2): 141-8, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22198736

RESUMO

Excessive obesity poses a significant limitation to radiographic magnetic resonance imaging (MRI), particularly related to aperture or bore diameter due to the patient's girth. Determination of whether a patient will fit into the bore of the MRI scanner is currently accomplished using patient height, weight, and MRI technician experience. These simple methods have proven unreliable. We sought to develop a device and method which could accurately determine whether a patient would fit into the MRI scanner. We developed an MRI template prototype which was tested against the standard radiology methods in a pilot study (n = 6). We then performed a prospective validation study in adult human volunteers (n = 100) to assess the accuracy of the MRI template. We collected height, weight, shoulder and pelvis girth/diameter for each study participant to evaluate the body dimension measurements that would assist in determination of whether a patient would fit into the MRI scanner. Using the MRI template, we determined that 11 of the 100 study participants would not fit in the MRI scanner and 10 were confirmed to not fit into the MRI aperture [positive predictive value (PPV) 0.91 (0.58-0.99); negative predictive value (NPV) 1.00 (0.95-1.00), sensitivity 1.00 (0.69-1.00), specificity 0.99 (0.93-0.99), likelihood ratio positive test 90 (12.81-632), likelihood ratio negative test 0, accuracy 99%]. In comparison, the body measurement method did not perform as well [PPV 0.66 (0.34-0.90), NPV 0.97 (0.92-0.99), sensitivity 0.80 (0.44-0.97), specificity 0.95 (0.89-0.98), likelihood ratio positive test 17.97 (6.56-49.2), likelihood ratio negative test 0.209 (0.06-0.72), accuracy 94%]. This study confirmed that the use of an MRI template is an accurate tool in determining whether an obese patient can fit through the MRI bore and be accommodated in the MRI scanner.


Assuntos
Tamanho Corporal , Imageamento por Ressonância Magnética/instrumentação , Obesidade , Ferimentos e Lesões/diagnóstico , Desenho de Equipamento , Feminino , Humanos , Funções Verossimilhança , Masculino , Projetos Piloto , Valor Preditivo dos Testes , Estudos Prospectivos , Sensibilidade e Especificidade
6.
Plast Reconstr Surg ; 149(6): 1149e-1154e, 2022 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-35404335

RESUMO

SUMMARY: Without meaningful and intuitive sensory feedback, even the most advanced prosthetic limbs remain insensate and impose an enormous cognitive burden during use. The regenerative peripheral nerve interface can serve as a novel bidirectional motor and sensory neuroprosthetic interface. In previous human studies, regenerative peripheral nerve interfaces demonstrated stable high-amplitude motor electromyography signals with excellent signal-to-noise ratio for prosthetic control. In addition, they can treat and prevent postamputation pain by mitigating neuroma formation. In this study, the authors investigated whether electrical stimulation applied to regenerative peripheral nerve interfaces could produce appreciable proprioceptive and/or tactile sensations in two participants with upper limb amputations. Stimulation of the interfaces resulted in both participants reporting proprioceptive sensations in the phantom hand. Specifically, stimulation of participant 1's median nerve regenerative peripheral nerve interface activated a flexion sensation in the thumb or index finger, whereas stimulation of the ulnar nerve interface evoked a flexion sensation of the ring or small finger. Likewise, stimulation of one of participant 2's ulnar nerve interfaces produced a sensation of flexion at the ring finger distal interphalangeal joint. In addition, stimulation of participant 2's other ulnar nerve interface and the median nerve interface resulted in perceived cutaneous sensations that corresponded to each nerve's respective dermatome. These results suggest that regenerative peripheral nerve interfaces have the potential to restore proprioceptive and cutaneous sensory feedback that could significantly improve prosthesis use and embodiment.


Assuntos
Membros Artificiais , Amputação Cirúrgica , Humanos , Nervos Periféricos/fisiologia , Propriocepção , Extremidade Superior/cirurgia
7.
Artigo em Inglês | MEDLINE | ID: mdl-34516377

RESUMO

Sensory feedback from body-powered and myoelectric prostheses are limited, but in different ways. Currently, there are no empirical studies on how incidental feedback differs between body-powered and myoelectric prostheses, or how these differences impact grasping. Thus, the purpose of this study was to quantify differences in grasping performance between body-powered and myoelectric prosthesis users when presented with different forms of feedback. Nine adults with upper limb loss and nine without (acting as controls) completed two tasks in a virtual environment. In the first task, participants used visual, vibration, or force feedback to assist in matching target grasp apertures. In the second task, participants used either visual or force feedback to identify the stiffness of a virtual object. Participants using either prosthesis type improved their accuracy and reduced their variability compared to the no feedback condition when provided with any form of feedback (p < 0.001). However, participants using body-powered prostheses were significantly more accurate and less variable at matching grasp apertures than those using myoelectric prostheses across all feedback conditions. When identifying stiffness, body-powered prosthesis users were more accurate using force feedback (64% compared to myoelectric users' 39%) while myoelectric users were more accurate using visual feedback (65% compared to body-powered users' 53%). This study supports previous findings that body-powered prosthesis users receive limited force and proprioceptive feedback, while myoelectric prosthesis users receive almost no force or proprioceptive feedback from their device. This work can inform future supplemental feedback that enhances rather than reproduces existing incidental feedback.


Assuntos
Amputados , Membros Artificiais , Adulto , Eletromiografia , Retroalimentação , Retroalimentação Sensorial , Força da Mão , Humanos , Desenho de Prótese
8.
Rev Sci Instrum ; 92(11): 114101, 2021 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-34852501

RESUMO

The mechanotransduction pathways that mediate cellular responses to contact forces are better understood than those that mediate response to distance forces, especially the force of gravity. Removing or reducing gravity for significant periods of time involves either sending samples to space, inducing diamagnetic levitation with high magnetic fields, or continually reorienting samples for a period, all in a manner that supports cell culturing. Undesired secondary effects due to high magnetic fields or shear forces associated with fluid flow while reorienting must be considered in the design of ground-based devices. We have developed a lab-friendly and compact random positioning machine (RPM) that fits in a standard tissue culture incubator. Using a two-axis gimbal, it continually reorients samples in a manner that produces an equal likelihood that all possible orientations are visited. We contribute a new control algorithm by which the distribution of probabilities over all possible orientations is completely uniform. Rather than randomly varying gimbal axis speed and/or direction as in previous algorithms (which produces non-uniform probability distributions of orientation), we use inverse kinematics to follow a trajectory with a probability distribution of orientations that is uniform by construction. Over a time period of 6 h of operation using our RPM, the average gravity is within 0.001 23% of the gravity of Earth. Shear forces are minimized by limiting the angular speed of both gimbal motors to under 42 °/s. We demonstrate the utility of our RPM by investigating the effects of simulated microgravity on adherent human osteoblasts immediately after retrieving samples from our RPM. Cytoskeletal disruption and cell shape changes were observed relative to samples cultured in a 1 g environment. We also found that subjecting human osteoblasts in suspension to simulated microgravity resulted in less filamentous actin and lower cell stiffness.


Assuntos
Ausência de Peso , Células Cultivadas , Humanos , Mecanotransdução Celular , Osteoblastos , Simulação de Ausência de Peso
9.
Sci Transl Med ; 12(533)2020 03 04.
Artigo em Inglês | MEDLINE | ID: mdl-32132217

RESUMO

Peripheral nerves provide a promising source of motor control signals for neuroprosthetic devices. Unfortunately, the clinical utility of current peripheral nerve interfaces is limited by signal amplitude and stability. Here, we showed that the regenerative peripheral nerve interface (RPNI) serves as a biologically stable bioamplifier of efferent motor action potentials with long-term stability in upper limb amputees. Ultrasound assessments of RPNIs revealed prominent contractions during phantom finger flexion, confirming functional reinnervation of the RPNIs in two patients. The RPNIs in two additional patients produced electromyography signals with large signal-to-noise ratios. Using these RPNI signals, subjects successfully controlled a hand prosthesis in real-time up to 300 days without control algorithm recalibration. RPNIs show potential in enhancing prosthesis control for people with upper limb loss.


Assuntos
Amputados , Membros Artificiais , Eletromiografia , Mãos , Humanos , Nervos Periféricos , Extremidade Superior
10.
IEEE Trans Haptics ; 12(2): 205-216, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30582553

RESUMO

The study of haptic perception often makes use of haptic rendering to display the variety of impedances needed to run an experiment. Unacknowledged in many cases is the influence of the selected device hardware on what the user will feel, particularly in interactions featuring frequencies above the control bandwidth. While human motion is generally limited to 10 Hz, virtual environments with unilateral constraints are subject to excitation of a wider frequency spectrum through contact transitions. We employ the effective impedance decomposition to discuss the effects of parasitics outside the rendering bandwidth. We also introduce an analysis of the admittance and impedance controllers with respect to sensitivity to load cell noise. We explore these effects using a single degree-of-freedom device that can be configured for either a low or high mechanical advantage in a perceptual experiment, with experimental conditions designed through application of the effective impedance decomposition. We find that the excitation of high frequencies through contact transitions negatively impacts humans' ability to distinguish between stiffnesses.


Assuntos
Percepção do Tato/fisiologia , Impedância Elétrica , Humanos , Interface Usuário-Computador
11.
Restor Neurol Neurosci ; 36(6): 693-708, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30400120

RESUMO

BACKGROUND: Robotic rehabilitation is a highly promising approach to recover lost functions after stroke or other neurological disorders. Unfortunately, robotic rehabilitation currently suffers from "motor slacking", a phenomenon in which the human motor system reduces muscle activation levels and movement excursions, ostensibly to minimize metabolic- and movement-related costs. Consequently, the patient remains passive and is not fully engaged during therapy. To overcome this limitation, we envision a new class of body-powered robots and hypothesize that motor slacking could be reduced if individuals must provide the power to move their impaired limbs via their own body (i.e., through the motion of a healthy limb). OBJECTIVE: To test whether a body-powered exoskeleton (i.e. robot) could reduce motor slacking during robotic training. METHODS: We developed a body-powered robot that mechanically coupled the motions of the user's elbow joints. We tested this passive robot in two groups of subjects (stroke and able-bodied) during four exercise conditions in which we controlled whether the robotic device was powered by the subject or by the experimenter, and whether the subject's driven arm was engaged or at rest. Motor slacking was quantified by computing the muscle activation changes of the elbow flexor and extensor muscles using surface electromyography. RESULTS: Subjects had higher levels of muscle activation in their driven arm during self-powered conditions compared to externally-powered conditions. Most notably, subjects unintentionally activated their driven arm even when explicitly told to relax when the device was self-powered. This behavior was persistent throughout the trial and did not wane after the initiation of the trial. CONCLUSIONS: Our findings provide novel evidence indicating that motor slacking can be reduced by self-powered robots; thus demonstrating promise for rehabilitation of impaired subjects using this new class of wearable system. The results also serve as a foundation to develop more sophisticated body-powered robots (e.g., with controllable transmissions) for rehabilitation purposes.


Assuntos
Terapia por Exercício/instrumentação , Terapia por Exercício/métodos , Robótica , Reabilitação do Acidente Vascular Cerebral/métodos , Acidente Vascular Cerebral , Extremidade Superior/fisiologia , Adolescente , Adulto , Idoso , Análise de Variância , Eletromiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Músculo Esquelético/fisiopatologia , Estudo de Prova de Conceito , Amplitude de Movimento Articular , Adulto Jovem
12.
IEEE Trans Haptics ; 11(3): 476-481, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29035226

RESUMO

Refreshable displays for tactile graphics are typically composed of pins that have smaller diameters and spacing than standard braille dots. We investigated configurations of high-density pins to form braille text on such displays using non-refreshable stimuli produced with a 3D printer. Normal dot braille (diameter 1.5 mm) was compared to high-density dot braille (diameter 0.75 mm) wherein each normal dot was rendered by high-density simulated pins alone or in a cluster of pins configured in a diamond, X, or square; and to "blobs" that could result from covering normal braille and high-density multi-pin configurations with a thin membrane. Twelve blind participants read MNREAD sentences displayed in these conditions. For high-density simulated pins, single pins were as quickly and easily read as normal braille, but diamond, X, and square multi-pin configurations were slower and/or harder to read than normal braille. We therefore conclude that as long as center-to-center dot spacing and dot placement is maintained, the dot diameter may be open to variability for rendering braille on a high density tactile display.


Assuntos
Cegueira/psicologia , Leitura , Auxiliares Sensoriais , Percepção do Tato , Adulto , Desenho de Equipamento , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estimulação Física , Tato , Interface Usuário-Computador , Pessoas com Deficiência Visual
13.
J Mot Behav ; 39(3): 179-93, 2007 May.
Artigo em Inglês | MEDLINE | ID: mdl-17550870

RESUMO

The authors employed a virtual environment to investigate how humans use haptic and visual feedback in a simple, rhythmic object-manipulation task. The authors hypothesized that feedback would help participants identify the appropriate resonant frequency and perform online control adjustments. The 1st test was whether sensory feedback is needed at all; the 2nd was whether the motor system combines visual and haptic feedback to improve performance. Task performance was quantified in terms of work performed on the virtual inertia, ability to identify the correct rhythm, and variability of movement. Strict feedforward control was found to be ineffective for this task, even when participants had previous knowledge of the rhythm. Participants (N = 11) performed far better when feedback was available (11 times more work, 2.2 times more precise frequency, 30% less variability; p < .05 for all 3 performance measures). Using sensory feedback, participants were able to rapidly identify 4 different spring-inertia systems without foreknowledge of the corresponding resonant frequencies. They performed over 20% more work with 24% less variability when provided with both visual and haptic feedback than they did with either feedback channel alone (p < .05), providing evidence that they integrated online sensory channels. Whereas feedforward control alone led to poor performance, feedback control led to fast tuning or calibration of control according to the resonant frequency of the object, and to better control of the rhythmic movement itself.


Assuntos
Retroalimentação Psicológica/fisiologia , Cinestesia/fisiologia , Desempenho Psicomotor/fisiologia , Tato/fisiologia , Percepção Visual/fisiologia , Adaptação Psicológica , Adulto , Algoritmos , Análise de Variância , Feminino , Mãos/inervação , Mãos/fisiologia , Força da Mão , Humanos , Masculino , Modelos Psicológicos , Reconhecimento Fisiológico de Modelo/fisiologia , Análise e Desempenho de Tarefas
14.
Comput Biol Med ; 37(7): 1009-19, 2007 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-17067566

RESUMO

This work investigates the control of horizontal head movements in the context of unconstrained visually guided head and arm/finger aiming tasks. In a first experiment, the head was free to move while gaze was directed at randomly presented eccentric targets distributed horizontally (0 degrees-120 degrees) at eye level. In a second experiment, the horizontal head orientation was constrained to predetermined positions (0 degrees, 15 degrees, 30 degrees, 45 degrees or 60 degrees rightward) while the right index finger aimed at targets with the arm fully extended. Kinematics of head movements in gaze displacements exhibits an initial component weakly correlated with target position, followed by multiple corrections. Since the eyes are assumed to already be aimed at the target when the corrections occur, it is suggested that one goal of head movement control is to achieve a desired final orientation (posture). This hypothesis is supported by results from the second experiment that reveal an association between eye/head orientation angles and errors exhibited in the visuo-spatial representation of the environment. The minimization of error then underlies the control of head movement as a postural response optimized for a given target and task condition.


Assuntos
Movimentos da Cabeça/fisiologia , Postura/fisiologia , Percepção Visual/fisiologia , Adulto , Fenômenos Biomecânicos , Engenharia Biomédica , Simulação por Computador , Feminino , Humanos , Masculino , Modelos Biológicos , Propriocepção/fisiologia , Desempenho Psicomotor/fisiologia , Análise e Desempenho de Tarefas
15.
IEEE Trans Neural Syst Rehabil Eng ; 25(3): 215-226, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-27101614

RESUMO

Myoelectric prostheses have many advantages over body-powered prostheses, yet the absence of sensory feedback in myoelectric devices is one reason body-powered devices are often preferred by amputees. While considerable progress has been made in the mechanical design and control of myoelectric prostheses, research on haptic feedback has not had a similar impact. In this study, we seek to develop a fundamental understanding of the utility of force feedback and vision in the functional operation of a body-powered upper-limb prosthesis. Using a custom body-powered prosthesis in which force feedback can be conditionally removed, we asked N=10 non-amputee participants to identify objects based on stiffness in four separate conditions with and without visual and/or force feedback. Results indicate that the combination of visual and force feedback allows for the best accuracy, followed by force feedback only, then visual feedback only. In addition, combining force feedback with visual feedback does not significantly affect identification timing compared to visual feedback alone. These findings suggest that consideration should be given to the development of force feedback displays for myoelectric prostheses that function like a Bowden cable, coupling the amputee's control input to the resulting feedback.


Assuntos
Membros Artificiais , Exoesqueleto Energizado , Retroalimentação Sensorial , Modelos Biológicos , Desempenho Psicomotor , Tato , Amputados/reabilitação , Análise de Falha de Equipamento , Humanos , Desenho de Prótese
16.
IEEE Trans Neural Syst Rehabil Eng ; 14(3): 390-7, 2006 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-17009499

RESUMO

We tested whether humans can learn to sense and compensate for interaction forces in contact tasks. Many tasks, such as use of hand tools, involve significant interaction forces between hand and environment. One control strategy would be to use high hand impedance to reduce sensitivity to these forces. But an alternative would be to learn feedback compensation for the extrinsic dynamics and associated interaction forces, with the potential for lower control effort. We observed subjects as they learned control of a ball-and-beam system, a visuo-motor task where the goal was to quickly position a ball rolling atop a rotating beam, through manual rotation of the beam alone. We devised a ball-and-beam apparatus that could be operated in a real mode, where a physical ball was present; or in a virtual training mode, where the ball's dynamics were simulated in real time. The apparatus presented the same visual feedback in all cases, and optionally produced haptic feedback of the interaction forces associated with the ball's motion. Two healthy adult subject groups, vision-only and vision-haptics (each n= 10), both trained for 80 trials on the simulated system, and then were evaluated on the real system to test for skill transfer effects. If humans incorporate interaction forces in their learning, the vision-haptics group would be expected to exhibit a smoother transfer, as quantified by changes in completion time of a ball-positioning task. During training, both groups adapted well to the task, with reductions of 64%-70% in completion time. At skill transfer to the real system, the vision-only group had a significant 35% increase in completion time (p < 0.05). There was no significant change in the vision-haptics group, indicating that subjects had learned to compensate for interaction forces. These forces could potentially be incorporated in virtual environments to assist with motor training or rehabilitation.


Assuntos
Destreza Motora/fisiologia , Movimento/fisiologia , Músculo Esquelético/fisiologia , Equilíbrio Postural/fisiologia , Análise e Desempenho de Tarefas , Tato/fisiologia , Percepção Visual/fisiologia , Adaptação Fisiológica/fisiologia , Retroalimentação/fisiologia , Humanos , Estresse Mecânico , Extremidade Superior/fisiologia
17.
Ann Biomed Eng ; 44(9): 2760-73, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-26817456

RESUMO

Functional strength training is becoming increasingly popular when rehabilitating individuals with neurological injury such as stroke or cerebral palsy. Typically, resistance during walking is provided using cable robots or weights that are secured to the distal shank of the subject. However, there exists no device that is wearable and capable of providing resistance across the joint, allowing over ground gait training. In this study, we created a lightweight and wearable device using eddy current braking to provide resistance to the knee. We then validated the device by having subjects wear it during a walking task through varying resistance levels. Electromyography and kinematics were collected to assess the biomechanical effects of the device on the wearer. We found that eddy current braking provided resistance levels suitable for functional strength training of leg muscles in a package that is both lightweight and wearable. Applying resistive forces at the knee joint during gait resulted in significant increases in muscle activation of many of the muscles tested. A brief period of training also resulted in significant aftereffects once the resistance was removed. These results support the feasibility of the device for functional strength training during gait. Future research is warranted to test the clinical potential of the device in an injured population.


Assuntos
Eletromiografia , Marcha/fisiologia , Articulação do Joelho/fisiologia , Músculo Esquelético/fisiologia , Aptidão Física/psicologia , Fenômenos Biomecânicos , Eletromiografia/instrumentação , Eletromiografia/métodos , Feminino , Humanos , Masculino
18.
J Neural Eng ; 13(2): 026012, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26859115

RESUMO

OBJECTIVE: Regenerative peripheral nerve interfaces (RPNIs) are neurotized free autologous muscle grafts equipped with electrodes to record myoelectric signals for prosthesis control. Viability of rat RPNI constructs have been demonstrated using evoked responses. In vivo RPNI characterization is the next critical step for assessment as a control modality for prosthetic devices. APPROACH: Two RPNIs were created in each of two rats by grafting portions of free muscle to the ends of divided peripheral nerves (peroneal in the left and tibial in the right hind limb) and placing bipolar electrodes on the graft surface. After four months, we examined in vivo electromyographic signal activity and compared these signals to muscular electromyographic signals recorded from autologous muscles in two rats serving as controls. An additional group of two rats in which the autologous muscles were denervated served to quantify cross-talk in the electrode recordings. Recordings were made while rats walked on a treadmill and a motion capture system tracked the hind limbs. Amplitude and periodicity of signals relative to gait were quantified, correlation between electromyographic and motion recording were assessed, and a decoder was trained to predict joint motion. MAIN RESULTS: Raw RPNI signals were active during walking, with amplitudes of 1 mVPP, and quiet during standing, with amplitudes less than 0.1 mVPP. RPNI signals were periodic and entrained with gait. A decoder predicted bilateral ankle motion with greater than 80% reliability. Control group signal activity agreed with literature. Denervated group signals remained quiescent throughout all evaluations. SIGNIFICANCE: In vivo myoelectric RPNI activity encodes neural activation patterns associated with gait. Signal contamination from muscles adjacent to the RPNI is minimal, as demonstrated by the low amplitude signals obtained from the Denervated group. The periodicity and entrainment to gait of RPNI recordings suggests the transduced signals were generated via central nervous system control.


Assuntos
Eletromiografia/métodos , Marcha/fisiologia , Músculo Esquelético/fisiologia , Músculo Esquelético/transplante , Regeneração Nervosa/fisiologia , Nervos Periféricos/fisiologia , Animais , Eletrodos Implantados , Membro Posterior/inervação , Membro Posterior/fisiologia , Masculino , Músculo Esquelético/inervação , Ratos , Ratos Endogâmicos F344 , Transplantes/inervação , Transplantes/fisiologia , Caminhada/fisiologia
19.
IEEE Trans Haptics ; 9(3): 387-96, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27101616

RESUMO

An important goal of haptic display is to make available the action/reaction relationships that define interactions between the body and the physical world. While in physical world interactions reaction cues invariably impinge on the same part of the body involved in action (reaction and action are colocated), a haptic interface is quite capable of rendering feedback to a separate body part than that used for producing exploratory actions (non-colocated action and reaction). This most commonly occurs with the use of vibrotactile display, in which a cutaneous cue has been substituted for a kinesthetic cue (a kind of sensory substitution). In this paper, we investigate whether non-colocated force and displacement cues degrade the perception of compliance. Using a custom non-colocated kinesthetic display in which one hand controls displacement and the other senses force, we ask participants to discriminate between two virtual springs with matched terminal force and adjustable non-linearity. An additional condition includes one hand controlling displacement while the other senses force encoded in a vibrotactile cue. Results show that when the terminal force cue is unavailable, and even when sensory substitution is not involved, non-colocated kinesthetic displays degrade compliance discrimination relative to colocated kinesthetic displays. Compliance discrimination is also degraded with vibrotactile display of force. These findings suggest that non-colocated kinesthetic displays and, likewise, cutaneous sensory substitution displays should be avoided when discrimination of compliance is necessary for task success.


Assuntos
Cinestesia/fisiologia , Fenômenos Mecânicos , Percepção/fisiologia , Adulto , Sinais (Psicologia) , Retroalimentação , Feminino , Mãos , Humanos , Masculino
20.
IEEE Trans Haptics ; 8(3): 287-97, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25879973

RESUMO

The increased access to books afforded to blind people via e-publishing has given them long-sought independence for both recreational and educational reading. In most cases, blind readers access materials using speech output. For some content such as highly technical texts, music, and graphics, speech is not an appropriate access modality as it does not promote deep understanding. Therefore blind braille readers often prefer electronic braille displays. But, these are prohibitively expensive. The search is on, therefore, for a low-cost refreshable display that would go beyond current technologies and deliver graphical content as well as text. And many solutions have been proposed, some of which reduce costs by restricting the number of characters that can be displayed, even down to a single braille cell. In this paper, we demonstrate that restricting tactile cues during braille reading leads to poorer performance in a letter recognition task. In particular, we show that lack of sliding contact between the fingertip and the braille reading surface results in more errors and that the number of errors increases as a function of presentation speed. These findings suggest that single cell displays which do not incorporate sliding contact are likely to be less effective for braille reading.


Assuntos
Cegueira/reabilitação , Apresentação de Dados , Leitura , Tecnologia Assistiva , Auxiliares Sensoriais , Tato , Adulto , Simulação por Computador , Sinais (Psicologia) , Feminino , Dedos , Humanos , Masculino , Pessoa de Meia-Idade , Percepção de Movimento/fisiologia , Propriocepção/fisiologia , Tempo de Reação/fisiologia , Interface Usuário-Computador , Adulto Jovem
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